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Generic Name: Etelcalcetide [E-tel-KAL-se-tide]
Drug Class: Calcimimetics

What is Parsabiv?

Parsabiv is used to treat overactive parathyroid glands (hyperparathyroidism) in adults with chronic kidney failure who are on dialysis.

Parsabiv can also be used to treat conditions that are not mentioned in this medication guide.

Side effects of Parsabiv

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, and throat,

Parsabiv could cause severe adverse effects. Consult your doctor immediately if you suffer from:

  • A seizure (convulsions);
  • Breathlessness (even at moderate exertion), swelling, and rapid weight gain.
  • Irregular heartbeats;
  • Low levels of calcium—muscle spasms or contractions, numbness, or tingly sensation (around your mouth or on your toes and fingers)
  • Symptoms of stomach bleeding, such as bloody or black stools, coughing up blood, or vomit that resembles coffee grounds.

Common negative side effects of Parsabiv can include:

  • Tingling or numbness;
  • Muscle spasms,
  • Low calcium
  • Headache
  • Nausea, vomiting, and diarrhea.

This isn't a complete list of all the side effects. Other side effects could occur. Consult your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Prior to receiving Parsabiv, be sure to inform your doctor that you've had cinacalcet in the last seven days.

Before you take this drug

You shouldn't be treated with Parsabiv if you are allergic to it.

Tell your physician if you had any of the following:

  • Congestive heart failure;
  • Abdominal bleeding or stomach;
  • A seizure;
  • Lengthy QT syndrome (in either you (or a relative)
  • If you've used an ingredient called cinacalcet (Sensipar) in the last seven days,

It is unclear if Parsabiv can harm an unborn baby. Consult your physician if you are expecting or planning to become pregnant.

It is not recommended to breastfeed during the course of this medication.

How to take Parsabiv?

Parsabiv is administered as an infusion into the vein. Your healthcare professional will offer you this injection as part of your dialysis treatment.

Parsabiv is typically administered three times a week, at the end of dialysis.The doctor could alter your dosage or schedule.

There is a chance that you will need frequent medical tests. Even if there are no symptoms, tests can help your doctor determine whether this medication is working.

What happens If I miss a dose?

Since you'll be receiving Parsabiv in a medical setting, you're not likely to skip the dose.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

The overdose can cause the calcium levels to go too low. The symptoms include muscle cramps, nervousness, and numbness or the sensation of tingling.

What should be avoided?

Follow the doctor's advice regarding any limitations on foods, drinks or any activity.

Interaction with other drugs

Other medications that can influence Parsabiv include prescription and non-prescription medicines, vitamins, and herbal products. Inform your physician about the medicines you are currently taking and any medications you begin or stop taking