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[Name of generic: cinacalcet] sin-ah-CAL-set sin-ah-CAL-set“sin-ah-CAL”
Drug class: calcimimetics

What is Sensipar?

Sensipar reduces the concentrations of parathyroid hormone (PTH) and calcium and phosphorus in the body.Sensipar can be used in the treatment of the condition of hyperparathyroidism (overactive performance of parathyroid glands) in patients who are on dialysis for kidney diseases.

Sensipar can also be used to combat high levels of calcium (high concentrations of calcium present in the blood) in patients suffering from tumors of parathyroid glands and also in those who have parathyroid glands that are overactive and are not able to be surgically treated.


There is no need to use Sensipar if you suffer from lower levels of calcium in your blood (hypocalcemia).Before taking Sensipar, inform your doctor whether you suffer from high blood pressure, heart disease, failure, a heart rhythm disorder, liver disease, or any past history of seizures.Sensipar can be effective if consumed before or right after eating food. Be careful not to break or crush tablets. Suck the tablet in whole.

Consult your physician immediately when you notice an adverse reaction that is serious, such as numbness, tingly sensations around your mouth, rapid or slow heart rate, muscle tension or contraction, hyperactive reflexes, seizures, feeling breathless, swelling and weight gain that is rapid, or feeling that you may be able to pass out.To ensure Sensipar can help your health, your blood might need to be checked frequently. Visit your doctor regularly.

Prior to use this drug

There is no need to take Sensipar in the event that you are sensitive to cinacalcet or if you suffer from:

  • Low levels of calcium in your blood (hypocalcemia).

To ensure Sensipar is suitable for you, inform your doctor if you've previously had:

  • Blood pressure that is low or high;
  • Heart disease heart failure, heart disease, rhythm disorder
  • Family or personal or familial history of QT syndrome;
  • A stomach ulcer or severe vomiting;
  • Liver disease;
  • Seizures;
  • If you suffer from kidney disease but are not taking dialysis,

It is unclear if Sensipar could affect a newborn baby. Consult your physician if you are expecting or planning to be pregnant.

It isn't known if the cinacalcet is absorbed into breast milk or if it is harmful to the nursing infant. Do not breastfeed during the time you take this medication.Sensipar does not have FDA approval for use by anyone who is younger than

Similar or related drugs

Prednisone, dexamethasone, reclast, decadron, denosumab, Zometa, and cinacalcet

How to take Sensipar?

Use Sensipar exactly as directed by your physician. Be sure to follow all instructions listed on your prescription label. Your doctor may change your dosage to ensure you are getting the best outcomes. Avoid using this medication in smaller or larger quantities or for a longer period than prescribed.

Sensipar is most effective if you take it in conjunction with food or just after a meal.Don't crush or break tablets. Suck the tablet in whole.

To make sure that your phosphorus and calcium levels aren't too low and your blood needs to be tested for 1 week after starting to take Sensipar or at any time you change your dose, It is also possible to have blood tests regularly while you are taking the medication.Place it in a cool, dry place far from light, moisture, and heat.

Details on dosage

Usual Adult Dose for Secondary Hyperparathyroidism:

Initial dosage: 30 mg orally daily (cinacalcet is recommended to be titrated not more often than every 2–4 weeks using successive doses of 30 60, 60 90, 120, 180, and 30 mg taken orally daily).
Maintenance dosage of between 30 and 180 mg taken orally every day
Maximum dose: 180 mg once a day.
The indication for approval is secondary hyperparathyroidism among patients suffering from chronic kidney disease who are on dialysis.

Usual Adult Dose for Hypercalcemia and Malignancy:

Initial dosage: 30 mg daily, orally. (Titrate dosage every two to four weeks) through successive doses of 30 mg a day, 60 mg twice a day, 90 mg twice every day, and 90 mg 3 or 4 times a day.
Dosage maintenance: 60 mg to 360 mg taken orally per day
Maximum dose: 90 mg four times a day.
An approved indication is: parathyroid cancer and primary hyperparathyroidism sufferers who are not able to undergo parathyroidectomy.

Usual Adult Dose for Primary Hyperparathyroidism:

Initial dose: 30 mg taken orally twice daily (titrate dosage every two to four weeks) through a series of dosages of 30 mg per day, 60 mg twice per day, 90 mg twice every day, and 90 mg three or four times a day.
Dosage for maintenance 60-360 mg to 360 mg orally every day
Maximum dose: 90 mg four times a day.
An approved indication is: parathyroid cancer and primary hyperparathyroidism patients who cannot be treated with parathyroidectomy.

What happens if I miss the dose?

Do the dose you missed as soon as you can remember. Do not take your missed dose if it's nearing the time for the next dose. Don't take any extra medication to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Helpline at 1-800-222-1222.

What should be avoided?

Follow your doctor's advice regarding food, drinks, food, or any activity.

Side effects of Sensipar

See a doctor immediately. If you are experiencing symptoms of an allergic reaction to Sensipar: symptoms of hives; difficulty breathing or swelling of your lips, face, or tongue

Contact your doctor immediately. If you suffer from:

  • The sensation of tingling or numbness is felt within your mouth.
  • Muscular pain, tightness, or contraction
  • A seizure (convulsions);
  • Breathing shortness (even when exercising) swelling rapidly, gaining weight;
  • Indications that stomach blood is bleeding bleeding, bloody, or tarry stools, the spit-up of blood, or vomiting that appears like coffee grounds
  • Lower levels in the blood of calcium and a tingling or numbness sensation in your mouth, a rapid and slow heart rate, muscle contraction, tightness, or hyperactive reflexes.

Common Sensipar side effects could include:

  • Nausea, vomiting;
  • Headache, fatigue;
  • Low blood pressure
  • Reduced appetite
  • The hands, legs, or feet.

This isn't a complete list of possible side effects, and others could happen. Consult your physician for advice regarding medical adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Many medications can be incompatible with cinacalcet. This includes over-the-counter and prescription supplements, vitamins, as well as herbal supplements. The interactions of all potential medications are mentioned in this medication guide. Discuss with your doctor the medicines you are taking or will start or stop taking in the course of treatment with Sensipar. Make a list of all the medicines you take for any healthcare professional who cares for you.



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