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What is Mirtazapine?
Mirtazapine can be described as a type of antidepressant. How this medicine works isn't completely understood. The theory is that it will enhance communication between nerve cells within the central nervous system. It may also restore the balance of chemicals in the brain.
Mirtazapine is a medication used to treat major depression disorders in adults.
It's not clear whether mirtazapine is secure and efficient in treating MDD in children.
Warnings
Do not take mirtazapine if you are already taking tryptophan (sometimes also referred to as L-tryptophan).
Avoid using mirtazapine if you've used any MAO inhibitor within the past 14 days. This includes isocarboxazid or linezolid, as well as methylene blue injection, phenelzine, other tranylcypromine, and so on.
Many people are contemplating suicide after taking their first antidepressant. Your physician will examine your progress regularly at appointments while taking mirtazapine. Families or other caregivers must be aware of changes in your mood or signs.
Don't give this medication to any person younger than 18 years of age without consulting medical professionals. This medication is not a prescription drug for young children.
It can take several weeks for your symptoms to begin to improve. Continue to take the medicine according to the directions, and inform your physician if you persist after four months of therapy.
Alcohol consumption can cause an increase in certain adverse effects associated with mirtazapine.
Mirtazapine can impair your ability to think or react. Take care when driving or performing any other activity that requires you to remain vigilant.
Don't discontinue taking this medication immediately. Consult your physician prior to discontinuing this medication.
Before you take this drug
It is not recommended to take this drug if you are sensitive to mirtazapine.
Don't take mirtazapine in the event that you've used or taken an MAO inhibitor within the last 14 days. An adverse drug interaction may be observed. MAO inhibitors can include isocarboxazid linezolid and methylene blue injection the phenelzine and tranylcypromine as well as other MAO inhibitors.
To ensure this medication is suitable for you, inform your doctor if previously had:
- Lower white blood cell counts;
- Glaucoma;
- Kidney or liver disease
- Low sodium levels in your blood.
- A seizure;
- Depression, suicidal ideas, or suicidal thought or behavior;
- Bipolar disorder (manic depression) for the family members of you;
- Stroke or heart issues
- High cholesterol or triglycerides
- Long qt syndrome (in the case of you or a relative);
- Low blood pressure.
Check with your physician whether you are also taking medication that is a stimulant or opioid, herbal products and medicines to treat mental illnesses such as depression, Parkinson's disease, migraine headaches, and serious infections, or treatment for nausea or vomiting. The medicines can be in a relationship with mirtazapine and can cause serotonin syndrome.
Many young people are prone to thoughts of suicide after they first start taking antidepressants. The doctor you see should be able to check your progress on a regular basis. Family members and other caregivers need to be on the lookout for any changes in your symptoms or mood.
Consult your physician if you are nursing or pregnant.
The tablet that dissolves orally could include phenylalanine, which could be hazardous if you have the condition known as phenylketonuria (PKU).
Mirtazapine has not been permitted for use by any person who is younger than.
How to take Mirtazapine?
Follow the exact dosage as directed by your physician. Be sure to follow the directions on your prescription label and review all drug guides and instructions sheets. The doctor might change the dose you take.
Use the medication throughout the day, preferably at night.
Use the usual tablet type of mirtazapine and water.
Mirtazapine can be taken either with or without meals.
Discard an orally disintegrating tablet from its packaging only after you're ready to consume the medication. Put the tablet under your tongue and let it disintegrate, avoiding chewing. Drink several times while the tablet disintegrates.
It could take several weeks for the symptoms to get better. Continue to take the medicine according to the directions, and inform your physician if you don't improve after 4 days of medication.
Stop using mirtazapine at once, or it could cause unpleasant reactions (such as nausea, dizziness, vomiting, agitation, nervousness, sweating, numbness sensations, tingling, or electrical sensations of shock). Discuss with your physician how you can completely stop taking this medication.
Keep at room temperature, free of heat, moisture, or sunlight.
Details on dosage
Usual Adult Dose for Depression:
The first dose is 15 mg once orally, every night at bedtime
Dosage for maintenance: 15 to 45 mg taken orally, once per day.
Maximum dose: 45 mg/day
Comments:
The dose may be increased each 1 to 2 weeks until a maximum dosage of 45 mg/day is reached based on the patient's responses.
Patients should be evaluated regularly in order to determine if they require continuing use of the drug.
Treatment for severe depression
What happens if I miss the dose?
Do not take the medication as fast as you can. However, do not take the missed dose when it's almost time for the next dose. Take two doses simultaneously.
What happens if I overdose?
For medical emergencies, seek emergency treatment or dial the poison help line toll-free at 1-800-222-1222.
Some symptoms of overdose include memory loss, confusion, sleepiness, and rapid heart rate.
What should be avoided?
Consuming alcohol while taking mirtazapine could result in adverse consequences.
Beware of driving and other hazardous activities until you are aware of the effects this medicine has on your body. The way you react could be affected.
Side effects of Mirtazapine
Take immediate medical attention when you notice indications or warnings of an allergic response to mirtazapine (hives and joint pains or discomfort, difficulty breathing, swelling of your throat or face) or an extreme skin reaction (fever and sore throats, burning eyes, skin discomfort, purple or red skin with blisters, as well as peeling).
If you notice any changes or are getting worse symptoms from your doctor, such as behavioral or mood changes, anxiety, anxiety attacks, or trouble sleeping, or if you are feeling Are You Feeling Abused, Frustrated, Aggressive and Depressed?? Do you find yourself uncontrollably angry, frustrated and aggressive, active yet restless (mentally and physically) and feeling increasingly depressed, contemplating ending your own life or harming yourself? If that is the case for you then seek assistance immediately before it escalates further or threatens self-destruction or harming oneself further.
Contact your physician immediately. If you are suffering from
- Racing thoughts, a decreased necessity for rest, unusual behavior when taking risks or feeling intense happiness or sadness, and being more talkative than usual
- Blindness, blurred vision, swelling, or pain in the eyes, as well as seeing halos of lighting;
- It's like you're about to faint.
- Extremely rash, blisters, or swelling of the fingers or on the toes;
- A seizure;
- Low white blood cells (fever, chills, cough, and sores around the nose or mouth; signs of flu; difficulty breathing);
- Low sodium levels can cause headaches and confusion. It can also cause severe weakness, slurred speech, vomiting, loss of coordination, and feeling unstable.
Get medical attention immediately if you experience signs of serotonin syndrome, like agitation, hallucinations, and sweating. Other symptoms include fever and shivering. You may also experience a rapid heart rate, stiffness of the muscles, or twitching. You may also experience lack of coordination, nausea, vomiting, or diarrhea.
Common mirtazapine side effects include:
- drowsiness, dizziness;
- Increased appetite
- Gaining weight.
This is not an exhaustive listing of all side effects. Other side effects could occur. Contact your physician to seek medical advice on the consequences. It is possible to report any side effects to the FDA at 1-800-FDA-1088.
Interaction with other drug
When you take mirtazapine along with other medicines that cause drowsiness, it can cause more of the same. Consult your physician before taking any opioid medications, sleep medication, relaxation medication, or medicine to treat anxiety and seizures.
Inform your physician about any medications you take currently. A variety of drugs may affect mirtazapine, specifically:
- Cimetidine;
- Diazepam;
- John's wort;
- tramadol;
- tryptophan (sometimes known as l-tryptophan);
- Is an antibiotic; clarithromycin, rifampin, and rifampicin
- Antifungal medicine: itraconazole, ketoconazole;
- Antiviral medication to treat hiv/aids: indinavir, thefinavir, theronavir, and saquinavir.
- Medication to treat mood disorders, thought disorders, or mental illnesses, for example, lithium or various antidepressants and an antipsychotic;
- Migraine medication, migraine headache medicine, sumatriptan, rizatriptan, imitrex, maxalt, and more;
- Seizure medicine: carbamazepine, phenytoin.
The list below isn't complete, and there are many other medications that can interact with mirtazapine. This covers prescription as well as over-the-counter medications, vitamins, and herbs. There are many possible interactions between drugs. are included here.