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Generical name: sarecycline SAR-e-SYE-kleen SAR-e-SYE-kleen [SAR-e-SYE-kleen]
Class of drugs: tetracyclines

What is Seysara?

Seysara (sarecycline) is a class of drugs known as tetracycline antibiotics. Sarecycline helps fight acne by killing bacteria that cause pores to become infected and reducing a specific natural oily substance that can cause acne.Seysara is a prescribed medicine that is used to treat serious skin vulgarization in both children and adults who are over 9 years old.

Antibiotics like Seysara are not effective for colds, flu, or any other viral illnesses. The use of antibiotics in situations where they are not required increases the risk of contracting an infection that will resist antibiotic therapy.


Antacids that contain magnesium, aluminum, calcium, or laxatives that contain magnesium and iron-based products can hinder sarecycline's effectiveness, making it less efficient. Use Seysara 2 hours prior to or 6 hours after having calcium supplements, antacids, and laxatives that contain magnesium. Consume Seysara 2 hours prior to or 4 hours following iron preparations and vitamin supplements that contain iron.

Inform your doctor. If you've ever suffered from intracranial hypertension (pseudotumor cerebri, high pressure within the skull, which can cause headaches, blurred vision, and double sight decreases, as well as other signs),

Prior to use this drug

It is not recommended to use Seysara when you have an allergy to sarecycline or other similar medicines such as demeclocycline, minocycline, doxycycline, or tigecycline.

To ensure that Seysara is safe for you, ask your physician if you've previously had:

  • Diarrhea or stool that is watery
  • Issues with vision.

The use of Seysara during pregnancy could impact the development of bones and teeth for the baby who is not yet born. Taking this medicine in the second or third trimester of pregnancy could result in permanent discoloration of teeth later in life. Consult your physician if you are pregnant or planning to be pregnant.

Sarecycline could be absorbed by the milk of your baby and cause harm to the nursing infant.Breastfeeding mothers should avoid taking this medicine.It could be more difficult to become pregnant if you're using this medicine.

Similar/related drugs

Doxycycline, Clindamycin topical, Topical Erythromycin, Tetracycline, and Tazorac

How to take Seysara?

Use Seysara exactly as directed by your physician. Follow the instructions on the prescription label and also read the medication guide or instructions sheets.Take Seysara every day, whether or not you eat, and with a glass full of water.Medication may cause diarrhea. Consult your physician when you experience diarrhea that is bloody or watery.

If you take more than the prescribed dose, it won't increase the effectiveness of this medication; it could cause severe adverse consequences.Use this medicine even if your symptoms do not improve. Dosing too much can make your illness more resistant to treatment. Seysara is not a treatment for the symptoms of a virus (flu or general cold).Keep it at room temperature, free of heat and moisture.

Details on dosage

Usual Adult Dose for Acne:

Weight range: 33–54 kilograms 60 mg taken orally at least once per day
Weight range of 55–84 kilograms: 100 mg taken orally at least once per day
Weight between 85 and 136 kg, 150 mg, orally, twice per day
Use: To treat lesions that cause inflammation in mild to moderate skin vulgaris

Usual Pediatric Dose for Acne:

9 years old or older:
Weight range: 33 to 54 kilograms: 60 mg every day
Weight range: 55–84 kilograms 100 mg oral at least once per day
Weights: 85 to 136 kg; 150 mg taken orally, at least once per day.
Use: To treat lesions that cause inflammation in mild to moderately severe acne vulgaris

What happens if I miss the dose?

As soon as the medication arrives, take it immediately. However, do not take any missed doses if you are close to the time of the next dose. Don't take two doses at a time.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects of this medication on your body. Your reaction could be affected.Seysara can cause your skin to burn more quickly. Avoid tanning beds or sunlight. Protect yourself with protective clothes and sunblock (SPF 30 or more) whenever you're outside.

Side effects of Seysara

Take immediate medical attention. If you are experiencing symptoms of an allergic reaction, Seysara: hives; difficulty breathing; and swelling of your lips, face, and tongue.

Seysara may cause serious side effects. Contact your physician immediately. If you suffer from:

  • A feeling of lightheadedness that makes you feel like you're about to pass out.
  • Extreme stomach pain; diarrhea that's bloody or watery (even when it happens several months after the previous dose);
  • Vertigo (spinning sensation);
  • Increased pressure inside your skull causes severe headaches, hearing ringing, and dizziness. Nausea, eye problems, eye pain.

Seysara's common side effects can include nausea.This isn't a complete list of possible side effects, and other side effects could be present. Consult your physician to seek medical advice on the effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Discuss with your doctor any other medications you take, particularly:

  • Antacids that include magnesium, calcium, or aluminum
  • A mineral supplement containing iron;
  • Medicine used to stop blood clots, such as alteplase, warfarin, enoxaparin, apixaban, dipyridamole, clopidogrel, and other medications, such as ticlopidine;
  • An antibiotic penicillin, such as ampicillin, amoxicillin, amoxil, augmentin, timentin, and many others.
  • Other acne medications: acitretin and isotretinoin.

This is not a complete list, and a variety of other medications could be incompatible with sarecycline.This includes medications both prescription and over-the-counter, vitamins, and herbal products. There are many possible interactions between drugs that are listed here.



Prescription only

Pregnancy & Lactation

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