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Generic name: for levonorgestrel: emergency contraceptive [LEE-voe-nor-jes-trel]

Brand names include: AfterPill (brand), Curae (brand), EContra EZ (brand), EContra One-Step (“EContra One-Step”), Fallback Solo (“Fallback Solo”),… Show all 16 brands.
Drug class: contraceptives

What is React?

React can be used to prevent pregnancy following unprotected sexual activity or when other methods of contraception have failed (such as condoms breaking or two or more pills not being taken).This medication guide does not list all possible uses for React.

Side effects of React

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: difficulty breathing, hives, swelling of the face, lips, or throat.If you experience severe pain on your side or lower stomach, call your doctor immediately or go to an emergency room. This could indicate a tubal (a pregnancy that implants in the tube of the fallopian tubes instead of in the uterus) pregnancy. A tubal pregnancy can be a medical emergency.

React can cause the following side effects:

  • Stomach pain;
  • Breast pain or tenderness
  • Nausea, vomiting, diarrhea;
  • Headache, dizziness;
  • Feeling tired or
  • Changes in your menstrual cycle

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.


React does not terminate a pregnancy if an egg fertilized has already been attached to the uterus.Before taking levonorgestrel, ask your doctor or pharmacist if you are regularly using medication to treat seizures, HIV/AIDS, or tuberculosis. Other medicines may make levonorgestrel ineffective.

Before you take this drug

React is not meant to be used as a regular form of birth control. Speak to your doctor about all the different birth control options available.This medicine should not be used if you have already become pregnant. Reacting does not stop a pregnancy that is already underway.No one under the age of 17 is allowed to use this product.If you have an allergy to levonorgestrel, then it is best not to use this drug.Before taking levonorgestrel, tell your doctor or pharmacist if you are regularly using medication to treat seizures, tuberculosis, or HIV/AIDS. Levonorgestrel can be less effective when used as an emergency contraceptive if you are taking certain medications.Levonorgestrel can slow down breast milk production. Inform your doctor if breastfeeding is a concern.

How to take React?

Follow the instructions on the label or those prescribed by your doctor.It is important to react as soon as possible (no more than 72 hours) after unprotected sexual activity.If you vomit after 2 hours of taking React, call your doctor immediately. Do not take a second dosage without consulting your doctor first.You may be pregnant if your period is more than a week late. If you think you're pregnant, take a pregnancy test. Contact your doctor. React does not terminate pregnancy when the fertilized ovary has already attached to the uterus.A doctor should confirm within 3 weeks of taking React that you are not pregnant and that the medicine hasn't caused any adverse effects.Store away from heat and moisture at room temperature.

What happens if I miss the dose?

React does not require a daily dosage schedule because it is only used in a single dose.

What happens if I overdose?

React comes in a single tablet of a specific strength. This means that an overdose will be unlikely if the levonorgestrel dose is taken as prescribed. Take no more than one tablet simultaneously.

What should be avoided?

React does not protect against sexually transmissible diseases, including HIV and AIDS. The only way to prevent these diseases is by using a condom. Avoid unprotected sexual activity.

Interaction with other drug

Some medications may make React less efficient, which can lead to pregnancy. Ask your doctor or pharmacist about the safety of React if you take any of these medications.

  • Efavirenz;
  • Rifampin;
  • Seizure medication: carbamazepine, felbamate, fosphenytoin, phenobarbital, phenytoin, and primidone.

This list is incomplete. Levonorgestrel may be affected by other drugs, such as vitamins and herbs. This list does not include all possible interactions with other drugs.