What is Sprix?
Sprix is an nsaid (nonsteroidal anti-inflammatory drug). Ketorolac reduces substances that are responsible for pain, fever, and inflammation.
Sprix nasal spray can be used by adults to treat moderate to severe pain for a short period of time (5 days or less). It has not been proven that sprix is safe and effective for patients aged 17 and under. Children under 2 years old should not use it.
Warnings
If you are suffering from severe kidney disease, have a bleeding disorder or a blood clotting disorder, or have a history of stomach bleeding or an ulcer, you should not take sprix. Do not use sprix nasal spray for more than 5 days.
Ketorolac may increase your risk of a fatal stroke or heart attack, even if there are no risk factors. This medicine should not be taken before or after a heart bypass (also known as a cabg).
Ketorolac can also cause fatal stomach or intestinal bleeding. You may be unaware of these potential health complications if you take this medication, particularly if you are an older individual. Pentoxifylline and probenecid may interact with ketorolac. They should not be taken together.
Before you take this drug
Even if you have no risk factors, sprix may increase your risk of a fatal heart attack or stroke. This medicine should not be used before or immediately after heart bypass surgery. Ketorolac can also cause fatal stomach or intestinal bleeding. You may not be aware of these conditions if you use this medication, particularly if you are older.
You should not use sprix if:
- Severe kidney disease
- A bleeding or blood clotting disorder;
- A closed brain injury;
- A stomach ulcer, a perforation, a history, or stomach or intestinal bleeding
- If you are breastfeeding a child,
- If you've ever experienced an asthma attack or a severe allergic reaction following the use of an nsaid or aspirin,
Ketorolac can be affected by pentoxifylline and probenecid. These drugs should never be taken together. Use sprix nasal spray only if you do not take aspirin, other nsaids, or any other form of ketorolac.
Tell your doctor if:
- Heart disease high blood pressure
- A heart attack, stroke, or blood clot
- Stomach ulcers or bleeding
- Crohn's disease or ulcerative colitis?
- Asthma;
- Liver or kidney disease
- Fluid retention;
- If you smoke.
Do not use sprix nasal spray if you are pregnant unless you have been told to by your doctor. Nsaids can cause kidney or heart problems in an unborn child and other complications during pregnancy. Sprix can temporarily reduce fertility.
Breast-feeding may not be possible while taking this medication. You should consult your doctor if you are concerned about any risks. Sprix nasal spray should not be used by children under 2 years of age.
How to take Sprix?
Follow the instructions on your prescription label and read all medication guides. Read all the instructions on the prescription label. Use the lowest effective dose to treat your condition. The spray is typically administered every 6–8 hours. Only use the prescribed number of sprays. Please carefully read and follow all instructions that accompany your medication. If you don't understand them, contact your physician or pharmacist immediately for clarification. If it is almost time for your next dose, skip any missed dosage. Never double up on any medication at the same time.
Use sprix no longer than five days, unless you have been told by your doctor to. This medicine comes in a bottle with 8 sprays that can be used within 24 hours. Even if the medicine is still inside, throw away the bottle 24 hours after first use. Store nasal sprays that have not been opened in the refrigerator. Do not freeze. Store the sprix nasal spray bottle at room temperature in a place that is dry and out of direct sunlight.
Details on dosage
Adult dose for pain:
nasal spray
weight 50 kg and more: 31.5mg every 6–8 hours (1 spray per nostril).
Weight less than 50 kg: 15,75 mg every 6–8 hours (1 spray per nostril).
Weight less than 50 kg: 63 mg
maximum dose; weight: 50 kg or more; 126 mg
The usual geriatric dose for pain:
-nasal spray:
dosage: 15,75 mg every 6–8 hours (one spray into 1 nostril).
Maximum dose: 4 doses per day (63 mg).
What happens if i miss the dose?
If you are almost due for your next dose, skip the missed dose. Never take two doses of the same medicine at once.
What happens if i overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Avoid getting the medication in your eye. Rinse your eyes with water or a saline solution if this happens. If you experience eye irritation that lasts more than an hour, call your doctor. Avoid alcohol. Alcohol can increase the risk of stomach bleeding.
Take sprix only if you have not taken aspirin or any other nsaids. They may contain ingredients similar to ketorolac. These medicines may contain similar ingredients to ketorolac, such as aspirin or ibuprofen. Ketoprofen and naproxen.
Side effects of Sprix
If you experience symptoms of an allergic reaction (hives or difficulty breathing) or a severe reaction on your skin (fever, sore mouth, burning eyes, pain in the skin, or a red or purple rash with blisters or peeling), then seek emergency medical attention. If any of these symptoms present themselves, seek emergency medical assistance immediately.
If you experience any of the following symptoms, stop using sprix immediately and contact your doctor.
- Any skin rash;
- High blood pressure; severe headache; blurred vision or pounding in the neck and ears.
- Heart problem: rapid weight gain and a feeling of shortness of breath.
- Kidney disease: little or no urine, swelling of the feet or ankles, and feeling tired or breathless;
- Liver problem: nausea; upper stomach pains; itching and fatigue; flu-like symptoms. Dark urine. Jaundice.
- Anemia (low red blood cells), pale skin, unusual fatigue, feeling lightheaded or short of breath, cold hands or feet;
- Signs of stomach bleeding include bloody or black stools, bloody vomit, or bloody phlegm.
Some of the common side effects associated with sprix include:
- Nausea and stomach pain.
- Diarrhea, constipation;
- Slow heartbeats
- Reduced urination
- Abnormal liver function tests
- Increased blood pressure
- You may experience pain or irritation in your nose.
- Runny nose;
- Watery eyes
- Throat irritation;
There may be other side effects. For medical advice on side effects, call your doctor. The fda can be contacted at 1-800-fda-1088 to report side effects.
Interaction with other drug
It is sometimes not safe to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, which can increase side effects and make them less effective.
Before using sprix, ask your doctor if you are taking an antidepressant. Certain antidepressants may cause you to bruise or bleed easily.
Tell your doctor about your other medications, including:
- Lithium;
- Methotrexate;
- A blood thinner warfarin coumadin jantoven
- Heart or blood pressure medications, including diuretics or "water pills";
- Seizure medicine: carbamazepine, phenytoin
This list is incomplete. Ketorolac may interact with other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all drug interactions.
