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Generic name: linagliptin [LIN-a-GLIP-tin]
The brand name is Tradjenta.
Dosage format: oral tablet (5 mg)
Drug class: dipeptidyl peptidase 4 inhibitors

What is Linagliptin?

Linagliptin can be used in conjunction with exercise and diet to help improve blood sugar control in adults suffering from Type 2. diabetic mellitus. Linagliptin is not a remedy for type 1 diabetes.

Linagliptin can also be used for reasons not mentioned in this guideline.

Side effects of Linagliptin

Take immediate medical care when you are experiencing symptoms that indicate an allergy (hives, rashes, and peeling; difficult breathing; swelling on your throat or face) or an extreme skin reaction (fever or sore throat; burnt eyes; irritation; the skin is red or purple with peeling and blisters).

Stop taking linagliptin and call your doctor immediately if you are suffering from the signs and symptoms that suggest pancreatitis, which causes intense stomach pain that extends to your back as well as vomiting.

Linagliptin may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • Persistent or severe joint pain that is persistent or constant;
  • An extreme autoimmune reaction characterized by itching and blisters, a breakdown of the skin's outer layer,
  • Signs and symptoms of heart failure signs of heart failure breathing problems (even when lying down). swelling of your feet or legs and rapid weight gain.

Common adverse effects of linagliptin could be:

  • Stuffy or runny throat or nose;
  • Cough
  • Diarrhea.

It's not a comprehensive description of the various negative consequences. There are other possibilities for this to happen. Ask your physician for advice on the effects of medicine. If you experience any adverse negative effects to the FDA by calling 1-800-FDA-1088.


Linagliptin could cause severe, potentially life-threatening pancreatitis (inflammation of the pancreas). Do not take linagliptin, and contact your doctor immediately in the event of discomfort in your stomach, which may be spreading to your back, with or without vomiting.

Contact your physician for any signs of heart problems, including weight gain, swelling, or breathing problems (even when lying on your back).

Before you Take this Drug

There is no reason to apply linagliptin if

  • You've had an extreme allergy to the molecule linagliptin (breathing issues, swelling, or an extreme skin rash)
  • You have diabetes ketoacidosis (call your doctor to seek treatment).

Speak to your doctor if you have ever suffered from:

  • Heart-related problems;
  • Kidney disease;
  • Pancreatitis;
  • Triglycerides with high levels (a kind of fat found in the blood);
  • Gallstones
  • Alcoholism.

Inform your doctor if you are nursing or pregnant.

Follow the directions of your doctor regarding the use of this medication when you are pregnant or are planning to become pregnant. Controlling diabetes is essential during pregnancy. High blood sugar levels could cause issues for pregnant mothers as well as their babies.

This medicine is not authorized for use by anyone younger than 18 years old.

How to Take Linagliptin?

Follow the directions on the prescription label and study all medication guides or instruction sheets. The doctor might change the dosage. Follow the medication precisely as directed.

It is possible to take linagliptin either in combination with food or not.

It is possible to suffer from insufficient levels of blood sugar (hypoglycemia) and experience extreme hunger, dizziness, anger, and anxiety. You may also feel confused or even shaky. To manage hypoglycemia, consume or drink rapid-acting sources of sugar (fruit juice, crackers, hard candy, crackers with raisins, and other non-diet drinks).

Your physician may recommend a glucagon injection kit if you suffer from severe hypoglycemia. It is important that your family or friends are aware of the procedure for giving you the injection in the event of an emergency.

The levels of blood sugar are affected when there is illness, stress, surgery, drinking alcohol, exercise, or avoiding meals. Talk to your doctor before altering your dosage of medication schedule.

Linagliptin is just one component of a treatment plan that may comprise exercise, diet, controlling weight, blood sugar tests, and other medical treatments. Follow the instructions of your physician precisely.

Place it in a cool, dry place far from heat and moisture.

Details on Dosage

Usual Adult Dose for Diabetes Type 2:

The recommended dose is 5 mg taken orally, once a day.
Comments that are used in conjunction with insulin or an insulin secretagogue suggest that a lower dose of insulin secretagogue or insulin could be required to lower the chance of developing hypoglycemia.
Make use of: add-ons to exercise and diet to increase glycemic control for adults suffering from type 2 diabetes mellitus

What Happens If I Miss a Dose?

Do not take the medicine for as long as you can. However, avoid your missed dose if you are close to the time of the next dose. Don't take two doses at once.

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Follow your doctor's advice regarding any restrictions on your food, drink, or activities.

Interaction with Other Drugs

Other medications may enhance or reduce the effect of linagliptin on lowering blood sugar levels. Inform your doctor about any other medications you take, including:

  • Rifampin (to combat tuberculosis) as well as
  • Insulin or other diabetes-related medications that are taken orally.

This list is not exhaustive. Other medications can affect the effects of linagliptin. They include over-the-counter and prescription supplements, vitamins, as well as natural products. Some interactions with drugs are not listed here. are included here.