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Lymphocyte immune globulin, anti-thymocyte (equine)

Generic names: Atgam (equine), Atgam (anti-thymocyte).
Brands: Atgam
Intravenous Solution (50 mg/ml)
Drug class: selective immunosuppressant

What is Lymphocyte immune globulin, anti-thymocyte (equine)?

Immunosuppressants lower your immune system. Your immune system is in charge of fighting infections.The immune system may also "reject" or fight a transplanted liver or kidney. The immune system views the new organs as invaders.The use of lymphocyte immune globulin to treat or prevent rejection of organs after a renal transplant is common. The lymphocyte immune globulin can also be used to treat aplastic anaemia, a condition where your bone marrow doesn't produce enough new cells.This medication guide does not list all possible uses of lymphocyte immune globulin.

Side effects of Lymphocyte immune globulin, anti-thymocyte (equine)

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, chest pain, pain in your back, swelling of the face, lips, or throat.

If you:

  • Rapid heartbeat trouble breathing
  • Feeling lightheaded as though they could pass out.
  • If you notice any of the following: easy bruising; unusual bleeding (nose or mouth; vagina or rectum); purple or red spots under your skin; or coffee-ground-like vomit or blood.
  • Seizure (convulsions);
  • Low white blood cells: fever; swollen or swollen skin glands; rash and itching; muscle or joint pain.

Side effects of anti-thymocyte lymphocyte immune globulin may include:

  • Other symptoms of infection include fever, chills, or night sweats.
  • Blisters or ulcers on your lips, red or swollen gingivae, difficulty swallowing
  • Nausea, vomiting, diarrhoea;
  • Pain where the medication was injected
  • Red or itchy skin
  • Abnormal liver or kidney function tests
  • Dizziness, headache, confusion,
  • You may experience swelling, redness, irritation, or tenderness of the veins in your arms or legs.

There may be other side effects. For medical advice on side effects, call your doctor. Reaching out to the FDA with any adverse side-effect reports can be done at 1-800-FDA-1088.

Similar/related drugs

Furosemide, Lasix, Azthioprine, Imuran, Promacta, Eltrombopag, and Thymoglobulin

Warnings

This medicine will be administered in a hospital setting or clinic to treat any side effects. Inform your healthcare providers of all medical conditions, allergies, and medicines that you are taking.

Before you take this drug

If you have an allergy to lymphocyte immune serum, it is best not to receive it.

Tell your doctor about any of the following to ensure that lymphocyte immune serum is safe for you:

  • Liver or kidney disease
  • If you received a vaccination in the last 6 months,

Unknown is whether or not lymphocyte immune serum will harm an unborn child. If you plan to get pregnant or are already pregnant, tell your doctor.There is no way to know if lymphocyte immunoglobulin can pass into breast milk or if it would harm a baby who was nursing. This medicine should not be taken while breastfeeding.Lymphocyte Immune Globulin is made from certain blood products of horses and can contain viruses and infectious agents. The blood components are treated and tested to reduce the possibility of them containing infectious agents. However, there is still some chance that they could spread disease. Speak to your doctor about any risks or benefits associated with using this medication.

How to take Lymphocyte immune globulin, anti-thymocyte (equine)?

Your doctor may conduct a skin test before you receive lymphocyte immunoglobulin to ensure that you are not allergic.The lymphocyte immune globulin (LIG) is injected through an IV into a vein. This injection will be given by a healthcare provider.Sometimes, lymphocyte immune globulin (LIG) is given daily. Other times, it's given every two days. The injection of the medicine can take up to 4 hours.While you receive lymphocyte immunoglobulin, other medications may be prescribed to suppress your immune response. You should read all the information provided, including medication guides and instructions. If you have questions, ask your doctor or pharmacist.

You may need to have frequent blood tests while using lymphocyte immunoglobulin.

What happens if I miss the dose?

You are unlikely to miss a dose of lymphocyte immune serum because you will be receiving it in a clinic setting.

What happens if I overdose?

Overdoses are unlikely because the anti-thymocyte lymphocyte immune serum is administered by a health care professional in a medical environment.

What should be avoided?

You should not receive any "live" vaccines for at least six months following your last dose. During this period, the vaccine may not be as effective, and you may not be fully protected from disease. Live vaccines are available for measles (mumps), rubella (MMR), yellow fever, typhoid (rotavirus), varicella, chickenpox, zoster, and influenza (nasal flu).

Interaction with other drug

Other drugs, such as herbal products, vitamins, and prescription medicines, may interact with the lymphocyte immune globulin. Inform your healthcare providers of all the medicines you are taking and those you plan to take.