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Generic name: pimozide [PIM-oh-zide]
The class of drug: miscellaneous antipsychotic agents

There is no evidence that the Orap brand name has been taken off the market within the U.S. If there are generic versions of this item that were approved by the FDA, there may be substitutes that are similar to the original.

What is Orap?

Orap operates by altering the chemical actions in the brain.Orap is prescribed to those suffering from Tourette's syndrome. It reduces the physical (motor) and vocal (phonic) manifestations of tics when the symptoms hinder daily living.

Orap is not to be used to treat motor tics that are not triggered by Tourette's syndrome.Orap can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Orap

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, and swelling of your lips, face, and tongue.

Long-term use or high doses for long periods of time of pimozide can result in a severe movement disorder that cannot be reversed. The longer you are using Orap, the more likely you are to suffer from this disorder, especially when you are older.

Orap can cause severe adverse reactions.

 Consult your physician immediately. If you suffer from:

  • muscles that are not controlled in your facial muscles (chewing or lip smacking, frowning, tongue movements, blinking, or eye movements);

  • rapid or pounding heartbeats, a fluttering chest, shortness of breath, and a sudden feeling of dizziness (like you're going to faint);

  • fever, chills, tiredness, mouth sores, and skin sores;

  • a seizure (convulsions);

  • Extreme nervous system reaction: very rigid (rigid) muscles with high fever, sweating, and confusion; rapid or irregular heartbeats as if you're about to be stricken with a stroke.

Common adverse consequences of Orap can include:

  • issues with vision or speech;

  • Drowsiness; trouble sleeping;

  • Feeling agitated;

  • tight muscles;

  • constition 

  • Dry mouth.

This isn't a complete list of all the side effects. Others could happen.


Consult your physician to seek medical advice on the effects.


You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Do not take Orap in the case of long QT syndrome, low levels in your blood of magnesium or potassium, or if you use any medication that may cause the occurrence of tics (such as stimulants and ADHD medications).

Discuss with your doctor all the medicines you are currently taking and all the ones you will begin or stop taking.


Many medications can trigger serious medical issues when taken together with Orap.

Prior to using this drug

It is not recommended to use this medicine if you're allergic to Orap or any other antipsychotic medications, or if

  • Your blood levels are low in magnesium or potassium.

  • You suffer from long QT syndrome (in the case of you or an immediate family member). You have long QT syndrome.

  • If you are taking medications that create tics, like stimulants and ADHD medications (Adderall, Ritalin, and a few others).

Certain medications can trigger unwanted or harmful effects when taken in conjunction with Orap.


Your doctor could alter the treatment regimen if you make use of:

  • ADHD medicine;

  • An anti-microbial or antifungal medicine;

  • anti-psychotic medication;

  • An antidepressant

  • antiviral drugs to treat the symptoms of hepatitis C as well as HIV;

  • anti-malaria medication;

  • Heart rhythm medication

  • medication to treat or prevent the symptoms of nausea as well as nausea and vomiting (such as Zofran);

  • "triptan" migraine headache medication (such as Imitrex or Maxalt) (or

  • Opioid medication.

Inform your doctor if you have ever suffered from:

  • Liver disease;

  • kidney disease;

  • seizures or epilepsy;

  • heart conditions, high blood pressure, or heart problems, high blood pressure, or cardiac attack;

  • an increased prostate or urinary issue;

Utilising Orap during the last three months of pregnancy could result in problems for the infant, including withdrawal symptoms, breathing difficulties, and feeding issues such as tremors, agitation, arousal, and stiff or limp muscles.


You may also experience withdrawal symptoms or other complications if you discontinue taking the medication during your pregnancy.


You should not discontinue taking the medication without consulting your physician.

Breastfeeding is not advised when using Orap.Orap is not a product that has been approved for use by anyone less than 12 years old.

How to take Orap?

Follow the directions on the prescription label and go through all medication guides or instructions.


The doctor might change the dosage.


Make sure you take the medication precisely as directed.

Consult your doctor if you have a stomach ache or diarrhea.


It is possible that you will develop an electrolyte imbalance that can cause heart rhythm issues during your treatment with Orap.

It may take a while before you notice an improvement in your symptoms.


Use the medication exactly according to the directions, and inform your physician if your symptoms don't improve or if they worsen.

Your physician will monitor your health frequently.


The function of your heart may have to be assessed with an electrocardiograph, also known as an ECG (sometimes known as the EKG).

Keep at room temperature, away from heat, humidity, and light.

Be careful not to stop taking Orap abruptly, or you may be suffering from withdrawal symptoms.


Consult your physician about how to stop using Orap.

What happens if I miss the dose?

You should take the medication as quickly as you are able, but avoid your missed dose if it's nearing the time to take the next dose.


Don't take two doses at a time.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

The symptoms of an overdose can be muscle stiffness, slow breathing, or feeling lightheaded.

Aviod this

Avoid driving and other hazardous activities until you understand how Orap can affect you. Your reaction could be affected.

Alcohol consumption can cause an increase in certain adverse effects associated with pimozide.Grapefruit can react with Orap and cause unwanted negative side effects. Beware of grapefruit-related products.

Interaction with other drug

Orap could cause grave heart problems. Your risk of developing heart problems is greater in the event that you take other drugs for illnesses such as asthma, heart issues such as high blood pressure, depression, the disease odepressionmalaria, or HIV.

The use of Orap along with other medicines that cause drowsiness can increase the severity of this effect.


Talk to your doctor prior to using opioid medication, a sleeping pill such as a muscle relaxer, or medicine to treat an anxiety disorder or seizures.

A variety of drugs can impact Orap, and certain drugs shouldn't be used simultaneously.


Discuss with your doctor all the medicines you are currently taking and all the medicines you begin or stop taking.


This includes over-the-counter and prescription medicine, vitamins, and herbs.


The interactions between these products are not included in this list.