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Generic name: sarecycline [SAR-e-SYE-kleen]
The brand name is Seysara.
Dosage format: oral tablet (100 mg; 150 mg; and 60 mg)
Class of drugs: tetracyclines

What is Sarecycline?

Sarecycline is a medication used by adults and young children over the age of 9 to treat a variety of acne.Sarecycline is also employed for reasons not mentioned in this medication guide.

Side effects of Sarecycline

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as difficulty breathing, hives, and swelling of your lips, face, and throat,

Sarecycline can cause severe adverse effects. Contact your doctor immediately if you suffer from:

  • A feeling of lightheadedness that makes you feel like you're passing out;
  • Intense stomach pains; diarrhea that is bloody or watery (even when it happens several months after your most recent dose);
  • Vertigo (spinning sensation);
  • An increase in pressure within the skull, causing severe headaches, ringing in the ears, dizziness, nausea, eye problems, and eye pain.

Common side effects can include nausea.

This is not a comprehensive list of all side effects. Other side effects could occur. Consult your doctor for medical advice about adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.


Only use it according to the directions. Talk to your doctor if you take other medications or suffer from any other medical condition or allergies.

Prior to use this drug

Do not use sarecycline in the event that you are allergic to sarecycline or other similar drugs like demeclocycline, minocycline, doxycycline, or tigecycline.

Tell your physician if you had any of the following:

  • Diarrhea or fluid-filled stools
  • Issues with vision.

Sarecycline taken during pregnancy could affect the bone and tooth development of the infant. Taking this medicine in the third and second trimesters of pregnancy may result in permanent discoloration of teeth later in life. Consult your physician if you are expecting or planning to be pregnant.

Sarecycline may be absorbed into the breastmilk of a baby and could harm nursing babies.It is not advised to use this medication when you are breastfeeding.It could be more difficult for you to become pregnant if you're taking this medication.

How to take Sarecycline?

Follow the directions on the label of your prescription and read the medication guide or instructions sheets. Make sure you use the medication exactly as prescribed.Dose sarecycline at least once a day, with or without food and a large drink of water.Medication may cause diarrhea. Inform your doctor in the event that you suffer from diarrhea that is bloody or watery.

Doing more than your recommended dosage will not increase the effectiveness of this medication and could result in severe adverse effects.

Continue to take this medication even if your symptoms do not improve. Inadequate doses can make your disease immune to medications. Sarecycline is not a treatment for the symptoms of a virus (the flu or a common cold).Make sure it is kept at room temperature, clear of moisture and heat.

Details on dosage

Usual Adult Dose for Acne:

Weight range: 33–54 kilograms; 60 mg every day, once
Weight range of 55–84 kilograms: 100 mg at least once per day
Between 85 and 136 kilograms, 150 mg, orally, twice every day
Use: To treat inflammatory lesions in mild to severe facial acne.

Usual Pediatric Dose for Acne:

Age 9 or over:
Weight 33–54 kilograms: 60 mg at least once per day
Weight range: 55–84 kilograms 100 mg oral at least once per day
85-136 kg, 150 mg of oral medication at least once per day
Use: To treat lesions that cause inflammation in moderate to severe non nodular acne vulgaris

What happens if I miss the dose?

You should take the medication as quickly as you are able, but avoid your missed dosage if you are close to the time of the next dose. Don't have two doses at one time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of how sarecycline affects you. The way you react could be affected.

Sarecycline may cause the skin to burn more quickly. Avoid tanning beds and sunlight. Protect yourself with protective clothes and apply sunblock (SPF 30 or greater) whenever you're outside.

Interaction with other drugs

Discuss with your physician any other medication you use especially:

  • Antacids that include magnesium, calcium, or aluminum
  • A mineral supplement containing iron;
  • Medications used to stop blood clots: apixaban, alteplase, warfarin, enoxaparin, dipyridamole, ticlopidine, and more
  • Other acne medications—acitretin and isotretinoin.

This list isn't complete, and other medications may influence sarecycline. This includes over-the-counter and prescription medications, vitamins, and herbal products. The interactions of all drugs are included here.



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