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Generic name: Saliva substitutes [sa-LYE-va-substi-tutes]
Brand names: Aquoral, Biotene Dry Mouth, Biotene Moisturizing Mouth Spray, Biotene Mouthwash, Biotene Oral Balance,… show all 22 brands
Class of drugs: Products for the mouth and throat

What is Moi-Stir?

Moi-Stir is a man-made version of mucus, which normally occurs in the mouth. The medicine helps produce artificial saliva when your body doesn't make enough.

Use Moi-Stir to relieve discomfort and dry mouth caused by medications, surgical or radiation treatments, and chemotherapy treatments.

Moi-Stir can be used in other ways not mentioned in the medication guide.

Side effects of Moi-Stir

If you experience difficulty breathing, hives, lips, face, throat or tongue swelling; any of the following could indicate an allergy: difficulty in taking deep breaths; swelling around lips, face throat or tongue and difficulty swallowing

There may be other potential side effects, and for medical advice on them please speak to your healthcare provider or contact the FDA at 1-800-FDA-1088.


There are a variety of brands and types of substitutes for saliva on the market. This leaflet does not list all the brands. Please follow all instructions on the label or package of your medication.

Before you take this drug

Moi-Stir should be avoided if any ingredient listed on the package is allergenic.

Consult your doctor if you're pregnant or breastfeeding before using Moi Stir.

Similar/related drugs

pilocarpine, chlorhexidine topical, topical glycerin, Peridex, topical sodium hyaluronate, Salagen, and Biotene Mouthwash

How to take Moi-Stir?

Use a saliva substitute only for the mouth. Avoid getting it into your eyes.

Follow the instructions on your product's label or your doctor’s prescription.

The Moi-Stir works inside the mouth and is not intended to be swallowed.

Use the liquid Moi-Stir or oral rinse by swishing a little in your mouth and spitting it out after 30 seconds.

Before using the oral powder, it must be mixed with 1 ounce (25 ml) of water. Use the mix immediately, no matter how many times you have to stir it. The mixture should not be saved for future use.

Before each use, shake the oral spray gently and spray it directly in your mouth.

Even while sleeping, you can hold the tablet or lozenge in your mouth for a long time. To help keep the tablet in place, some tablets can be pressed against your gums or teeth.

You can apply the gel, paste, or swabs directly to the teeth, gums, or sides of your mouth. Please follow all the instructions.

The frequency of use depends on the condition you have or your schedule for taking medication.

Moi-Stir is usually used three to five times a day, or when your mouth feels uncomfortable and dry. During chemotherapy or radiotherapy, this medication may be used up to 10 times per day. Please follow all instructions for dosage.

Moi-Stir should not be used by children without supervision.

Moi-Stir is only one part of an overall treatment plan that may include other methods for oral hygiene. You should follow your doctor’s advice.

Storing your substitute saliva according to the instructions on the label is important. Keep away from moisture, heat, and light.

What happens if I miss the dose?

Moi-Stir is used as needed and may not have a schedule. Use the missed dose if you have a regular schedule as soon as possible. If your next dose is coming due, take the extra one without delay. You should not take extra medication to compensate for a missed dose.

What happens if I overdose?

Overdosing on a substitute for saliva is unlikely to cause harm. If you accidentally swallowed a large amount of the product, call 1-800-222-1222 or seek emergency medical care.

What should be avoided?

After using Moi-Stir, you may have to wait 15 minutes before eating or drinking. Please abide by all instructions on the label.

If the substitute saliva gets into your eyes, rinse with water.

Interaction with other drug

Moi-Stir is not affected by other medications that you may take orally, inject, or swallow. Many drugs interact.Inform all healthcare providers of any medicines you are taking, such as prescriptions and over-the-counter remedies, vitamins, and herbs.