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Mapap (rectal)

Generic Name: Acetaminophen (rectal) (rectal) a-SEET’a-MIN-oh’fen“a-SEET-aMIN-oh-fen.
Names of Brands: Acephen, Feverall, and Mapap.
Classification of Drugs: Miscellaneous analgesics.

What is Mapap?

Mapap is a pain-relieving medication for fever reduction. Mapap is a suppository for treating numerous conditions, including headaches and muscle pains, arthritis, backaches, toothaches, colds, and fevers. Mapap could also be used to treat conditions that are not mentioned in this guide.

Side effects of Mapap

Seek medical attention immediately. If you are experiencing warning signs of an allergic reaction, such as symptoms of hives, breathing difficulties, or swelling of your lips, face, and throat. In some rare instances, mapap may cause a severe skin reaction that could cause death. This could occur regardless of whether you've previously taken the medicine and experienced no reaction. Stop taking Mapap and consult your doctor immediately if you notice an itch or redness on your skin that spreads, causing blistering as well as skin peeling. If you have the type of reaction described above, then you shouldn't use any medication that contains Mapap. This medication could cause severe adverse consequences. Take this medicine off and contact your doctor immediately if you experience:

  • Nausea, nausea, stomach pain, loss of appetite.
  • Itching, dark urine, stool that is colored with clay.
  • Jaundice (yellowing of the eyes or skin).

More minor side effects might be more likely, or there may be no side effects whatsoever. This is not a comprehensive list of all the side effects. Other effects may also be present. Contact your doctor for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Similar/related drugs

Aspirin, Acetaminophen, Tramadol, Ibuprofen, Cyclobenzaprine, Paracetamol, and Naproxen


Do not take more than what is suggested. A high dose of acetaminophen may damage your liver or result in death. Call your doctor immediately if you experience nausea, discomfort in your stomach area, itching, or a loss of appetite. dark stools, clay-colored urine, and jaundice (yellowing of the eyes or skin). In rare instances, Mapap may cause a severe skin reaction. Stop taking this medication and consult your doctor immediately if you notice the appearance of a skin rash or redness that spreads, causing blisters as well as peeling.

Before you take this drug

It is not recommended to use Mapap if you have an allergy to it. Don't use Mapap without a prescription from a doctor if you've had an alcohol-related liver condition (cirrhosis) or if you consume more than three alcoholic drinks every day. Your doctor will decide if Mapap is suitable for you to use during your pregnancy. Do not take Mapap without the guidance of your doctor if you are expecting. Acetaminophen may pass through breast milk and could cause harm to a nursing infant. Don't take this medication without consulting your physician, whether you are breastfeeding or not. Avoid giving this medication to children without medical guidance.

How to take Mapap?

Follow the directions on the prescription label and study all medication guides or instruction sheets. Your doctor may alter your dosage. Follow the medication precisely as prescribed. Do not take more than is suggested. A high dose of acetaminophen could damage your liver and cause death. When treating children, make sure you use the pediatric version of acetaminophen. Follow the directions on the medication package for dosing. Do not consume the rectal suppository orally. It is intended for use within your rectum. Clean your hands before as well as after having the suppository rectal.

The wrapper should be removed prior to inserting the suppository. Do not handle the suppository for too long, or it may melt in your hands. Place the suppository gently into your rectum, with the pointed end pointed toward the tip first. For the best results, remain on your back for a couple of minutes. The suppository will begin to melt, and you should experience little or no discomfort as you take it. Do not use Mapap and consult your physician in the event:

  • If you are still suffering from an infection after three days of treatment.
  • You still experience the pain after 10 days of treatment (or 5 days if you are treating children).
  • You have a painful throat or a high fever, nausea, and vomiting.
  • You have an itch, a rash, a persistent headache, or any type of swelling or redness.
  • If your symptoms become more severe or if you experience the appearance of new symptoms.

Suppositories for the rectal can be kept in the fridge. Don't allow the medication to become frozen. Keep at room temperature, free of moisture and heat.

 What happens if I miss a dose?

Because Mapap is prescribed as required, you might not be on a regular dosing schedule. If you're taking the medication frequently, you should take the dose you missed as soon as you can remember. If the next dosage is approaching, avoid missing any doses. Don't use any extra medication to make up for the missed dose.

What happens if I overdose?

Get medical attention immediately or contact the poison help line at 1-800-222-1222. A high dose of acetaminophen could be fatal. The initial signs of a Mapap overdose are appetite loss and nausea, as well as stomach pain, vomiting, sweating, and weakness or confusion. Other symptoms could include pain in your abdomen, dark urine, a yellowing of your skin, or the whites of your eyes.

What should be avoided?

Consult a physician or pharmacist before taking any other cold or allergy medication, sleep medicine, or blood thinner (warfarin, coumadin, or Jantoven). Mapap (sometimes known as APAP) is found in a number of combination medicines. Utilizing certain medications together could cause you to take too much of this drug, which could result in an non fatal overdose. Check the label to find out if a medication has this medicine, or APAP. Beware of drinking alcohol. It can increase the chance of sustaining liver damage while taking Mapap.

Interaction with other drugs

Other medications may interact with Mapap, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about any other medicines you take.