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Generic name: acetaminophen and oxycodone [a-SEET-a-MIN-oh-fen-and-OX-i-KOE-done]
Drug class: narcotic analgesic combinations

What is Endocet?

andEndocet is a mixture of acetaminophen with oxycodone. Oxycodone is a painkiller.  aSometimes, an opioid is referred to as a narcotic. Acetaminophen is a less powerful pain reliever, which increases the effects of oxycodone.Endocet is a medication used to alleviate mild to severe pain.The drug can be used for other purposes not mentioned in this medication guide.

Side effects of Endocet

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, Endocet: hives; breathing difficulties; swelling of your lips, face, and tongue.In rare instances, acetaminophen could cause a serious skin reaction, which can cause death. This could occur regardless of whether you've previously used acetaminophen and did not experience any reaction. Stop taking Endocet and consult your doctor immediately in the event of the appearance of a skin rash or redness that spreads and leads to blistering as well as peeling.Oxycodone could reduce or stop your breathing and even cause death. A person caring for you should administer Naloxone or seek medical attention if you experience breath that is slow, with pauses for long periods or blue-colored lips, or if it is difficult to get up.

Contact your doctor immediately. If you suffer from:

  • Sighing, noisy breathing, deep breathing, breathing that stops when you sleep;
  • An euphoric feeling, similar to what you've passed out;
  • The mind, or unusual thoughts or behaviors;
  • Seizure (convulsions);
  • Urinary problems;
  • Infertility, missed menstrual periods;
  • Impotence, sexual issues, and a loss of interest in sexual activity;
  • Liver issues nausea, abdomen pain or itching weight loss, black stools, dark urine jaundice (yellowing of the eyes or skin);
  • Low levels of cortisol nausea nausea or loss of appetite. Fatigue, dizziness, or worsening weakness;
  • Serotonin levels are high within the body, causing hallucinations, agitation, sweating, fever, rapid heart rate, shivering muscles, stiffness, twitching, and loss of coordination. Vomiting, nausea, and diarrhea.

Breathing problems that are serious could be more prevalent for older people and those who suffer from debilitation, wasting syndrome, or chronic breathing conditions.

Common endocet adverse effects are:

  • Headache, drowsiness, tiredness;
  • Nausea, vomiting, stomach pain, constipation;
  • Blurred vision
  • Dry mouth.

This is not a comprehensive list of possible side effects, and other side effects could occur. Consult with your physician regarding medical effects. Report any potential side effects to the FDA at 1-800-FDA-1088.


It is not recommended to make use of Endocet in the event that you've recently consumed alcohol or other sedatives, tranquilizers, or other opioid drugs.Oxycodone can slur or stop breathing and can cause habit-forming.dosage Use only your prescribed dosage, and take the entire pill to avoid a potentially fatal dose. Do not share Endocet with a different person.A MISUSE OF THIS MEDICINE could result in addiction, overdosing, or even death, particularly in children or another patient who is taking the medication without a prescription.Don't take more of this medication than is suggested. A high dose of acetaminophen could harm your liver or even cause death. Contact your physician immediately in case you experience nausea or stomach pain and itching, decreased appetite, dark urine, yellowish or clay-colored stool, or jaundice (yellowing of your eyes or skin).Oxycodone can cause withdrawal symptoms that could be life-threatening for babies in the event that the mother takes Endocet while pregnant.Acetaminophen overdose may damage your liver or result in the death of a person.urine, Call your doctor immediately if you nausea,nausea discomfort in stomach,ch and itching, a lack of appetite, black stools, dark urine or jaundice (yellowing of your eyes or skin).Do not take this medication and contact your doctor immediately if you notice the appearance of a rash or redness on your skin, which spreads and causes blisters as well as peeling.The risk of fatal side effects could be experienced if you take the medicine in conjunction with alcohol or other substances that can cause drowsiness or slow breathing.

Similar or related drugs

aspirin, acetaminophen, tramadol, duloxetine, naproxen, oxycodone, and tylenol

Before you take this drug

You shouldn't make use of Endocet if you have an allergy to acetaminophen (Tylenol) and oxycodone or if you suffer from:

  • Your asthma or breathing issues have left you in significant discomfort.
  • You have a blockage within your stomach or intestines, which includes paralytic ileus.
  • You've recently consumed alcohol, tranquilizers, sedatives, or any other opioid medication.

Certain medications can react with oxycodone, causing serotonin syndrome. Check with your doctor to see if you are also taking medication for mental illness, depression, or Parkinson's disease. They can also treat severe infections, migraines, or prevent vomiting and nausea. Talk to your doctor prior to making any changes in the way or how often you take your medicines.

To be sure Endocet is suitable for you, inform your physician if you suffer from:

  • breathing issues sleep apnea
  • Alcoholism, liver disease, or cirrhosis, or if you consume regularly;
  • A history of substance abuse or alcohol addiction is a mental illness.
  • Kidney disease, urinary tract problems;
  • Issues with your gallbladder, thyroid, pancreas, or adrenal gland
  • An injury to the head or brain, tumors, seizures,
  • If you are using any sedative, such as valium (diazepam alprazolam, ativan, lorazepam klonopin, restoril, tranxene, versed, xanax, and many others),

Endocet is more likely to cause breathing issues in people over the age of 65 and those who are extremely sick, malnourished, or otherwise weak.

If you take oxycodone during pregnancy, the baby may become dependent on that substance. This can cause severe withdrawal symptoms for the infant after it is born. Babies who develop dependence on the drug that causes habit formation may require medical treatment for a period of time. Do not feed your baby while taking this medication.Acetaminophen and oxycodone can be absorbed through breastmilk and cause harm to a nursing infant. Inform your doctor if you are nursing your baby.

How to take Endocet?

Use Endocet as directed. Follow the directions on the prescription label. Oxycodone could reduce or stop breathing, especially when you first begin using the drug or change your dosage. Do not take Endocet in greater quantities or for longer than the time prescribed.An overdose can damage your liver or even lead to fatality. Inform your doctor if you have a strong urge to take more of this medication.Oxycodone could be addictive, even in high doses. Don't share Endocet with any other person, particularly one with a previous history of addiction or abuse. A MISUSE OF OPIOID MEDICINE could lead to addiction, overdose, or even death, especially in children or another user of the medication without a prescription. Selling or giving the gift of Endocet is illegal.If you are undergoing surgery, inform the surgeon in advance that you're using Endocet. It is possible that you will need to stop using the drug for a brief period of time.Don't stop taking this medication suddenly following the duration of use, or you could experience uncomfortable withdrawal symptoms. Discuss with your physician how you can effectively stop using the medication.Keep Endocet in the room at a temperature that is away from heat and moisture. Be aware of the quantity of medicine consumed in each bottle. Oxycodone can be abused, and you must be aware of anyone taking your medication improperly or without a prescription.Don't keep any of your leftover Endocet tablets. Consult your pharmacist on how you can find a drug disposal program. If there's no take-back program, flush the unneeded tablets down the drain.Do not crush or break the Endocet tablet so that you can inhale it or mix it with a liquid so that you can inject this drug directly into your vein.

What happens if I miss the dose?

Because Endocet is a medication to treat pain, you're likely not to skip a dose. Avoid any missed doses in the event that it is near the time to take your next dose.Take no extra medication in an attempt to make up for a missed dose.

What happens if I overdose?

For medical emergencies, seek immediate attention. You can also make a call for help at the Poison Helpline at 1-800-222-1222. A high dose of this medication can be fatal, particularly in children or anyone else who is taking the medication without a prescription. Overdose symptoms may include vomiting, nausea, sweating, extreme dizziness, aplenty of pupils, as well as slow or not breathing.The doctor might suggest that you take Naloxone (a medication to treat an overdose of opioids) and carry it in your bag throughout the day. The person who is caring for you could give you medication if you are unable to breathe or do not wake up. Your caregiver needs to get medical attention in the event of an emergency. They might need to administer CPR (cardiopulmonary resuscitation) to you as they wait for assistance to arrive.Naloxone can be purchased from the local pharmacy or health department. Be sure that anyone who cares for you understands where you store naloxone and how to utilize it.

Interaction with other drug

Opioids may interact with other medications and cause dangerous adverse effects or even death. Be sure your doctor is aware if you take:

  • Other opioids: prescription cough medicine
  • Medications that induce sleep or cause breathing to slow, like a sleeping pill, muscle relaxer, sedative tranquilizer, antipsychotic medication,
  • The drugs you take affect serotonin levels in your body. This is medicine for Parkinson's disease, depression, migraine headaches, serious infections, or the prevention of vomiting and nausea.

This list isn't complete. Other medications can interact with oxycodone or acetaminophen, such as prescription and over-the-counter supplements, vitamins, and herbal products. The interactions of all potential types aren't mentioned in this medication guide.



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NDC 60951-712-70, Endocet, 10 mg / 325 mg, side 1 is E 712,