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Name of the generic: lurasidone
Name of the brand: Latuda
Dosage format: oral tablet (120 mg, 20 mg, 40 mg, 60 mg, 80 mg)
Drug class: atypical antipsychotics

What is Lurasidone?

Lurasidone is an antipsychotic medication utilized to treat schizophrenia in teenagers and adults who are 13 or older.

Lurasidone can also be utilized to treat depression caused by bipolar disorder (manic depression) in children and adults that are at least 10 years old.Lurasidone is also employed for other purposes that are not covered in this guideline.

Side effects of Lurasidone

Contact a medical professional immediately in the event that you exhibit symptoms that indicate an allergy, such as asthma, hives, or swelling of your lips, face, or tongue.

If you notice any new or increased symptoms, tell your physician, for example, changes in your mood or behavior, anxiety, panic attacks, or trouble sleeping, or if you are feeling uncontrollably angry, irritable, and aggressive, active, restless (mentally and physically), or more depressed, or if you are contemplating suicide or harming yourself.

Long-term use or high doses of lurasidone may cause serious movement disorders that may not be reversible. The longer you take the drug, the more likely you are to suffer from this disorder, particularly if you're a female or an older person.

Lurasidone may cause serious side effects. Contact your physician immediately in the event of:

  • Any new or unique muscle movements that you can't be in control of;
  • An euphoric feeling, similar to passing out;
  • A seizure (convulsions);
  • (in females) irregular menstrual cycles (in women) irregular menstrual periods, vaginal or breast change, discharge from the nipple
  • (in males) the breasts are swelling (in males), impermanence;
  • Trouble swallowing
  • Manic episodes: racing thoughts, higher energy, decreased requirement for sleep, risk-taking behaviors, talking or being angry;
  • Low white blood cell count Low white blood cell counts low white blood cell counts—chills, fever, lips sores, scabs, the sore throat, cough, breathing difficulties;
  • High blood sugar—increased thirst, more frequent consumption of food, urination, dry mouth, or breath odor that smells like fruit
  • Nervous system reactions that are severe, very rigid (rigid) muscles, and a high fever sweating as well as confusion, quick or irregular heartbeats, and a feeling that you could faint.

Common negative effects of lurasidone include:

  • Drowsiness;
  • Weight gain
  • Muscle stiffness, tremors, or slow muscle movement
  • Getting restless or finding it difficult to remain still;
  • Nausea, vomiting;
  • A runny nose;
  • Sleep problems (insomnia).

This isn't a complete list of possible side effects, and other effects may also be present. Contact your doctor to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Lurasidone is not a prescription drug for older adults suffering from dementia-related psychosis.

There are people who think about suicide when taking the drug lurasidone. Be vigilant for any changes to your mental state or symptoms. Inform your doctor if you notice any changes or worsening symptoms.

Inform your doctor about all the medicines you currently take as well as any new medications you decide to start or stop taking. Numerous drugs can interact, and certain drugs shouldn't be taken together.

Before you Take this Drug

Lurasidone is not a good choice when you have an allergy to it.

A variety of drugs interact and create dangerous side effects. Certain medications are not recommended to be taken with the drug lurasidone. Your doctor could alter the treatment plan in the event that you are using:

  • Antifungal medicine such as ketoconazole or voriconazole;
  • An antibiotic like clarithromycin or rifampin;
  • An antiviral medication such as ritonavir;
  • St. John's wort
  • Seizure medications like carbamazepine and phenytoin.

Lurasidone can raise the chance of dying in elderly patients suffering from psychosis-causing dementia. It's not approved for this use.

Inform your doctor if you have ever suffered from:

  • Heart disease or stroke;
  • Blood pressure (or lower blood pressure;
  • The highest cholesterol or triglycerides (a type of fat that is found in the blood);
  • Diabetic and high blood sugar (in you or in your family);
  • A seizure;
  • Kidney or liver disease
  • Low white blood cell (WBC) count;
  • Abnormal tests for hormone function (thyroid and pituitary glands);
  • Breast cancer
  • Suicidal ideas or actions.

There are people who think about suicide when taking Lurasidone. Your doctor should examine your progress every few checkups. Family members or other caregivers should be on the lookout for changes in your symptoms or mood.

Antipsychotic medication taken during the last three months of pregnancy can result in breathing difficulties, feeding issues, or withdrawal symptoms in the infant. If you get pregnant, tell your doctor right away. Don't stop using lurasidone unless on the advice of your physician.

If you're expecting, then your name might be included on an OB-GYN registry to track any effects of the drug lurasidone on the child.

It might not be suitable to breastfeed a child while taking the drug lurasidone. Consult your physician about any possible risks.

Lurasidone isn't licensed to treat schizophrenia in people younger than thirteen years of age. Lurasidone has not been recommended to treat depression in children younger than 10 years old.

How to Take Lurasidone?

Follow all instructions on your prescription label and review all medication guides and instruction sheets. Follow the medication exactly as prescribed.

Lurasidone is best taken with food (at a minimum of 350 calories).

It is possible that you will need frequent blood tests.

It could take several weeks before you notice an improvement in your symptoms. Use the medication exactly according to the directions. Contact your physician if your symptoms don't improve or if they become worse when you take the drug lurasidone.

You shouldn't stop using Lurasidone in a hurry. The sudden stop could cause additional problems.

It is much easier to get hyper-hydrated and dangerously dehydrated when you're taking Lurasidone. Get lots of fluids, particularly in the heat and during exercises. It is also possible that you are more sensitive to extreme temperatures (hot and cold). cool).

Keep at room temperature, away from heat and moisture.

What Happens if I Miss the Dose?

You should take the medication as quickly as you are able, but avoid any missed doses if you are nearing the time to take the next dose. Don't take two doses at once.

Refill your prescription prior to the time that you are out of medication completely.

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Do not drink alcohol. Dangerous side effects may be experienced.

Avoid operating machinery or driving until you understand the effects of lurasidone on your body. Be careful not to get up too quickly from a seated or lying posture, as you could experience dizziness. Drowsiness or dizziness could cause injuries, falls, or serious injuries.

Grapefruits and wine can be in contact with lurasidone, which can cause undesirable reactions. Do not consume grapefruit juice when taking Lurasidone.

Interaction with Other Drugs

Utilizing lurasidone along with other medications that slow your breathing may result in dangerous negative side effects or even deaths. Ask your doctor prior to taking opioids, a sleeping pill, a muscle relaxer, or medication for anxiety or seizures.

Inform your doctor about your current medications. Numerous drugs can interact with lurasidone, particularly:

  • Depression or psychotic episodes
  • Sleep problems (insomnia);
  • High pressure in the blood or a heart rhythm disorder
  • Inflammation or swelling;
  • Seizures;
  • Parkinson's disease.

This isn't a complete list, and other drugs could influence Lurasidone. This includes prescription as well as over-the-counter drugs, vitamins, and herbal products. There are many possible interactions between drugs that are included here.



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