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Generic Name: Nesiritide [ness-EAR-a-tide]
Drug Class: Vasodilators

What is Natrecor?

Natrecor reduces blood vessel dilation, relaxes it, and lowers blood pressure.Natrecor is a medication used to help improve breathing for people who have sudden, severe heart failure.Natrecor is administered via injection into an intravenous (IV) injector and/or infusion.


It is not recommended to take Natrecor when you have extremely high blood pressure or if your heart can't pump blood efficiently.Before receiving Natrecor, inform your doctor that you suffer from kidney disease.

Inform your physician about any heart issues you are experiencing or have had before. Certain heart problems can make it unsafe for you to get Natrecor.

Before you take this drug

It is not recommended to treat with Natrecor in the event that you are allergic to nesiritide or

  • The heart isn't able to pump blood correctly.
  • You have extremely high blood pressure, but you are very

Speak to your doctor if you have ever had kidney problems.

Consult your physician if you are expecting. It's not clear if Nesiritide could cause harm to a newborn baby. But heart failure may become more severe during pregnancy and can lead to complications like premature birth, stillbirth, or the death of the mother. The advantages of treating heart failure could outweigh the risk for the child.

It isn't known if the nesiritide is absorbed into breast milk or whether it is harmful to the nursing infant. Consult your physician if you are breastfeeding a child.

Similar/related drugs

How to Take Natrecor?

Natrecor is administered as an injection into the vein. Your healthcare provider will offer the injection.

The medicine should be administered slowly, and the infusion can be administered repeatedly for up to 96 hours.Your blood pressure, as well as other vital indicators, will be closely monitored.

Details on dosage

Usual Adult Dose for Congestive Heart Failure:

The initial dose is a 2 mg/kg IV bolus and then 0.01 mg/kg/min by continuous IV infusion. to be adjusted more frequently than every 3–4 hours, to a maximum of 0.03 mg/kg/min.
This drug should not be started at a dose greater than the dose recommended for initial use.
The loading dose might not be appropriate for patients who have a systolic blood pressure lower than 110 mmHg or for patients who have been treated recently by afterload reducers.
There is limited information on administering this medication for more than 96 hours. - Be sure to monitor the blood pressure while administering.
Use: To treat heart failure that is acutely decompensated in patients suffering from hyperpnea in a calm state or who have little activity.

What happens If I miss a dose?

Since you'll receive Natrecor in a setting that is clinical, you will not be able to skip the dose.

What happens If I overdose?

Because this medication is administered by a medical expert in a medical environment, it is not likely that an overdose will occur. But if you take too much medication, you might be ill.

What should be avoided?

Do not get up too quickly from a lying or sitting position. You could get dizzy.

Side effects of Natrecor

Take immediate medical attention in the event that you exhibit symptoms of an allergy reaction, such as hives, breathing problems, or swelling of your lips, face, or tongue.

Contact your family members immediately. If you suffer from:

  • A feeling of lightheadedness, as if you're about to pass out
  • Very little or no urine.

Common Natrecor adverse effects could include:

  • Dizziness;
  • Nausea;
  • Headache
  • Back pain.

It's not a comprehensive description of the various negative results. There are other effects that could be observed. Ask your doctor for guidance on medical side effects. It is possible to report any adverse reaction to FDA by calling 1-800-FDA-1088.

Interaction with other drugs

Other medications can interfere with nesiritide. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor all your medications currently in use as well as any medications you are about to start or stop taking.