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Generic Name: Nitrofurantoin [NYE-troe-fue-RAN-toin].
Names of Brands: Macrobid, Macrodantin.
Class of Drugs: Urinary anti-infectives.

What is Macrodantin?

Macrodantin is an antibiotic that helps treat infections of the urinary tract caused by bacteria. Macrodantin is also used for reasons not mentioned in this medication guide.

Side effects of Macrodantin

Seek medical attention immediately when you are experiencing symptoms that indicate an allergic reaction (hives, breathing problems, and swelling in your throat or face) or a severe reaction to your skin (fever, sore throat, eye burning, irritation, purple or red skin rash that blisters as well as peels).

Macrodantin could cause serious adverse side effects. Contact your doctor right once, If you are suffering from:

  • Intense stomach pains; diarrhea that is bloody or watery (even if it's months after the most recent dose).
  • Vision issues.
  • Chills, fever, cough, chest pain, difficulty breathing.
  • Tingling, numbness, and burning sensations in your feet or hands.
  • Eye pain that is severe.
  • Pale skin, weakness.
  • Joint discomfort or swelling, glands that are swollen, fever, and muscle aches.
  • Redness, pain, or swelling in your jaw.
  • An increase in pressure within the skull, causing severe headaches, ringing of your ears, dizziness, nausea, vision problems, eye pain.
  • Symptoms of pancreas or liver problems: upper stomach pain (that can be aggravated by back pain) nausea or vomiting, dark urine, eyes that are yellow, or eyes.

Some adverse effects are more common among the elderly.

Common adverse effects of macrodantin could be:

  • Headache, dizziness, drowsiness, weakness.
  • Gas and gastric acid, vomiting, and loss of appetite.
  • Nausea, vomiting.
  • Joint or muscle pains.
  • Itching, itching.
  • Temporary loss of hair.

This isn't a complete list of all the side effects. Other side effects could occur. Contact your doctor to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Do not use Macrodantin in the case of severe kidney disease, urinary issues, or any background of jaundice or liver issues caused by this medication.

Before you take this drug

Macrodantin should not be taken if you have an allergy to the drug or are suffering from:

  • Serious kidney diseases.
  • Urination issues (little, no, or no).
  • An underlying history of jaundice or liver problems triggered by the use of Macrodantin.

Don't take macrodantin in the last week of pregnancy (from 38 weeks to the time of delivery).

Speak to your doctor if you have ever suffered from:

  • kidney disease.
  • Anemia.
  • Diabetes.
  • An imbalance in electrolytes, an electrolyte imbalance, or a vitamin B deficiency.
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency.
  • Any debilitating condition of any kind.

You shouldn't feed a baby younger than one month when you take Macrodantin. Macrodantin shouldn't be given to children less than one month old.

How to take Macrodantin?

Follow the instructions on the prescription label and read the medication guide or instructions sheets. Make sure you use the medication precisely as directed.Take Macrodantin along with your food, even if you take it at night.

shake up the oral suspension (liquid) prior to determining a dose. Utilize the dosing syringe that comes with it or a dosage-measuring device (not the kitchen spoon). You might need to continue taking Macrodantin for up to 7 days following lab tests that indicate there is evidence to suggest that the infection is gone. Follow your doctor's prescriptions. Take Macrodantin for the prescribed duration of time, regardless of whether your symptoms improve immediately. Inadequate doses could increase your chance of contracting an infection resistant to treatment. Macrodantin cannot help treat the symptoms of a viral illness like influenza or the typical cold.

This medication can alter the results of certain tests. Be sure to inform any doctor treating patients that you're using Macrodantin. If you take this medication over a long period of time, you could require regular medical examinations. Place the container in a cool, dry place free of heat, moisture, and light. Avoid freezing the liquid medicine and ensure that the bottle is shut when not in use. Dispose of any macrodantin liquid that has not been used for 30 days.

What happens if I miss a dose?

Do not take the medicine for as long as you are able, but avoid your missed dose if it's nearing the time to take the next dose. Avoid taking two doses at a time.

WHt happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222. Overdoses can cause vomiting.

What should be avoided?

The use of antibiotics can trigger diarrhea, which could be a sign of a new infection. If you are experiencing diarrhea that is bloody or watery and you are unsure of the cause, consult your physician before applying anti-diarrhea medications. Do not take an antacid that is made up of magnesium trisilicate. This can make it more difficult for your body to absorb macrodantin.

Interaction with other drugs

Other drugs can also influence Macrodantin, such as prescription and non-prescription medicines, vitamins, and herbal products. Inform your doctor about your current medications as well as any medications you are about to start or stop taking.



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