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Zicam Extreme Congestion Relief

Generic Name: Oxymetazoline nasal [ox-ee-me-TAZ-oh-leen-NAY-sal]
The brand names are: 12 Hour Nasal Decongestant for 12 Hour Nasal, Afrin, Afrin All Night NoDrip, Afrin Allergy Sinus, etc. Display the 35 brand names.
The Class of Drugs: Nasal antihistamines and decongestants

What is Zicam Extreme Congestion Relief?

Oxymetazoline is a decongestant that reduces blood vessels in the passageways to and from the nose. Blood vessels that are dilated can cause nose congestion (stuffy nostrils).

Zicam Extreme Congestion Relief (for the nose) is a temporary relief from nose congestion (stuffy nose) that is caused by allergies or the common cold.Zicam Extreme Congestion Relief may be used for other purposes that are not mentioned in this guideline.

Side effects of Zicam Extreme Congestion Relief

See a doctor immediately. If you experience any of the following symptoms as warning signs of reactions to an allergen, such as hives, difficulty breathing, or swelling of your lips, face, or tongue,

Zicam Extreme Congestion Relief may cause severe adverse effects. Stop taking Zicam Extreme Congestion Relief and consult your physician immediately in the event that you experience:

  • Chronic or worsening symptoms;
  • Intense burning or stinging sensations in your nose after applying the spray to your nose;
  • Chest pain, rapid or irregular heart rate,
  • A severe headache that causes a buzz inside your ears, anxiety, disorientation, or feeling exhausted.

Common adverse consequences of zicam extreme congestion relief may include:

  • Minor burning or stinging sensations in the nose;
  • Sneezing;
  • Nose that is runny.

This isn't a complete list of possible side effects, and other effects may also be present. Contact your doctor for advice regarding medical effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Similar/related drugs

epinephrine topical, pseudoephedrine, phenylephrine nasal, sodium chloride nasal, and Afrin


Zicam Extreme Congestion Relief (for the nose) is used to provide temporary relief from nasal congestion due to allergies or the common cold.

Take a break from using Zicam Extreme Congestion Relief and consult your physician immediately if you are experiencing persistent or worsening symptoms or if you experience intense burning or stinging sensations in your nose following the use of the spray for your nose.

Before you take this drug

You shouldn't use Zicam Extreme Congestion Relief if you have an allergy to it.

Consult a pharmacist or doctor to determine if it's appropriate for you to take this medication in the event of any other medical conditions, including:

  • Coronary illness, high blood pressure, coronary artery disease;
  • Diabetes;
  • An thyroid disorder;
  • An enlarged prostate or urinary problems.

FDA classification for pregnancy C It isn't known how Zicam Extreme Congestion Relief will affect a newborn baby. Consult your physician if you are expecting or plan to become pregnant while taking this medication.

It isn't known if the nasal oxymetazoline enters breast milk or whether it can harm the baby who is nursing. Consult your physician if you are breastfeeding a child.

How to take Zicam Extreme Congestion Relief?

Follow the directions on the label or as directed by your physician. Don't use in greater than smaller amounts or for a longer period than is recommended.

Injecting the medicine excessively or frequently could aggravate conditions or trigger nasal congestion that will disappear and then return.

Consult your doctor if symptoms don't improve after three weeks of therapy.

Do not give this medication to someone else, even if they suffer from the same symptoms as you do. Sharing the nasal spray bottle could be a way to spread an infection.

To use the drops for the nose (nasal solution):

  • Blow your nose gently Turn your head to the maximum extent you can, or lay down and hang your head on the side of your mattress. Place the dropper in your nose, and then place the appropriate amount of drops inside your nose.
  • Then, sit up and flex your head slightly forward, then slowly move it left and to the right. Sit with your head slightly bent for a couple of minutes.
  • Do not blow or sneeze your nose for several minutes following the application of the drops.

For use with the spray for nasal use:

  • Breathe through your nose slowly. Maintain your head in a straight position, and then insert the bottle's tip into one nostril. Close the other nostril by using your finger. Breathe deeply and gently spray the medication through your nose. You can then spray the other nostril.
  • Don't use your nose to blow for several minutes following the application of the spray to your nose.

Don't use the spray on your nose more than twice in 24 hours.

Cleanse the top of the spray bottle using unclean tissue. Do not rinse it with soap or water.

Keep at room temperature, free of heat and moisture. Don't freeze. Close the bottle when not being used.

What happens if I miss the dose?

Utilize the dose you missed immediately after you recall. Avoid any missed doses if it's nearing the time for the next dose. Don't use any extra medication to make up for the missed dose.

What happens if I overdose?

Get medical attention immediately or contact the Poison Help line at 1-800-222-1222 in the event that anyone has accidentally swallowed the medicine.

Make sure to keep Zicam Extreme Congestion Relief out of the reach of kids. Certain nasal medications could cause serious medical issues in children who swallow or suck in medication out of the bottle that contains nasal spray.

Avoid this

Follow your doctor's advice regarding any restrictions regarding drinks, food, or any activity.

Interaction with other drugs

Consult a physician or pharmacist to determine whether it is safe to take Zicam Extreme Congestion Relief if you're also taking one of the following medications:

  • An antidepressant—amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline;
  • Ergot medicine—ergotamine, dihydroergotamine, ergonovine, methylergonovine;
  • An mao inhibitor—isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

This list isn't complete, and other drugs could be incompatible when used in conjunction with Zicam Extreme Congestion Relief. Discuss with your doctor the medications you are taking. This includes prescriptions, over-the-counter vitamins, and herbal remedies. Don't start any new medication without first talking to your physician.