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Zithromax IV

Generic Name: Azithromycin (oral or injection) [a-ZITH-roe-MYE-sin]
Names of Brands: Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax IV, Zithromax TRI-PAK, Zithromax Z-Pak
Drug class: macrolides

What is Zithromax IV?

Zithromax IV is used to treat bacterial infections such as lung infections and throat, sinuses, tonsils, skin, urinary tract, cervix, and genitals.Zithromax IV can also be used to treat conditions not covered in this medication guide.

Side effects of Zithromax IV

Seek medical attention immediately. If you notice symptoms that indicate an allergic reaction (hives and breathing problems or swelling of your throat or face) or an extreme skin reaction (fever and irritation of your throat and eyes, burning sensations in your eyes, skin irritation, and red or purple skin itching that can cause peeling and blisters),

Get medical attention when you experience a severe drug reaction that affects the body in a variety of ways. Symptoms may include the following: a skin rash or fever; swelling of the glands; muscle aches; abnormal bruising; severe weakness; or redness of your eyes or skin.

Zithromax IV may cause serious adverse effects. Consult your physician immediately in the event that you suffer from:

  • Extreme stomach pains; diarrhea that is bloody or watery;
  • Rapid or pounding heartbeats, chest fluttering, shortness of breath, and a sudden feeling of dizziness (like you're about to pass out)
  • Liver issues—nausea, vomiting, and loss of appetite. Stomach discomfort (upper right): fatigue, itching, black stools, dark urine, jaundice (yellowing of the eyes or skin);

Contact your doctor immediately when a baby who is taking Zithromax IV becomes irritable or vomits during feeding or eating.

Seniors are more likely to experience negative effects on their heart rhythm, which could include a life-threatening high pace.

Common adverse reactions associated with Zithromax IV may include:

  • Nausea, vomiting,
  • Stomach pain.

This isn't a complete list of all the side effects. Other effects may also be present. Contact your doctor to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


It is not recommended to use Zithromax IV if you have previously experienced any allergic reactions, jaundice, or liver problems when taking Zithromax IV. It is not recommended to use this medication if you have ever experienced an extreme allergic reaction to similar medications like clarithromycin, erythromycin, or telithromycin.

Before you take this drug

You shouldn't take Zithromax IV if you are allergic to it or have ever experienced:

  • The liver or jaundice that results from the use of Zithromax IV;
  • An extremely allergic response to medications such as erythromycin, clarithromycin, or telithromycin.

Zithromax IV oral shouldn't be used for treating pneumonia for those who suffer from:

  • Cystic fibrosis;
  • Following a stay in a hospital
  • An infection in the bloodstream;
  • A weak immune system (caused by illnesses like HIV/AIDS as well as cancer)
  • For older adults and those who are sick or have a debilitating condition.

Contact your doctor if had any of the following:

  • Pneumonia;
  • Kidney or liver disease
  • Myasthenia gravis;
  • Low levels of potassium present in your blood.
  • A heart rhythm disorder
  • Long QT syndrome (in either you or someone in your family).

It is not clear whether this remedy is effective for treating genital ulcers in women.

Talk to your physician if are nursing or expecting. The use of Zithromax IV while breastfeeding may cause vomiting, diarrhea, or a rash on the baby who is nursing.Zithromax IV is not approved to be used by anyone younger than six months old. Zithromax IV is not recommended to treat a tonsil or throat infection in children younger than 2 years of age.

How to take Zithromax IV?

Follow the directions on the prescription label and also read all medication guides or instruction sheets. Make sure you use the medication precisely as directed.

Zithromax IV orally is a medicine taken by mouth. The medicine is administered by infusion into the vein, typically for 2 days prior to switching to oral. Your healthcare provider will offer the injection.You can consume Zithromax IV orally with or without food.Shake up the oral suspension (liquid) prior to taking the dosage. Make use of the dosing syringe supplied or use a dosage-measuring device (not an ordinary spoon).

Make sure to use Zithromax IV for the full prescribed duration of time, regardless of whether your symptoms improve quickly. Inadequate doses could increase your chance of contracting an infection that is resistant to treatment. Zithromax IV will not treat a viral disease like influenza or the typical cold.

Keep at room temperature, away from heat and moisture. Get rid of any leftover medicine in liquid medicine after a period of 10 days.

What happens if I miss the dose?

Do not take the medicine for as long as you are able, but do not take your missed dose if it's close to the time of the next dose. Don't take two doses at a time.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

Avoid this

Antibiotic medications can trigger diarrhea, which can be an indication of a new infection. If you experience diarrhea that is bloody or watery and you are unable to get a doctor's appointment, consult your doctor prior to taking anti-diarrhea medication.

Zithromax IV can cause you to burn more quickly. Avoid tanning beds and sunlight. Be sure to wear protective attire and sunblock (SPF 30 or more) while you're outdoors.

Interaction with other drugs

Inform your doctor about any other medications you take, including:

This list isn't exhaustive. Other medications can influence Zithromax IV, including prescription and over-the-counter medicines, vitamins, and herbal supplements. There are many possible interactions between drugs that are included here.



Prescription only

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