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Name of the Generic: Naxitamab [ max-IT’-a-man [ max-IT-a-man
Brand Name: Danyela
Dosage Format: Intravenous solution (gqgk 4 mg/mL)
The Class of Drug: Miscellaneous antineoplastics

What is Naxitamab?

Naxitamab is a treatment for highly-risk neuroblastoma (a rare type of cancer) in adults and children who are at least one year old.

Naxitamab is used in conjunction with another medication that causes your body to create certain blood cells that can help combat cancer and protect your body from infections.Naxitamab is administered following treatment for cancer that has not worked or stopped working.

Naxitamab is approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, certain people showed a response to naxitamab; however, further studies are required.Naxitamab is also employed for other purposes that are not covered in this guideline.

Side effects of Naxitamab

See a doctor immediately. Get medical attention immediately if you notice symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, or swelling of your lips, face, and tongue.

There are some side effects that can happen when you inject. Contact your physician when you feel dizzy, lightheaded, itchy, warm, short of breath, tingly, or if you suffer from symptoms such as a cough, loud breathing, or a swelling on your face.

Naxitamab may cause serious side effects. Contact your doctor immediately in the event that you experience:

  • Intense pain throughout your body.
  • Numbness, tingling, and burning sensations in your feet or hands;
  • Extreme headache and confusion. It can cause issues with thinking, weakness, and loss of vision.
  • A seizure;
  • Uncomfortable or difficult to urinate;
  • Symptoms of a cold—such as a stuffy or runny nose, sneezing, sore throat, cough, or lower fever—and feeling not well.
  • Eye issues: blurred vision, trouble focusing, dilated pupils unbalanced pupil size, becoming more sensitive
  • High blood pressure—headache, nausea, vomiting, vision changes, dizziness, chest pain, nosebleeds, rapid or pounding heartbeats beating in your ears or neck,
  • Low blood cell counts, fever, chills, fatigue, oral sores and skin sores easily bleeding, unusually pale skin, cold feet and hands, and feeling lightheaded or sluggish

The treatment for cancer may be delayed or discontinued permanently when you experience certain adverse consequences.

Common adverse effects of naxitamab could include:

  • Nausea,  vomiting, diarrhea, and inability to eat;
  • Low blood cell count or any other abnormal lab tests;
  • Skin, or itchy hives.
  • Swelling;
  • Headache, fever, fatigue, or feeling ill;
  • High heart rate;
  • Experiencing anxiety or irritation;
  • Cough
  • Swelling, pain, bruises, or irritation in the area at the site of injection.

It isn't a complete overview of the various negative side effects. Other effects may also be present. Contact your physician for advice regarding medical adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Related drugs

  • Cisplatin,
  • Doxorubicin,
  • Vincristine,
  • Adriamycin,
  • Dinutuximab,
  • Platinol


Naxitamab may cause serious adverse effects. Call your doctor immediately if you notice an intense headache, pain or tingling sensation, weak speech, trouble with or thinking, vision issues or pain in the urinal, fast or rapid chest pains, or seizures.

Inform your doctor if you experience any of the following side effects following the injection: being lightheaded or dizzy, itching, sensations of warmth or tingling, shortness of breath or loud breathing, or a swelling of your face.

Before you take this drug

It is not recommended to treat with naxitamab if you are sensitive to it.Inform your doctor if you are ever diagnosed with hypertension.You might need to undergo an ultrasound test that is negative prior to commencing this treatment.

Do not take Naxitamab when you are expecting. It could harm the unborn baby. Utilize the most effective contraception to stop pregnancy while taking the drug and for at least two months following the last dose.Avoid breastfeeding while taking this medication and for at least two months after the last dose.

How to take Naxitamab?

Naxitamab is administered as an infusion into the vein. The healthcare professional will give the injection.The medicine should be administered slowly, and the infusion may take between 30 and 60 minutes to finish.

Naxitamab is typically administered in the form of a 28-day treatment regimen, repeated every four or eight weeks. It is possible that you will need to take this medication only for the first week of every cycle.The doctor who prescribes you the medication will determine what time period you'll receive this medicine.

There are other medicines to avoid severe adverse side effects or an allergic reaction. Continue to take these medications for the time your physician has prescribed.You will be monitored closely for a minimum of 2 hours after receiving the injection to ensure that there isn't an allergic reaction or other negative side effects.

It is possible that you will require frequent blood tests to ensure that the medication isn't causing negative consequences. Your blood pressure will require regular monitoring.

What happens If I miss a dose?

Consult your physician for treatment in the event that you don't make an appointment to have your naxitamab injection.

What happens If I overdose?

Because naxitamab can only be administered by a health specialist in a medical setting, it is not likely that an overdose will occur.

What should be avoided?

Follow the doctor's advice regarding any limitations on foods, drinks, or any activity.

Interaction with other drugs

Other medications can affect naxitamab. These include prescription and over-the-counter medications, vitamins, and herbal products. Discuss with your doctor the medicines you are currently taking as well as any medications you are about to start or stop taking.