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Savella

The generic name is milnacipran milnacipran mil-NA. Si-pran mil-NA-si-pran
Drug class: serotonin-norepinephrine reuptake inhibitors

What is Savella?

Savella alters the chemical levels within the brain that are known as neurotransmitters. A change in these chemical levels is believed to be linked to the condition known as fibromyalgia (a medical disorder that creates chronic pain in joints and muscles).

Savella isn't intended to treat depression, but it performs the same way as certain antidepressants do.Savella is used to treat constant pain that is caused by the condition known as fibromyalgia (a medical disease that causes chronic discomfort in joints and muscles).

Warnings

Do not take Savella. If you've used an MAO inhibitor within the last 14 days, including isocarboxazid linezolid methylene blue injections, phenelzine rasagiline and selegiline, as well as tranylcypromine, When you stop using milnacipran, you must be patient for at least 5 days before taking an MAOI.

There will be times that you consider suicide at as soon as you start using Savella in particular if are younger than old. Older. Your doctor should examine you regularly, at the very least for the first 12 weeks of the treatment.

Inform your doctor about any new or worsening symptoms, for example, changing your behavior or mood, such as anxiety, panic attacks, or trouble sleeping. You should also tell your doctor about the feeling of being angry, irritable, impulsive, or aggressive. Anxious, hyperactive (mentally as well as physically), or depressed, or you are thinking about suicide or harming yourself.Do not drink alcohol when taking Savella. This can increase the chance of sustaining liver damage.

Inform your physician if you frequently use other medicines that cause you to sleep (such as allergy or cold medication, sedatives, opioid pain medication, sleeping medications, muscle relaxers, and medications to treat depression, seizures, and anxiety). They may contribute to the sleepiness triggered by Savella. Milnacipran can affect your thinking or reaction. Be aware if you are driving or doing any other activity that requires you to be vigilant.Savella is not allowed to be used by anyone under 18 years of age.Stop taking Savella without consulting your physician.

Similar or related drugs

Prednisone, duloxetine, pregabalin, Cymbalta, Lyrica, and Deltasone

Prior to use this drug

It is not recommended to utilize Savella in case you have an allergy to milnacipran.Savella shouldn't be given to children younger than 18.

To be sure Savella is suitable for you, ask your doctor if you previously had:

  • Liver disease;
  • Kidney disease;
  • Heart disease and excessive blood pressure;
  • Seizures or epilepsy;
  • Bipolar disorder (manic depression);
  • Bleeding issues;
  • Low levels of sodium in your blood.
  • Sexual issues;
  • When you drink alcohol
  • If you are taking a blood thinner like warfarin (Coumadin, Jantoven),

Make sure to inform your doctor that you are taking medication that is a stimulant, opioid, herbal product, or medication to treat mental illness, depression, Parkinson's disease, migraine headaches, serious infections, or for the prevention of vomiting and nausea. These medications may be incompatible with milnacipran and can cause serotonin syndrome, a serious illness.

Many young people are prone to thoughts of suicide after they first start taking Savella. Your doctor should be able to check your progress regularly. Family members and other caregivers should be on the lookout for changes in your symptoms or mood.

Pregnancy-related use of this medication could cause lung problems or other problems for the infant. Contact your doctor immediately when you find yourself pregnant. Do not begin stopping or even stop using this medication during your pregnancy without the advice of your doctor.

If you're pregnant and you are a registered mother, your name could be added to an OB-GYN registry to track how Milnacipran affects you, the infant.It is not suggested to breastfeed while taking this medicine. Consult your physician about any potential risks.

How to take Savella?

Use Savella exactly as directed by your physician. Follow the directions on your prescription label, and review all medication guides and instructions sheets. The doctor might change the dosage of your medication. Consult your physician If you are experiencing an increase in need to take more medicine.You can take medication with or without food; however, food can assist you in taking the medication more effectively.Your heart rate and blood pressure must be checked regularly.

Inform your doctor if there are any changes in your sexual function, such as a loss of interest in sexual activity, having trouble with an orgasm, or (in males) issues with erections or ejaculation. Certain sexual issues are treatable.

Don't stop taking Savella abruptly, or you may experience painful withdrawal signs. Discuss with your doctor the best way to stop taking this medication.Maintain it at room temperature, clear from moisture and heat.

Dosing information

Usual Adult Dose for Fibromyalgia:

Dosage maintenance: 50 mg orally two times per day.
Maximum dosage: 100 mg orally 2 times per day (200 mg taken orally daily).
Comments:
Dosing can be adjusted according to the following guidelines:
Initial dose on day 1: 12.5 mg orally once
Days two and three: 12.5 mg orally, 2 times per day.
Days 4–7: 25 mg taken orally two times per day.
After 7 days: 50 mg orally, two times per day.
Use: Treatment of fibromyalgia

What happens if I miss the dose?

You should take the medication as quickly as you are able, but avoid your missed dosage if you are nearing the time to take the next dose. Don't have two doses at one time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

Overdose symptoms can include severe drowsiness, a low heart rate, and a weak pulse. It can also cause weak breathing and fainting (breathing might cease).

What should be avoided?

Avoid driving or engaging in hazardous activities until you understand the effects of this medication on your body. The way you react could be impaired.

Do not drink alcohol.

Consult your physician before taking a nonsteroidal anti-inflammatory medicine (NSAID) like Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. When you take an NSAID together with Savella, it can cause bleeding or bruises easily.

Side effects of Savella

See a doctor immediately. If you are experiencing symptoms of an allergy reaction, Savella: hives, breathing difficulties, or swelling of your lips, face, and tongue

Inform your doctor about any new or deteriorating symptoms, including a change in your mood or behavior such as mood swings, anxiety, panic attacks, trouble sleeping, or if you are feeling angry, irritable, impulsive, or aggressive. Active, restless (mentally and physically), or are having thoughts about taking your own life or harming yourself.

See your doctor right away in the event that you are suffering from:

  • Very little or no urine;
  • Blurred vision blurred vision, tunnel vision, eye swelling or pain, the appearance of halos around lights
  • A seizure;
  • The sensation of being lightheaded as you're passing out;
  • Liver issues stomach discomfort (upper right side) itching bloody urine; jaundice (yellowing of the eyes or skin);
  • Low sodium levels low sodium level, headache and confusion, severe fatigue, vomiting, trouble with memory or thinking, and feeling unstable;
  • Mad episodes: racing thoughts, higher energy levels, unusual risk-taking behaviors, extreme happiness, anger, or arousal.

Get medical attention immediately. If you experience indications that suggest serotonin syndrome, for example, hallucinations, agitation, sweating or shivering, an increase in heart rate, muscle stiffness and twitching, loss of coordination, nausea, vomiting, or diarrhea,

Certain side effects are more prevalent in older people.

Common Savella side effects may include:

  • Nausea, vomiting, constipation;
  • Dry mouth;
  • Raised blood pressure.
  • Rapid heartbeats or fast beats;
  • Increased sweating and flushing (warmth or redness) or a tingly feeling
  • Headache, dizziness
  • Trouble sleeping.

This is not a comprehensive list of possible side effects, and other side effects could be present. Contact your doctor to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

The use of Savella, along with other medicines that cause you to become drowsy, could cause more drowsiness. Consult your physician before taking opioids, sleeping pills such as a muscle relaxer, or medication for seizures or anxiety.

Other medications can be incompatible with milnacipran, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your physician your current medications and any medication you begin or stop taking.