What is Lodine? Uses, effects, side effects & warnings

What is Lodine?

Lodine is an NSAID (nonsteroidal anti-inflammatory drug). It reduces hormones that cause inflammation and pain within the body.Lodine can be used to treat mild-to-moderate pain.This medication guide does not list all possible uses for Lodine.

Warnings

If you are suffering from heart disease or have used the drug for a long time, you may be at greater risk of a fatal heart attack. This medicine should not be taken before or immediately after a heart bypass (coronary arterial bypass graft, or CABG).Lodine can also cause fatal stomach or intestinal bleeding. These conditions may occur suddenly, especially among older adults.If you experience symptoms of stomach or intestinal bleeding, call your doctor immediately. You may have black, bloody, or tarry stool, or you might cough up blood or vomit, which looks like coffee ground.Ask your pharmacist or doctor before using any other cold, allergy, or pain medications available over the counter. Aspirin and other drugs similar to etodolac, such as ibuprofen or ketoprofen (or naproxen), are often found in over-the-counter medicines. You may accidentally overdose on this medication if you combine certain products. Check the label to see if any other medication you use contains aspirin or ibuprofen. While taking this medication, do not drink any alcohol. Alcohol can increase your risk of bleeding in the stomach caused by etodolac. Avoid sunlamps and tanning beds. Sunburn can occur if you take this medicine.

Before you take this drug

Lodine may increase your risk of a fatal heart attack or stroke, even if there are no risk factors. This medicine should not be used before or after heart bypass (coronary arterial bypass graft, or CABG).Lodine can also cause fatal stomach or intestinal bleeding. You may not be aware of these conditions if you use this medication, particularly if you are older.Lodine should not be used if you're allergic to etodolac or have had a severe allergic reaction or asthma after taking aspirin.

Tell your doctor about any of the following to ensure that Lodine will be sae for you:

Heart disease: high blood sugar, elevated cholesterol, or diabetes;
A heart attack, stroke, or blood clot
Stomach ulcers or bleeding
Asthma;
Fluid retention;
Liver or kidney disease
If you are taking aspirin for heart attacks or stroke prevention,

Do not take Lodine if you are pregnant unless you have been told to by your doctor. NSAIDs can cause kidney or heart problems for the unborn child and other complications during pregnancy.

Lodine should not be used by anyone under the age of 18.

Similar/related drugs

Simponi, olumiant, aspirin, acetaminophen, prednisone, ibuprofen, and tramadol

How to take Lodine?

Lodine should be taken exactly as prescribed by a doctor. Read all the instructions on the prescription label. Use the lowest effective dose to treat your condition.The extended-release tablet should not be chewed, crushed or broken.Your symptoms may not improve for up to two weeks. Continue to take the medication according to instructions, and inform your doctor if you do not see improvement in your symptoms.You may need to undergo frequent medical tests if you are using Lodine for a long time.Lodine can interfere with certain medical tests. Lodine can affect the results of certain medical tests.Keep away from moisture and heat at room temperature. When not in use, keep the bottle tightly shut.

Details on dosage

Adult dose of lodine:

Immediate release:
Initial dose: 300mg orally, 2 to 3 times a week, or 400mg to 500mg orally, twice a week.
Maintenance dose: 600 mg/day is sufficient for long-term usage.
Maximum dose: 1000 mg/day
Extended Release: 400mg to 1000mg orally, once daily
Comments:
The therapeutic response is usually observed within 2 weeks of the start of treatment but can occur as early as 1 week. After a satisfactory response has been achieved, doses may need to be adjusted.
Uses: acute and long-term treatment of the signs and symptoms associated with osteoarthritis or rheumatoid arthritis.

Adult dose of lodine to treat rheumatoid arthritis:

Immediate release:
Initial dose: 300mg orally, 2 to 3 times a week, or 400mg to 500mg orally, twice a week.
Maintenance dose: 600 mg/day is sufficient for long-term usage.
Maximum dose: 1000 mg/day
Extended Release: 400mg to 1000mg orally, once daily
Comments:
The therapeutic response can be observed within one week but is usually seen after two weeks. After a satisfactory response has been achieved, the dose should be adjusted.
Uses: acute and long-term treatment of the signs and symptoms associated with osteoarthritis or rheumatoid arthritis.

Adult dose of Lodine:

Take 200 to 400 mg every 6 to 8 hours.
Maximum dose: 1000 mg/day
Use: To manage acute pain

The usual paediatric dose of lodine in juvenile rheumatoid arthritis:

Extended Release
From 6 to 16 years:
20–30 kg: 400mg orally, once per day
31 to 45 kg: 600 mg once daily orally
40–60 kg: oral 480 mg once daily
More than 60 kg: oral, 1000 mg once daily
17 to 18 years: 400 mg to 1,000 mg orally, once daily
Use: To relieve the symptoms and signs of juvenile rheumatoid arthritis.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of a medicine at the same time.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.Overdose symptoms can include vomiting, nausea, abdominal pain or bleeding.

What should be avoided?

They may contain ingredients similar to etodolac (such as a href="https://www.drugs.com/ibuprofen.html">ibuprofen/a>, a href="https://www.drugs.com/mtm/ketoprofen.html">ketoprofen/a>, or naproxen). These medicines may contain similar ingredients to etodolac, such as ibuprofen or ketoprofen.Aspirin should only be taken if your doctor recommends it.Avoid alcohol. The risk of bleeding in the stomach can be increased by alcohol.Ask your doctor about antacids, and only use the ones that your doctor has prescribed. Some antiacids may make etodolac harder to absorb.

Side effects of Lodine

If you experience any of the following symptoms: hives, runny nose, difficulty breathing, swelling around your mouth or face, or severe skin reactions (fever or sore throat, burning in your eyes, skin pain, or blistering), seek emergency medical attention.

Seek immediate medical care if you notice any of the symptoms.

If you experience any of the following symptoms, stop using Lodine immediately and contact your doctor:

Changes in your vision
Any skin rash;
Shortness of breath even with mild exercise
Swelling or rapid weight gain
Signs of stomach bleeding—bloody or tarry stool, coughing blood, or vomit that looks like coffee grounds
Liver problem: upper stomach pain, nausea (yellowing or discoloration of the skin and eyes), fatigue, dark urine
Kidney disease: little or no urine, swelling of your ankles or feet, fatigue, or
Anaemia (low red blood cells), pale skin, unusual fatigue, feeling lightheaded, cold fingers and fee

Lodine is commonly used to treat:

Nausea, vomiting, stomach pain, indigestion;
Diarrhoea, constipation, gas;
Dizziness; headache;
Rash;
Ringing in the ears

There may be other side effects. Call your doctor for medical advice about side effects. To report adverse effects, you can contact the FDA at 1-800-FDA-1088.