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Generic name: Sacrosidase [sak-ROE-si-dase]
Name of the brand: Sucraid
Dosage form: Oral solution (8500 intl. Units/ml)
Drug class: Digestive enzymes

What is Sacrosidase?

Sacrosidase is an enzyme derived from yeast that replaces an enzyme known as sucrase that is produced by the body. Sucrase assists the body in breaking down and processing sugars in digestion. If you are deficient in this enzyme, sucrase, the sugar could be absorbed into the intestines, where it interacts with bacteria. This can lead to gas, bloating, stomach pain, and fluid-like vomiting.

Sacrosidase can be used to treat sucrase deficiencies that occur in individuals who suffer from congenital sucrase-isomaltase deficiencies (CSID). CSID is a genetically-related enzyme deficiency, and sacrosidase is not able to treat this condition.

Use sacrosidase only for treating any health issue that has not been evaluated by your physician. Sacrosidase is not recommended for treating general indigestion or stomach disorders triggered by other illnesses.Sacrosidase is also employed for other purposes that are not covered in this guideline.

Side effects of Sacrosidase

Contact a medical professional immediately. If you notice any of the following symptoms, warning signs of reactions to an allergen, such as hives: difficulty breathing and swelling of your lips, face, tongue, throat, or face,

Sacrosidase may cause serious side effects. Contact your doctor immediately in the event that you experience:

  • Worsening stomach pain, nausea, vomiting, or diarrhea;
  • Experiencing extreme thirst or heat, feeling very thirsty or hot, not being able to urinate, sweating heavily, or having dry and hot skin.

A few of these side effects could be signs that you have a CSID condition, but not the actual adverse effects of sacrosidase.

Common adverse effects of sacrosidase include:

  • Stomach pain, mild nausea;
  • Mild diarrhea and constipation
  • Sleep problems (insomnia);
  • Headache
  • Nervous sensation.

This isn't an exhaustive list of all the side effects. Others could happen. Consult your physician to seek medical advice on the effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.


Sacrosidase may trigger an allergic reaction. Contact a medical professional immediately. If you experience any of the following symptoms or warning signs of reactions to an allergen: hives; trouble breathing or swelling of your lips, face, tongue, throat, or face

Before you take this drug

This medication is recommended if you have an allergy to yeast, yeast-related items, glycerin (glycerol), as well as papain (Accuzyme, Ethezyme, Gladase, Kovia, and others).

To ensure that sacrosidase is safe for you, consult your doctor if you suffer from an illness like diabetes. Sacrosidase alters the way that your body absorbs sugar, and your blood sugar levels can alter. Your doctor will inform you whether any of your medication dosages should be adjusted.

FDA pregnancy category C. It isn't known whether sacrosidase can cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to get pregnant while taking this drug.Inform your doctor if you are nursing a child when you are taking sacrosidase.

How to take Sacrosidase?

Follow the directions on the prescription label. Take sacrosidase only in smaller or larger quantities or for longer than the recommended time.Sacrosidase often triggers an extremely allergic reaction. Before starting the medication, the doctor may suggest an examination of your skin to make sure that you're not averse to sacrosidase.

Your doctor might administer your first dose of this medication in a clinic or hospital setting to swiftly deal with any adverse side effects that may occur. An extreme allergic reaction may be experienced, which requires immediate medical attention.

Sacrosidase is generally taken at every meal or snack. It is recommended to take a portion of the dose as soon as you eat and then consume the remaining half after eating or having a snack.The medication comes with instructions on safe and effective use. Follow these guidelines carefully. Consult your physician or pharmacist for any additional concerns.

Make sure you measure your dosage by using the scoop that comes with sacrosidase. Clean and then dry your scoop following each use.The liquid of Sacrosidase should mix with between 2 and 4 ounces of milk, water, or formula for babies that isn't more than the temperature of the room. Do not mix it with hot or warm liquids, or the medication won't be as efficient.Don't mix sacrosidase and juice from fruit or drink juice when you are taking the medicine.

Sacrosidase could be part of a full program of treatment, which also includes a specific diet. Follow the diet plan developed by your physician or nutritionist. Learn about the list of foods that you should avoid in order to manage your health condition.

Place these medicines in your refrigerator. Avoid freezing. Keep away from sunlight. Make sure the bottle is tightly shut when not in use.The first time you open a sacrosidase container, write your date and time on the bottle. Discard any sacrosidase that is not used four weeks after opening the bottle.

Sacrosidase dosing information

Usual Adult Dose for Sucrase-Isomaltase Deficiency:

Up to 15 kg, 1 milliliter (8500 international units), or 1 full measuring scoop or 28 drops taken orally at mealtime or snack
More than 15 kg Over 15 kg: 2 ml (17,000 international units) or 2 scoops of measuring capacity or 56 drops orally every meal or snack
Comment: Half of the dose should be administered at the time of a meal or snack, with the remaining dose administered during the snack or meal.
Utilization of oral replacement therapy to treat sucrase deficiency that is genetically determined for patients suffering from congenital sucrase Isomaltase deficiency (CSID)

Usual Pediatric Dose for Sucrase-Isomaltase Deficiency:

5 months or older:
Up to 15 kg 1 milliliter (8500 international units) or 1 scoop of measuring capacity or 28 drops per meal or snack
More than 15kg: 2 ml (17,000 international units) or 2 full measuring scoops or 56 drops of liquid orally at mealtime or snack
Comment: Half of the dose should be administered at the time of the meal or snack, and the other half during the meal or after a snack.
Utilization of oral replacement therapy to treat sucrase deficiency in genetically determined patients suffering from CSID

Do I be concerned if I miss a dose?

You should take the missed dose as soon as you can remember. Do not take any missed doses if you are nearing the time for the next dose. Don't take additional medicine to make up for the missed dose.

What will happen if I take excessively?

The overdose of sacrosidase is not likely to cause symptoms.

What should be avoided?

You might need to stay away from eating a large amount of starch (found mostly in potatoes, rice, corn, and pasta, along with bread). Be sure to follow your doctor's advice on any diet you should follow when you're taking sacrosidase.

Follow the instructions of your physician regarding any other food restrictions or beverages when you are taking sacrosidase.

Interaction with other drugs

Other medications can interfere with sacrosidase, such as prescription and non-prescription medicines, vitamins, and products made from herbs. Be sure to inform your health professionals about any medications you take in the present and any medication you stop or start using.