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Mitigare

Brand names: Colcrys and Mitigare
Drug Class: Antigout agents

What is Mitigare?

Miigare reduces inflammation and pain by changing the way your body reacts to crystals of uric acid.

Mitigare, which was created before federal regulations that required FDA approval of all drug products marketed by companies, has not been used in all approved ways.

The FDA has approved the Colcrys brand colchicine to prevent or treat gout and to treat a genetic disorder called familial Mediterranean fever among adults and children over 4 years of age.

The FDA approved Mitigare colchicine to treat flare-ups of gout in adults.

Colchicine generics are used for treating or preventing gout attacks, as well as to relieve symptoms associated with Behcet's syndrome (such as swelling, heat, inflammation, or pain).

It is important to note that Mitigate does not cure gouty arthritis or Behcets syndrome. Nor will it stop the progression of these conditions. It is not recommended to use this medicine as a pain reliever for any other condition.

This medication guide does not list all possible uses of Mitigare.

Side effects of Mitigare

If you experience any of the following symptoms of an allergy reaction, seek immediate medical attention: difficulty breathing, hives, swelling in your lips, face, throat, or tongue.

It is possible that Mitigare can cause severe side effects. If you experience:

  • Muscle pain or weakness;
  • Numbness in the fingers and toes.
  • Your lips, hands, and tongue may appear pale or gray.
  • Severe or ongoing vomiting or diarrhea;
  • Flu symptoms typically include fever, chills and body aches.
  • Feeling weak, tired, or bruising easily?

Some of the common side effects that mitigare can cause include:

  • Nausea, vomiting, and stomach pain;

There may be other side effects. For medical advice on side effects, call your doctor. Call the FDA's hotline, 1-800-FDA-1088, to report adverse reactions.

Similar/related drugs

ibuprofen, naproxen, methylprednisolone, colchicine, Advil, Medrol, and Colcrys

Warnings

When certain medications are taken with Mitigare, they can cause serious drug interactions. Inform your health care providers of all the medicines that you are currently using, as well as any new medications you may start taking.

Before you take this drug

If you have an allergy to Mitigare, then it is best not to use the product.

Certain medicines may cause dangerous or unwanted effects when combined with Mitigare. This is especially true if your doctor has prescribed any of these drugs.

  • Cyclosporine;
  • Nefazodone;
  • Tipranavir;
  • Clarithromycin, or telithromycin.
  • Itraconazole or ketoconazole;
  • Hiv or aids medication: atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir or saquinavir.

Tell your doctor about any of the following to ensure Mitigare will be safe for you:

  • Liver Disease

  • Kidney disease
  • If you are taking digoxin or a cholesterol-lowering medication,.

There is no way to know if Mitigare can harm an unborn child.Inform your doctor immediately if you intend to become pregnant.

Breast milk can contain colchicine, which may cause harm to a baby who is nursing. Inform your doctor that you are breastfeeding a child.

How to take Mitigare?

Avoid purchasing Mitigare from sellers outside the United States or on the Internet. If you use this medicine incorrectly or against the doctor's advice, it can cause serious side effects and even death.

Do not take this medicine in larger or smaller amounts or for longer than recommended on the label. Take this medication only as prescribed. Do not exceed the recommended dosage or take it for longer than advised.

Take Mitigare with or without food.

Mitigare should be taken as soon as you feel a gouty attack. You may get less benefit from the medicine if you delay taking it.

If you continue to experience gout symptoms, it may be necessary to take another lower dose an hour later. You should follow your doctor's advice.

The reason for taking the medicine will determine your dose. The doses of Mitigare for Mediterranean fever and gout are different.

Even if you are feeling fine, do not stop taking Mitigare without consulting your doctor.

If your symptoms do not improve or worsen, contact a physician immediately.

 

If you take this medication long term, frequent medical tests may be required.

 

Keep the bottle at a temperature that is comfortable for you, away from heat, moisture, and sunlight. When not in use, keep the bottle closed tightly.

What happens if I miss the dose?

As soon as possible, take the missed dose. If your next dose is almost due, do not take the missed one.. You should not take more medicine to compensate for a missed dose.

What happens if I overdose?

Call Poison Help at 1-800-222-1222 or seek emergency medical care. A mitigare overdose can be deadly.

The symptoms of an overdose may include nausea, vomiting, and stomach pain. Other symptoms can be numbness, tingling or numbness, a weak pulse, or a slowed heart rate.

What should be avoided?

Interactions between mitigating and grapefruit juice can cause unwanted side effects. Use grapefruit-based products sparingly while you are taking Mitigare.

Interaction with other drug

Mitigare can cause interactions with many drugs. Some drugs shouldn't be taken together. These include prescription, over-the-counter, herbal, and vitamin products. This medication guide does not list all interactions. Inform your doctor of all the medicines you take, including those that you stop or start using while you are taking this medication. Provide a complete list of your medications to all healthcare providers who treat you.