The Web Health



Generic Name: Vilazodone (vilaz-ohdone)
Brand names: Viibryd Starter
Drug class: antidepressants

What is Viibryd?

Viibryd belongs to a class of antidepressants called Select Serotonin Reuptake Inhibitors.Viibryd treats major depressive disorder (MDD).Viibryd may be safe and effective in treating MDD in children, but it is not yet known.


Viibryd should not be used if an MAO inhibitor has been taken in the last 14 days. Examples include isocarboxazid (linezolid), phenelzine (phenelzine), tranylcypromine, and others. It is possible that a dangerous drug interaction will occur.

When first starting an antidepressant, some young people (children or adults under 24 years of age) may have suicidal thoughts. Be alert to any changes in mood or symptoms. Notify your doctor of any new symptoms or symptoms that worsen.Viibryd should not be used by anyone under the age of 18.Consult your doctor before stopping Viibryd.

Before you take this drug

Viibryd should not be used if MAO inhibitors have been taken in the last 14 days. It is possible that a dangerous drug interaction will occur. MAO inhibitors are isocarboxazid and linezolid.You must wait 14 days after stopping Viibryd before taking maois.

Inform your doctor if any of these medications are also being taken: stimulant medicines, opioids, herbal products, medicine for mental illness, Parkinson’s disease, migraine headaches, or serious infections. Viibryd can cause serotonin-induced syndrome, a serious condition.

Tell your doctor about any of the following to ensure that Viibryd will be safe for you:

  • Liver or kidney disease
  • A bleeding or blood clotting disorder;
  • Narrow-angle glaucoma;
  • Seizures or epilepsy;
  • Bipolar disorder (manic depression);
  • Sexual problems
  • Drug addiction or thoughts of suicide
  • If you are a heavy drinker of alcohol,

As they adjust to an antidepressant medication, some young people may have suicidal thoughts when first beginning antidepressants. Regular visits to your doctor are a good way for you and your doctor to monitor the progress of your treatment. You or your family members should be aware of any changes in mood or symptoms.It is not safe to stop taking this medication during pregnancy. Consult your doctor before starting or stopping Viibryd.

You may find your name on a registry for pregnant women to monitor the effects of the drug on the child.Ask your doctor if you can safely breastfeed while taking this medication.No one under 18 years of age may use this product.

Similar/related drugs

Sertraline, Trazadone, Lexapro, Zoloft, Citalopram, Cymbalta, and Wellbutrin

How to take Viibryd?

Follow all instructions listed on your prescription label and review all medication guides or instruction sheets. Read all the instructions and directions that come with your prescription. Sometimes your doctor will change the dose.Viibryd can be taken with food.You may experience symptoms that persist for several weeks.Inform your doctor about any changes you experience in sexual function. Certain sexual problems are treatable.

Viibryd should not be stopped suddenly. You may experience unpleasant symptoms, such as agitation or confusion. Before stopping the medication, consult your doctor.Store away from heat and moisture at room temperature.

Details on dosage

Adult dose for depression:

Initial dose: orally, 10 mg once daily for 7 days. Then 20 mg once daily for another 7 days.
Maintenance dose: 40 mg orally, once daily.
Take this drug with food.
Use: Treatment for major depression disorder (MDD).

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.

What happens if I overdose?

Call Poison Help at 1-800-222-1222 or seek emergency medical care. A vilazodone overdose can be fatal.

What should be avoided?

Alcohol consumption can have side effects when taken with this medication.Ask your doctor if you should take a nonsteroidal inflammatory drug (NSAID), such as Advil, ibuprofen, or naproxen. Viibryd and nsaids can cause you to bleed or bruise easily.Do not drive or engage in hazardous activities until you have determined how the medicine will affect you. You may be unable to react properly.

Side effects of Viibryd

If you experience any of the following: skin reactions, hives, difficulty breathing, swelling of your lips, face, tongue, or throat,

You should tell your doctor if any symptoms worsen or change, including changes in mood or behavior, anxiety, panic attacks, or trouble sleeping. Also, you may feel more impulsive, agitated, hostile, or aggressive.

If you experience:

  • A seizure (convulsions);
  • Blurred vision, tunnel vision, eye swelling or pain, or seeing halos around lights
  • Easy bruising and unusual bleeding
  • If you experience racing thoughts, increased risk-taking, reduced inhibitions, extreme feelings of happiness or sadness, or decreased inhibitions,
  • Low sodium levels in the body—headache

Serotonin syndrome symptoms include: hallucinations and agitation; fever, sweating, or shivering; rapid heartbeat; muscle stiffness or twitching; and loss of coordination.

Viibryd may cause side effects such as:

  • Nausea, vomiting;
  • Diarrhea;
  • Sleep problems (insomnia).

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Viibryd can make you more drowsy if taken with other drugs. Before taking an opioid, sleeping pill, muscle relaxant, anxiety medicine, or medication for seizures, consult your doctor.

Inform your doctor of all medications you are currently taking. Many drugs, including:

  • Any other antidepressants?
  • Mephenytoin;
  • John's Wort;
  • Tramadol;
  • A diuretic, or "water pill".
  • Medicine to treat mental illnesses such as schizophrenia or anxiety disorders;
  • A blood thinner Warfarin Coumadin Jantoven
  • Sumatriptan (Imitrex), Maxalt, Treximet, and other migraine headache medicines

The list of drugs that may interact with vilazodone is not exhaustive. These include prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all drug interactions.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories