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Generically: Olanzapine (oral) (oral) Oh-LANZ-a-peen [ oh-LANZ-a-peen
Brand Names: ZyPREXA, ZyPREXA Zydis
Dosage Forms: Oral tablet (10 mg; 15 mg; 2.5 mg; 20 mg; 5 mg; 7.5 mg); oral tablet, disintegrating (10 mg; 15 mg; 20 mg; 5 mg).
Drug Class: Atypical antipsychotics

What is Olanzapine?

Olanzapine is an anti-psychotic medicine that is utilized to manage psychotic disorders like schizophrenia and bipolar disorder (manic depression) in adults as well as children aged 13 or older.

Olanzapine can also be used in conjunction with the medication fluoxetine (Prozac) to treat symptoms of depression in children and adults who are at least 10 years old and suffer from bipolar I disorder.Olanzapine can also be used for reasons not mentioned in this guideline.

Side effects Of Olanzapine

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as difficulty breathing, hives, or swelling of your lips, face, and tongue,Get medical attention when you experience a severe drug reaction that affects the body's many organs. Symptoms may include symptoms like skin eruptions, fever, and swollen glands. Other symptoms include muscle aches, extreme weakening, unusual bruising, or the appearance of yellowing on the eyes or skin.

Long-term use or high doses of olanzapine could cause serious movement disorders that may not be reversible. The longer you take Olanzapine, the more likely you are to suffer from this disorder, particularly in the case of women or older people.

Olanzapine may cause serious side effects. Contact your doctor immediately in the event of:

  • Muscles that are not controlled in your facial muscles (chewing or smacking your lips, frowning, tongue movements, blinking, or eye movements);
  • Difficulty swallowing or speaking;
  • Swelling of your feet or hands
  • Insomnia, strange thoughts or behavior, hallucinations, or thoughts of harming yourself
  • low white blood cell count—fever, chills, mouth ulcers, and skin sores pain in the throat, coughing or breathing problems, feeling lightheaded,
  • Symptoms of signs of dehydration—feeling hot, thirsty, or hot; not being able to flush or sweat heavily; excessive sweating; or dry and hot skin;
  • Liver issues: upper stomach pain, itching, weight loss, dark urine, stools that are clay-colored, jaundice (yellowing of the eyes or skin);
  • High blood sugar—increased thirst, more frequent appetite, urination, dry mouth and breath odor that is fruity, drowsiness, dry skin, blurred vision, losing weight,
  • Extreme nervous system reaction: very rigid (rigid) muscles and sweating; high fever; confusion; quick or uneven heartbeats; and a feeling that you could faint.

Common adverse effects of olanzapine could include:

  • Weight increase (more likely to occur in teens) and increased appetite
  • Headache, dizziness, fatigue, drowsiness, or restlessness.
  • Issues with memory or speech;
  • Tremors or shaking; the sensation of being tingly or unresponsive;
  • Changes in personality
  • Dry mouth or more salivation;
  • Stomach discomfort, constipation,
  • Discomfort in your arms or legs.

This isn't a complete list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Olanzapine is not permitted for use by older adults suffering from dementia-related psychosis.

Before you Take this Drug

Olanzapine is not a good choice when you have an allergy to it.Olanzapine can cause an increase in the likelihood of dying in people suffering from psychosis related to dementia and is not authorized for this purpose.

Inform your doctor if you were ever diagnosed with:

  • Liver disease;
  • Coronary disease, either high blood pressure or high blood pressure;
  • The highest cholesterol or triglycerides
  • A stroke, including "mini-stroke";
  • Breast cancer;
  • A seizure;
  • Alzheimer's disease;
  • Diabetic and high blood sugar
  • An increased prostate;
  • Bowel problems,
  • Narrow-angle glaucoma.

Antipsychotic medication taken during the last three months of pregnancy could result in breathing issues or feeding problems. It could also cause withdrawal symptoms in newborns. If you get pregnant, tell your doctor right away. Don't stop using Olanzapine without the advice of your physician.

Olanzapine is a drug that can be absorbed through breastmilk. If you're breastfeeding, inform your doctor when you experience extreme fatigue, irritability, or drowsiness. issues, tremors, or abnormal movement of the muscles in your nursing infant.The tablet that dissolves orally (Zyprexa Zydis) could contain the chemical phenylalanine. Consult your physician if you suffer from phenylketonuria (PKU).

How to take Olanzapine?

Follow all the instructions on the label of your prescription and study all medication guides or instruction sheets. The doctor might change your dosage. Make sure you take the medication exactly as prescribed.Olanzapine may be used without or with food.

Discard an oral breaking tablet (Zyprexa Zydis) from the container only after it is time to consume the medication. Place the tablet in your mouth and let it disintegrate without chewing. Drink several times until the tablet disintegrates.Olanzapine could cause the blood sugar to be high (hyperglycemia). If you're diabetic and have blood sugar issues, you should check your levels regularly.You could gain weight or have high levels of cholesterol and triglycerides (types of fat) while taking olanzapine, especially if you're an adolescent. You might require periodic blood tests.Consult your physician if your symptoms don't improve or if they become worse when you take the drug olanzapine.

Do not stop taking Olanzapine abruptly, even if you are well. The sudden stop can result in serious adverse side effects.Olanzapine is often used in conjunction with other antipsychotic drugs and an antidepressant. Take all medications according to the directions, and carefully read the medication guide that you receive. Do not alter your dose or dosing schedule without a doctor's approval.

The medication may only be part of a full program of treatment that includes counseling as well as other psychological support programs. Follow the instructions of your physician.Maintain at room temperature, free of heat, moisture, and light.

What Happens if I Miss the Dose?

Do not take the medicine for as long as you can. However, do not take any missed doses if you are nearing the time to take the next dose. Don't take two doses at once.

What Happens If I Overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

The symptoms of an overdose can include the feeling of drowsiness, agitation, anger, slurred speech, confusion, an increase in heart rate, uncontrolled or jerky muscle movements, difficulty breathing, and the feeling of fainting.

What Should be Avoided?

Avoid driving and other hazardous activities until you understand the effects of olanzapine. Drowsiness or dizziness can lead to accidents, falls, or even serious injuries.Do not get up too quickly from a lying or sitting position. You could be dizzy.Do not drink alcohol. Dangerous side effects can be experienced.

Beware of becoming dehydrated or overheated. Take plenty of water, particularly in hot weather or during exercise. It is much easier to get extremely dehydrated and overheated while taking olanzapine.

Interaction with Other Drugs

Combining olanzapine with other medicines that cause you to sleep or cause your breathing to slow down could result in life-threatening or dangerous negative side effects. Ask your doctor before taking any opioid medications, such as a sleeping pill, muscle relaxer, or medication to treat anxiety and seizures.

Other drugs can interact with the effects of olanzapine.This includes prescription and over-the counter medications, vitamins, as well as herbs. Inform your physician about all the medicines you are currently taking and any medication you begin or stop taking.



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