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Lamivudine Tenofovir

Generic name: lamivudine and tenofovir [la-MIV-ue-deen-and-ten-OF-oh-vir]
Brand names:
Cimduo, Temixys
Form of dosage: oral tablet (300–300 mg).
Drug class: antiviral combinations

What is Lamivudine Tenofovir?

Tenofovir and Lamivudine are antiviral medications that stop the human immunodeficiency virus (HIV) from multiplying within your body.Combination medicine that treats HIV (the virus that can cause acquired immune deficiency syndrome) and AIDS. Lamivudine is not a cure or treatment for HIV/AIDS.Lamivudine is prescribed to adults and children weighing at least 77 lbs.This medication guide does not list all possible uses of Lamivudine or Tenofovir.

Side effects of Lamivudine Tenofovir

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing and/or swelling of lips, face, tongue or throat. Seek medical assistance immediately!

There are serious side effects associated with Lamivudine or Tenofovir. If you experience:

  • New or worsening pain in the bones
  • Muscle weakness
  • You may experience pain in your hands, arms, legs, or feet.
  • Swelling around your midsection;
  • If you have kidney problems, it could be that your urine is not as frequent or that you are experiencing swelling of the feet or ankles or feeling tired.
  • Signs of liver or pancreas issues include loss of appetite (which may extend to the back), upper stomach pain, nausea, and vomiting. Other symptoms are dark urine, clay-coloured stools, and jaundice.

The immune system is affected by Lamivudine/Tenofovir, which can cause side effects even weeks or months after taking this medication. You should tell your doctor if:

  • Signs of an infection: fever, sweats at night, swollen lymph glands, colds, sores, coughing, wheezing, and diarrhoea.
  • If you have difficulty speaking or swallowing, have problems with balance, eye movements, or weakness, or feel prickly, then it could be a sign of a problem.
  • Impotence, menstrual changes, swelling of the neck or throat (enlarged thyroid)

Some of the common side effects associated with lamivudine or tenofovir include:

  • Headache;
  • Pain;
  • Diarrhoea;
  • Rash;
  • Is a depressive
  • Changes in the shape or location (especially of your arms, legs, and breasts), as well as changes in your body fat.

There may be other side effects. Call your physician if experiencing side effects; alternatively, the FDA can be reached at 1-800-FDA-1088 if reporting concerns about them.

Similar/related drugs

Biktarvy, Descovy, Truvada Tenofovir Atripla Complera and Stribild are available as antiretrovirals to treat HIV infection.

Warnings

Lamivudine can have serious side effects. If you experience symptoms like upper stomach pains, loss of appetite, dark urine, yellowing skin or eyes, muscle pain, or bone pain, call your doctor immediately.You could develop lactic acidosis. This is a dangerous buildup of lactic acid in your blood. If you experience unusual pain in your muscles, difficulty breathing, stomach pains, dizziness, or feel cold or very tired, call your doctor.After stopping lamivudine or tenofovir, if you have ever had hepatitis B, it could become active again or worsen. You may require frequent liver function testing for several months.

Before you take this drug

This medicine should not be used if you have an allergy to lamivudine and tenofovir.

Inform your physician of any of the following issues:

  • Liver disease includes cirrhosis and hepatitis C or B (especially if also using ribavirin or interferon beta);
  • Kidney disease (or dialysis if you have it);
  • A pancreas disorder;
  • Bone problems include osteoporosis and a broken bone.

You can develop lactic acidosis. This is a dangerous accumulation of lactic acids in your blood. It may be more common if there are other medical conditions or you've been taking HIV medication for some time. Consult your doctor to determine your risk.Use your medication properly to control infections. HIV can be transmitted to your child if you do not control the virus during pregnancy. You may have your name listed in a registry that tracks the effects of antiviral medicines on the baby.Breastfeeding is not recommended for women with HIV/AIDS. Even if the baby was born HIV-free, the virus can be transmitted to the infant through your breast milk.

How to take Lamivudine or Tenofovir?

You will be tested by your doctor to ensure that you are not suffering from any conditions that would make it unsafe for you to use lamivudine or tenofovir.Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label.Take lamivudine or tenofovir either with food or without.You may need to undergo frequent medical tests. You may need to have your kidney and liver functions checked.The doses of Lamivudine or Tenofovir are determined by the weight of children. If your child gains or loses weight, the dose requirements may change.Read all the instructions and medication guides that you receive. Do not alter your dosage or schedule without consulting your doctor. Each person living with HIV should be under the care and supervision of a physician.Store the container in its original container, at room temperature, and away from moisture.You may need to have frequent liver function tests while taking this medicine and for several months after your last dose. You may require frequent liver function testing while taking this medication and for a few months afterward.

Details on dosage

Adult dose for HIV infection:Take 1 tablet once daily, orally.
Use: As a combination with other antiretroviral drugs for HIV-1 infection.The usual paediatric dose for HIV infection is:If you weigh at least 35 kg, take 1 tablet once daily.
Use: As a combination with other antiretroviral drugs for HIV-1 infection.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.Refill your prescription before you run out.

What happens if I overdose?

Call 1-800-222-1222 immediately if you suspect poisoning and seek immediate medical care.

What should be avoided?

Avoid taking any other medicines that contain the ingredient sorbitol. This is often used to sweeten liquid medications. If you're not sure whether a medication contains this ingredient, ask your pharmacist.Lamivudine or tenofovir won't stop your illness from spreading. Share razors and toothbrushes. Do not engage in unprotected sexual activity. Speak to your doctor about the best ways to prevent HIV from being transmitted during sex. Even healthy people should never share syringes for drugs or medicines.

Interaction with other drug

If you use Advil, Motrin, or Aleve, it can cause kidney damage.

Inform your doctor of all other medications you are taking, including antivirals for HIV or Hepatitis C.Lamivudine or tenofovir may be affected by other drugs, such as vitamins and herbal remedies. Informing your physician of all medications you are currently taking and any that have changed or begun use is very important for their safe administration and use.