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Name of the generic: solriamfetol Solriamfetol SOL-riAM-fe’tol [ SOL-ri-AM-fetol
Drug class: Miscellaneous central nervous system agents

What is Sunosi?

Sunosi is a prescribed medicine that is used to treat excessive sleepiness during the daytime in adults suffering from narcolepsy or those whose sleep is disturbed due to sleep apnea. Sunosi cannot treat sleep apnea. Continue using the CPAP machine or other equipment prescribed by your doctor. It is not clear whether Sunosi is safe or effective for children.


Don't use Sunosi if you've used an MAO inhibitor within the past 14 days, like linezolid, isocarboxazid, Methylene Blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.Sunosi is a federally regulated substance because it contains solriamfetol. This medication could be an ideal target for those who misuse prescription drugs as well as street drugs.

Make sure to keep your Sunosi in a safe location to guard it against theft. Don't offer your sunosi to someone else, as it could cause the death of someone else or cause harm to the person. Giving away or selling this medication could cause harm to others and is against the law. Talk to your doctor if you've ever taken or become dependent on prescription drugs, alcohol, or street drugs.

Before you start taking this medicine

If you suffer from sleep apnea or other sleep disorders, you must be treated for at least one month prior to starting Sunosi.Do not take Sunosi if you've taken an MAO inhibitor within the last fourteen weeks. A dangerous drug interaction can happen. MAO inhibitors are isocarboxazid, the linezolid drug, Methylene Blue injection, rasagiline, phenelzine, tranylcypromine, and others.

To make sure that this medication is appropriate for you, tell your doctor if you have any of the following:

  • Heart-related problems;
  • A heart attack or stroke
  • High blood pressure;
  • Diabetes;
  • High cholesterol;
  • Kidney disease;
  • Mental illness, psychosis, bipolar disorder, or
  • Alcoholism or addiction to drugs (especially dependence on cocaine or other stimulants)

If you're expecting, then your name might be included on an OB-GYN registry to monitor any effects that solriamfetol has on the infant. Inform your doctor if you are nursing. Contact your doctor if you observe disturbances or sleep issues, as well as a decreased appetite. less weight gain for the nursing infant.Sunosi is not a product that has been approved for use by anyone less than 18 years old.

How to take Sunosi?

Use Sunosi exactly as directed by your physician. Follow all instructions on the label of your prescription, and make sure you read all the prescription guides or instructions sheets. Your doctor may modify your dosage. Sunosi is generally taken every day at the time you get up. You can use Sunosi in combination with food or not. You might need to swallow the tablet completely or break it into two pieces. Follow the instructions of your physician cautiously.

Be sure to follow the instructions of your doctor on when you should raise your dosage. Doing more solriamfetol in excess of what is recommended does not improve its effectiveness and could cause serious adverse side effects. Your heart rate and blood pressure should be monitored regularly. Solriamfetol could be addictive. Intoxication can result in addiction, overdose, or even death. Keep the medication in a location where other people can't access it. Giving away or selling the medicine is against the law. Do not alter your dosage or cease taking Sunosi without consulting your physician.

Keep at room temperature, free of heat and moisture. Be aware of the medication you are taking. It is important to be aware if you are using the medicine improperly or without a prescription. Don't keep any Sunosi leftovers. Ask your pharmacist to find a take-back program for disposal. If there isn't a take-back program, you must follow the disposal instructions provided in the medication guide included with your medication.

Details on dosage

Usual Adult Dose for Narcolepsy:

Initial dosage: 75 mg orally once daily at the time of waking.
The dose could be increased after 3 days based on effectiveness and tolerability.
Dosage for maintenance: 75 to 150 mg taken orally every day.
Maximum dose: 150 mg/day

A dosage of 150 mg or more per day has not been proven to boost efficiency enough to offset the adverse effects associated with doses.

Use: To increase the quality of wakefulness for patients who suffer from excessive sleepiness in the morning due to narcolepsy.

Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:

The first dose is 37.5 mg once every day at the time of awakening.
The dose can be increased at intervals of 3 days based upon its effectiveness and the degree of tolerance.
Dosage for maintenance: 37.5 to 150 mg daily, orally
Maximum dose: 150 mg/day

This drug is not able to treat the airway obstruction that is the cause of sleep apnea with obstructive snoring (OSA).
Prior to starting treatment, patients must be able to have their obstruction to the airways treated (e.g., by continuous negative airway pressure) for at least 1 month. Patients should also keep treatment going when taking this medication.
Doses of more than 150 mg/day have not been proven to boost effectiveness to the point that they outweigh adverse reactions related to dose.

Use: To increase the amount and quality of sleep in patients suffering from excessive sleepiness during the day that is associated with OSA.

What happens if I miss a dose?

Do the medication as quickly as you can, but only if you are planning to remain awake for a minimum of 9 hours. Don't take two doses at once.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

Avoid this

Be sure to avoid taking this medicine within nine hours before the time you are planning to fall asleep; otherwise, you could have difficulty sleeping.

Side effects of Sunosi

Get immediate medical attention. If you are experiencing symptoms that indicate you are experiencing an allergic reaction, Sunosi: hives, breathing problems, or swelling of your lips, face, and tongue.

Contact your doctor immediately. If you suffer from:

  • Racing thoughts, more energy levels, less need for sleep, feeling anxious or angry;
  • Chronic sleep disorders;
  • Rapid heartbeats, fast beats, or
  • A severe headache,  blurred vision, or the pounding of your neck or ear.

Common Sunosi side effects can include:

  • Difficulty sleep;
  • Anxiety;
  • Nausea and nausea; or

This isn't a complete list of possible side effects, and others could happen. Contact your doctor to seek medical advice on adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Other medications may interfere with solriamfetol. This includes prescription and non-prescription medicines, vitamins, and herbal products. Inform your physician about all the medicines you are currently taking as well as any medications you are about to start or stop taking.




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