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Generical name: Buprenorphine (oral or sublingual) BUE-pre-NOR-feen 

Subutex is a brand name. Subutex’s brand name is removed within the U.S. If the generic versions of this product are cleared by the FDA, There may be similar generic versions available.

What is Subutex Sublingual?

Subutex can be described as an opioid. Sometimes, opioids are referred to as narcotics. Subutex sublingual tablets are prescribed to treat addiction to opioids. buprenorphine that can be utilized to treat severe to moderate pain. Subutex sublinguals should not be used as a painkiller.


Subutex tablet sublinguals should not be used as a painkiller.Opioid medicine taken during pregnancy could trigger withdrawal symptoms that could be life-threatening for the baby. The risk of fatal side effects could occur when you mix opioids in conjunction with alcohol or with other medications that cause drowsiness or a slowing of respiration.

Before you take this drug

Subutex should not be used if you are allergic to buprenorphine. Also,

  • If you've taken another opioid medication within the last four hours.

To be sure Subutex is safe for you, inform your physician if you've previously had:

  • Tooth problems, which may include a history of cavities
  • Methadone therapy, breathing difficulties, sleep apnea;
  • An abnormal curvature of the spine that affects breathing
  • The liver or kidney disease (especially liver disease, especially hepatitis B as well as C);
  • An increased prostate Prostate and urinary issues;
  • A head injury or brain tumor;
  • Alcoholism and hallucinations, or
  • Issues in your stomach, gallbladder, adrenal glands, and thyroid.

If you are using Subutex while pregnant, your baby may become dependent on the medication. This can cause severe withdrawal symptoms for the infant after it is born. Babies who become dependent on the drug can require medical attention for a few weeks.

Buprenorphine may be found in the breast milk of a nursing baby and cause drowsiness or breathing issues in nursing infants. Consult your physician regarding any potential risks.

Subutex is not permitted for use by anyone who is younger than

How to take Subutex?

Subutex sublinguals are usually used as a first step in treatment for addiction. Many people then switch to a different drug that contains the drug (Bunavail, Sublocade, Suboxone, or Zubsolv). It is possible to receive your first Subutex sublingual doses in a clinic or hospital, where you can wait until your condition improves. Do not share your opioid medication with anyone else, particularly those who have an addiction history. Misuse can cause addiction, overdosing, or death. Make sure the medication is stored in a location where other people aren't able to access it. The act of selling or giving away opioid medicines is illegal. Wash your mouth thoroughly with water once Subutex's sublingual tablet has disintegrated. After one hour, wait until the medicine has dissolved to brush your teeth in order to prevent damage to your gums and teeth. Avoid chewing the tablet or swallowing the whole tablet.In the event that your medical professional has given you more than two tablets for each dose, you should place the appropriate amount of tablets on your tongue at the same time and let them dissolve completely.

Don't eat, drink, or consume anything else until you are sure that the tablet has been completely dissolved inside your mouth. You should have regular dental exams while taking Subutex. You could require regular blood tests to determine the liver's function. If you require surgery, tell your surgeon in advance that you're taking Subutex. Do not break or crush the Subutex pills to inhale the powder or mix it with a liquid for injection through your vein. This could lead to the death of a person. addiction to opioids and are using Subutex as a sublingual. Make sure your family members are aware of what information to give in the event that they have to be able to help you in an emergency. Stop using Subutex abruptly; otherwise, you might experience uncomfortable withdrawal effects. Discuss with your doctor the best way to completely stop taking Subutex. Subutex is a medication that is abused, and you must be aware of any person who is taking the medicine in a way that is not approved or without having a prescription. Don't keep any of the leftover opioid medications. One dose could cause death if someone uses the medication in error or incorrectly. Ask your pharmacist where you can find a drug disposal program. If there's no take-back plan, dispose of the remaining medicine down the drain.

Details on dosage

Usual Adult Dose for Opiate Dependence: Maintenance:

Sublingual Tablets: After two days of induction:
Adjust dose in 2 to 4 mg increments or decrements to a level that holds the patient in treatment and suppresses opioid withdrawal signs and symptoms.
Dosage target: 16 mg every day; from 4–24 mg/day
The maximum dose is 24 mg per day. Higher doses haven't demonstrated a benefit in clinical trials.

Buprenorphine with naloxone is the preferred drug for maintenance treatment; unsupervised maintenance treatment with buprenorphine should be limited to those who cannot tolerate buprenorphine-naloxone.
When determining the quantity of prescriptions for administration without supervision, take into consideration the stability of the patient as well as the security of their home, as well as other factors that may influence the patient's ability to control supplies of home-based medication.

The monthly doses should allow at least a period of 26 days before the next dose. Sometimes, dosing delays of up to two weeks are unlikely to have a significant clinical impact on the treatment effect.

Usual Adult Dose for Opiate Dependence: Induction:

The treatment should begin when evident and obvious indications of moderate withdrawal from opioids are evident and
At least 4 hours have passed since the last use of heroin or other opioids with short-acting properties.
At a minimum, 24 hours have passed since the last time you used methadone or other opioids with long-acting properties.

Day one: eight mg taken sublingually every day (the dose may be administered in increments of 2 or 4 mg, if you prefer).
Day 2: 16 mg sublingually taken once per day.

This drug should be used in conjunction with a comprehensive treatment program that includes counseling and psychosocial assistance.
Buprenorphine (without naloxone) is the preferred drug for induction; following induction, unsupervised administration should be limited to those patients who cannot tolerate buprenorphine or naloxone.
A proper dose of treatment must be administered as quickly as possible, as a gradual increase over a period of time has resulted in more frequent dropout rates.

Uses: To treat opioid dependence, it is recommended for induction.

What happens If I miss a dose?

Do not take the medicine for as long as you are able, but do not take your missed dose if it's close to the time of the next dose. Don't take two doses at once.

What happens if I overdose?

Get medical attention immediately or contact the Poison Help line at 1-800-222-1222. An Subutex overdose could be fatal, particularly in children or anyone else using the drug without a prescription. Overdose symptoms can include severe weakness or drowsiness as well as a clammy or cold complexion, a pinpoint pupil, a low heart rate, and a weak pulse. extremely slow breathing, or the coma.

What should be avoided?

Avoid drinking or consuming alcohol. Dangerous side effects or death may occur. Do not drive or operate machinery until you understand how Subutex can affect you. Dizziness or drowsiness could cause accidents, falls, or serious injuries.

Side effects of Subutex sublingual

See a doctor immediately. If you exhibit symptoms of an allergy reaction, Subutex: hives, breathing difficulties, or swelling of your lips, face, and tongue.

Opioid medicines may slow or stop your breathing and cause death. The person who is caring for you should seek immediate medical care if you suffer from breath that is slow, with long pauses and blue lips, or if you find it difficult to get back up.

See your doctor right away if you are suffering from:

  • Any issues with your teeth or gums;
  • Sighing, noisy breathing, breath that is shallow, and breath that stops when you sleep
  • Issues with thinking blurred vision, slurred speech, and an uneasy feeling that you're about to pass out;
  • Chest pain, difficulty breathing, a slow heartbeat, or a weak pulse
  • Withdrawal symptoms of opioids include shivering, goosebumps, a lot of sweating, feeling cold or hot, runny eyes, a watery nose, muscle pain, diarrhea,
  • low levels of cortisol—dizziness, vomiting, and fatigue that gets worse or
  • liver issues nausea, abdominal pain, itching, and lack of appetite black stools, dark urine, and jaundice (yellowing of the eyes or skin).

Get medical attention immediately if you experience symptoms of serotonin disorder, like agitation, hallucinations, fever, sweating, shivering, rapid heart rate, muscle stiffness, shaking, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of Subutex include:

  • Constipation, nausea, vomiting;
  • Headache
  • More sweating;
  • Sleep problems (insomnia);
  • Any area of your body that is hurting.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

You might experience breathing issues or withdrawal symptoms if you discontinue or start taking other medications. Talk to your doctor if you are also using any antibiotic or antifungal medication. blood pressure or heart-related medicine, medication for seizures, or medicines for treating HIV as well as Hepatitis C.

Opioid medicine can interact with a variety of other medications and cause deadly side effects or even death. Be sure your doctor is aware if you are taking:

  • Medications for allergies or colds, bronchodilators for asthma or COPD, or diuretics ("water pills");
  • Medicines to treat motion sickness and irritable bowel syndrome medications for motion sickness, irritable bowel syndrome, or an overactive bladder;
  • Other opioid drugs, such as opioid pain medicine, as well as prescription-only cough medicines.
  • A sedative similar to Valium: diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and more;
  • Drugs that can make you feel sleepy or cause breathing to slow, such as a sleeping pill, a muscle relaxer, medication to treat mental or mood disorders,
  • Medications that alter serotonin levels within your body. stimulant or medication to treat Parkinson's disease, depression, migraine headaches, serious illnesses, nausea, and vomiting.

This list isn't complete. Other medications can interact with buprenorphine. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. The interactions with buprenorphine aren't all included here.