The Web Health


Vaseretic 10-25

Generic name: hydrochlorothiazide and enalapril [HYE-droe-KLOR-oh-THE-azide-and-en-AL-april]

Drug class: ACE inhibitors with thiazides

What is Vaseretic 10–25?

Hydrochlorothiazide is a diuretic thiazide (water pill), and Enalapril acts as an ACE inhibitor (ACE is the abbreviation for angiotensin-converting enzyme).

Vaseretic 10-25, also known as 10-25 mixture medicine, is used to treat hypertension (high blood pressure).Vaseretic 10–25 could also be used to treat conditions that are not mentioned in this guide.

Side effects of Vaseretic 10–25

Seek medical attention immediately when you are experiencing symptoms that indicate an allergy (hives or stomach pains that are severe, breathing difficulties, and swelling of your throat or face) or an intense skin reaction (fever or burn sensations in your eyes, pain in the skin, and the skin is red or purple, which spreads and leads to blisters as well as peeling).

You are more likely to experience allergies if you are African-American.

Vaseretic 10–25 can result in serious unwanted side effects. Contact your physician immediately. If you suffer from:

  • Euphoric feeling, similar to when you're about to pass out.
  • Jaundice (yellowing of the eyes or skin);
  • Blurred vision blurred vision, tunnel vision, eye pain, or seeing halos around light sources;
  • Chills, fever chills,-like symptoms of colds, tongue sores, sore throat
  • Symptoms of an electrolyte imbalance: leg cramps, constipation, muscle discomfort, or an irregular heartbeat experiencing jitteriness; an increase in thirst or urination; numbness; a feeling of tingling; a loss of motion;
  • Kidney issues: little or no urinary frequency, swelling in your ankles or feet, and feeling exhausted or sluggish
  • New or worsening symptoms of the lupus and lupus-related symptoms. Joint pain and a skin eruption on your cheeks or arms that gets worse in the sun.

Common adverse results of Vaseretic 10–25 could include:

  • Dizziness;
  • Cough;
  • Headache
  • Nausea.

This is not a comprehensive list of possible side effects, and other side effects could be present. Contact your doctor for advice regarding medical adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Amlodipine, lisinopril, metoprolol, losartan, furosemide, carvedilol, and hydrochlorothiazide


Avoid using it when you are expecting. If you find yourself pregnant, take Vaseretic 10–25 off and notify your doctor as soon as you notice.

It is not recommended to use this medication if you're unable to urinate, have ever suffered from angioedema, or are sensitive to Sulfa medications and/or some ACE inhibitors. Do not use Vaseretic 10–25 in the first 36 hours of using a medicine containing sacubitril (such as Entresto).

If you suffer from diabetes, don't take Vaseretic 10–25 with any medication containing Aliskiren (a blood pressure medication).

Before you take this drug

It is not recommended to use this medicine if you're allergic to hydrochlorothiazide and enalapril or if you suffer from:

  • You are not able to go to the bathroom.
  • If you've ever experienced angioedema,
  • You recently took an anti-heart medicine known as sacubitril.
  • You are averse to sulfa-based drugs. You are allergic to sulfa-based drugs.
  • You are sensitive or allergic to any ACE inhibitor (benazepril, captopril, moexipril, lisinopril, quinapril, and the drug trandolapril).

Take care not to take Vaseretic 10–25 within the first 36 hours prior to or following the taking of medication that contains sacubitril (such as Entresto).If you suffer from diabetes, take care not to make use of Vaseretic 10-25 with other medicines that contain Aliskiren (a blood pressure medication).

It is also possible to stay clear of taking Vaseretic 10–25 along with aliskiren when you suffer from kidney problems.

Inform your doctor if you have ever suffered from:

  • Asthma or allergies
  • Renal disease (or if you're taking dialysis);
  • Cirrhosis or another liver disease;
  • Glaucoma;
  • Congestive heart failure;
  • Gout;
  • The imbalance of electrolytes (such as a low level of magnesium, potassium, or magnesium in the blood);
  • Lupus;
  • If you're allergic to penicillin
  • If you are following a diet low in salt,

Do not take this medicine in the event that you are expecting. If you are pregnant, stop taking this medication and inform your doctor now. Enalapril can cause injury or even death to an unborn baby if you use the medication in the second or third trimester.You shouldn't breastfeed when taking this medication.

How to take Vaseretic 10-25?

Follow the directions on the prescription label and go through all medication guides or instructions. The doctor might alter your dosage. Make sure you take the medicine exactly as prescribed.Contact your physician if you are experiencing persistent diarrhea or have been sweating more than normal. It is easy to get dehydrated when taking Vaseretic for 10–25 days. This could lead to high blood pressure, electrolyte issues, or kidney failure.

Your blood pressure is likely to be monitored regularly. The kidneys function could also require a check. Your urine and blood could be examined when you've had a vomiting episode or are dehydrated.If you are in need of surgery, inform the surgeon in advance that you're using Vaseretic 10–25.

Use Vaseretic 10–25 only according to the directions, regardless of whether you feel good. A high blood pressure can have no signs. You could need blood pressure medications throughout your life.Keep the tablets at room temperature, free of heat, moisture, and light. Place the tablets in their original containers together with the package or canister of preservative that absorbs moisture.

What happens if I miss the dose?

Do not take the medicine for as long as you can. However, do not take any missed doses if it's nearing the time to take the next dose. Don't take two doses at a time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.Some symptoms of overdose include an increase in thirst, feeling lightheaded, and falling asleep.

What should be avoided?

Avoid using the potassium supplement or salt replacement except if your doctor has advised you to.

Beware of becoming dehydrated or overheated during workouts, in hot weather, or by drinking insufficient fluids. Follow your doctor's advice on the amount and type of fluids you need to drink.

Be careful not to get up too quickly from a lying or sitting position. You could be dizzy.Drinking alcohol can cause an increase in certain negative effects that come with Vaseretic 10–25.

Interaction with other drug

Discuss with your doctor the medicines you are currently taking. A variety of drugs may affect Vaseretic 10–25, particularly:

  • Other blood pressure medications and other diuretics, such as another diuretic (also known as a "water pill");
  • Digoxin;
  • Lithium;
  • Cancer medicine;
  • Gold injections for the treatment of the symptoms of arthritis;
  • Insulin, or oral diabetes medicine;
  • A muscle relaxer;
  • Medicine to prevent organ transplant rejection—cyclosporine, everolimus, sirolimus, tacrolimus,
  • The nsaids (nonsteroidal anti-inflammatory drugs) are aspirin, Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac (also known as indomethacin), diclofe, and many others.

The list below is not exhaustive, and a variety of other medications could impact Vaseretic 10–25. This includes prescription and over-the-counter medications, vitamins, and herbal supplements. There are many possible interactions between drugs that are included here.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories