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Synera

Generic name: lidocaine and tetracaine topical [LYE-doe-kane-and-TET-ra-kane-TOP-i-kal]

Brand name: Synera
Drug class: Topical Anesthetics

What is Synera?

Synera patches are a mixture of lidocaine and tetracaine. Local anesthetics are tetracaine and lidocaine. These medicines work by blocking the nerve signals within your body.

Synera patches can be used to numb small areas of skin. This can be used to prevent pain when undergoing certain medical procedures, such as a minor skin surgery or a biopsy. The patches can also be used to numb an area of skin when performing minor cosmetic procedures, such as Botox, laser treatments, or tattoo removal.

Warnings

If you use more than the recommended dosage or leave the Synera patch on for too long, you may experience fatal side effects. Synera skin patches, both used and unopened, should be kept out of reach of children and pets.

Before you take this drug

Synera should not be used if you have an allergy to:

  • Any type of numbing medication;
  • Paraaminobenzoic (PABA) acid can be found in sunscreen and other skin care products containing paraaminobenzoic (PABA).

Overdoses of numbing medicine have been fatal when used without the doctor's advice (for example, during cosmetic procedures like laser hair removal). Many cosmetic procedures are done without the presence of a doctor.

Skin patches for Synera are not recommended for anyone under the age of 18. Tell your doctor about any of the following to ensure that Synera will be safe for you:

  • Liver disease
  • Methemoglobinemia may affect you or a member of your family;
  • A genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
  • A condition for which you are taking medicine to regulate your heartbeat;
  • Allergy to any anesthesia drug.

This medicine may have a greater effect on older adults or people with disabilities. Inform your doctor if you are pregnant or nursing. Avoid areas where the mouth of a baby may be in contact with lidocaine or tetracaine.

If you wear the Synera Transdermal Patch during an MRI, it may cause your skin to burn. Before undergoing any such test, remove the patch.

Similar/related drugs

Lidocaine ophthalmic, cocaine nasal, and buprevacaine

How to take Synera?

Follow the instructions on your prescription label and read all medication guides or instruction sheets. Read all the instructions and directions included on the prescription label. Use this medication only as prescribed. Do not exceed the prescribed dosage and do not use it for more than its recommended period. The medicine should be applied between 20 and 30 minutes prior to your procedure or 60 minutes prior to tattoo removal.

You should carefully read any instructions for use that come with your medication if you are using Synera at home.If you don't understand the instructions, consult your doctor or pharmacist. Take it only by mouth. Topical medicines are only to be used on the skin. Rinse with water if this medicine enters your mouth, nose, or rectum. A healthcare professional will apply the medicine to your skin for a cosmetic procedure.

Synera patches should only be applied to healthy, clean skin that is dry and free of any blemishes. Avoid raw or blistered skin. Press the patch into place firmly. It is normal to feel warm, but not unbearably hot. After applying the Synera patch, wash your hands. Remove the skin patch after the prescribed time. Then, clean and disinfect your skin according to your doctor's instructions.

Fold the skin patch in half, sticky side facing out. Throw it away somewhere that is not accessible to children or pets. Store skin patches away from moisture, heat, and moisture at room temperature. Synera skin patches, both used and unused, should be kept away from children or pets. If a child or animal accidentally swallows or sucks the patch, it could cause harm.

Details on dosage

Adult dose for local anesthesia:

Apply one film to intact skin between 20 and 30 minutes prior to the procedure.

The usual pediatric dose for local anesthesia is:

Apply one film to the intact skin between 20 and 30 minutes prior to the procedure.

What happens if I miss the dose?

Synera does not require a daily schedule of dosage because it is only used in a single dose.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical attention. Too much painkiller medication may have fatal repercussions.

You may be absorbing too much medicine if you:

  • You should not exceed the recommended dosage.
  • You should not apply the medication to skin that has been cut or irritated.
  • You leave a Synera patch on your body for too long.

The symptoms of an overdose may include nausea, drowsiness, and slurred or numb speech. Overdoses of lidocaine and tetracaine can cause serious complications, including seizures, slowed respiration, coma, or heart failure (breathing stops).

What should be avoided?

Avoid letting this medication come into contact with your eye. If this happens, rinse your eyes with water. If the patch has been damaged or cut, do not use it. When applying a skin patch, avoid touching the sticky side.

Avoid receiving a "live vaccine" while using lidocaine or tetracaine. It may not protect you as well from disease, and the vaccine may not perform as well. Live vaccines are measles (MMR), rubella, typhoid (rotavirus), yellow fever (typhoid), varicella, chickenpox, zoster, shingles, polio (typhoid), rotavirus (typhoid), syphilis (typhoid), sy

Side effects of Synera

If you experience any of the following symptoms of an allergic reaction: hives, wheezing, or difficulty breathing; swelling of your lips, face, tongue, throat, or face;

If you experience:

  • The medicine may cause severe irritation, such as burning, stinging, or other symptoms.
  • After taking the medicine, you may experience sudden drowsiness and dizziness.
  • Skin that is pale, gray, or blue in color;
  • Headache; rapid heartbeats; shortness of breath
  • Tiredness or the feeling that you could pass out
  • You may experience blurred vision or ringing in the ears.
  • Unusual sensations of heat or cold

Synera is associated with the following side effects:

  • Skin redness;
  • Skin swelling
  • Changes in the skin color at the site of application.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Other drugs that you take are unlikely to affect the medicine used on your skin. Some drugs may cause side effects that make Synera dangerous. Inform your healthcare provider about any medicines you are taking, including over-the-counter and prescription medicines, vitamins, and herbal products.