Kazano

What is Kazano?

Kazano is a mixture made up of alogliptin and metformin. Alogliptin and metformin are oral diabetes drugs that aid in controlling blood sugar levels. Metformin is a drug that reduces sugar production in the liver. It also reduces the absorption of glucose through the digestive tract. Alogliptin is a drug that regulates the levels of insulin that your body produces following a meal. Kazano is an exercise and diet program to increase blood sugar control in people suffering from type 2 diabetes. Kazano is not used to treat type 1 diabetes.

Warnings

You shouldn't take Kazano if you suffer from severe kidney disease or diabetic ketoacidosis (call your physician to seek treatment). There is a chance that you will be diagnosed with an illness called lactic acidosis. This is an extremely dangerous accumulation of lactic acid in your blood. Contact your physician or seek urgent medical attention in the event of unusual muscle pain, breathing difficulties, stomach pain, dizziness, feeling cold, exhausted, or weak. Alogliptin may cause pancreatitis. Stop taking Kazano and consult your physician immediately if you notice intense discomfort in your stomach that is spreading to your lower back, nausea and vomiting, and a loss of appetite.

Before you take this drug

You shouldn't make use of Kazano in the event that you are allergic to metformin or alogliptin or if you suffer from an extreme kidney condition or diabetes ketoacidosis (call your physician to seek treatment).

Speak to your doctor if you have ever suffered from:

• kidney disease.
• Heart disease.
• The liver condition.
• Pancreatitis.
• Gallstones.
• Alcoholism.

It is possible to be diagnosed with an illness called lactic acidosis. This is an extremely dangerous accumulation of the acid lactate inside your blood. It is more likely in the event of any other medical condition, a serious infection, chronic alcoholism, or if you're 65 or older. Consult your physician about the risks. If you require any kind of x-ray or CT scan that uses an injection of dye in your blood vessels, then you might need to temporarily stop taking Kazano. Make sure that your healthcare providers know prior to taking this drug. Follow the instructions of your physician about the use of Kazano when you're expecting or are planning to become pregnant. Controlling diabetes is essential during pregnancy, and high blood sugar could cause problems for both the mother and the infant. It is not always safe to breastfeed when using Kazano. Discuss any risks with your doctor. This medication can stimulate the ovulation process in women who are premenopausal and increase the chance of an unplanned pregnancy. Discuss with your doctor the possibility of having a baby. This medicine is not FDA-approved to be used by anyone less than 18 years of age.

How to take Kazano?

Use Kazano exactly as directed by your physician. Follow all instructions on your prescription label and review all medication guides and instruction sheets. Have Kazano at meals. It is possible that you have lower levels of blood sugar (hypoglycemia) and feel extremely hungry, dizzy, and confused. You may also feel irritable, angry, and shaky. To treat hypoglycemia quickly, consume or drink a rapid-acting sugar source (fruit juice crackers, hard candy raisins, or other non-diet drinks).

The doctor might prescribe an injection kit of glucagon for those suffering from severe hypoglycemia. Make sure that your family or friends are aware of how to administer this injection in the event of an emergency. Be aware of symptoms of excessive levels of blood sugar (hyperglycemia), like more thirst or frequent urination. The levels of blood sugar can change due to stress, illnesses, surgery, drinking alcohol, exercise, or avoiding meals. Talk to your physician before altering your medication or dosage schedule. Kazano is just one part of a full treatment program that may comprise exercise, diet control, regular blood sugar tests, and specialized medical care. Follow your doctor's advice carefully. Your doctor may suggest you take an additional dose of vitamin B12 when you take Kazano. You should only take the amount of vitamin B12 prescribed by your physician. Advised. Maintain the product at room temperature and away from heat and moisture sources.

Details on dosage

Standard Adult Dose of Kazano for Diabetes Type 2:

Make the dose individual according to the current regimen of the patient.
Initial dosage to begin: alogliptin 12.5 mg-metformin, 500 mg, or alogliptin 12.5 mg-metformin, 1000 mg, taken orally at least twice daily.
Dosage for maintenance Modify dose in accordance with efficacy and tolerance.
Maximum dose: alogliptin 25 mg/metformin 2000 mg per day
Comments: If used in conjunction with insulin and insulin secretagogues, such as sulfonylureas, a reduced dosage of insulin or insulin secretagogue might be needed to reduce the chance of developing hypoglycemia.
The dose of metformin is recommended to be gradually adjusted and taken along with food in order to lessen the stomach's adverse effects.
Use: As an addition to exercise and diet, to help improve the control of glycemic levels in people suffering from the condition of type 2 diabetes, when treatment with Kazano is appropriate.

What happens if I miss a dose?

Do the medication (with food) immediately if you are able, but don't take any missed dosage if you are close to the time of the next dose. Don't take two doses at once.

What happens if I overdose?

Get medical attention immediately or contact the poison help line at 1-800-222-1222 for help. It is possible that you have severely low levels of blood sugar (extreme weakness and nausea, tremors or nausea, sweating, confusion, difficulty speaking, rapid heartbeats, or a seizure).

What should be avoided

Do not drink alcohol. It reduces blood sugar levels and can increase the chance of contracting lactic acidosis.

Side effects of Kazano

Seek medical attention immediately when you are experiencing symptoms that indicate an allergic reaction (hives or breathing difficulties and swelling in your throat or face) or an extreme skin reaction (fever and throat soreness, burnt eyes, irritation, red or purple eruptions with peeling and blisters). Take a break from Kazano and contact your doctor immediately if you experience pancreatitis symptoms, which are characterized by intense pain in your stomach that is spreading into your back, nausea and vomiting, weight loss, or rapid heartbeats. Certain people who take metformin suffer from lactic acidosis, which is a fatal condition. Seek medical attention immediately. If you have even slight symptoms such as:

• Unusual muscle pain.
• Feeling cold.
• Trouble breathing.
• Feeling lightheaded, dizzy, exhausted, fatigued, or weak.
• Stomach pain, vomiting.
• A heartbeat that is slow or irregular.

If you are suffering from, see your doctor as soon as possible:

• Persistent or severe pain in your joints.
• Discomfort or burning sensation after you urinate.
• Liver issues nausea, stomach pain, fatigue, and loss of appetite. bloody urine, jaundice (yellowing of the eyes or skin).
• Signs for the heart Symptoms of heart failure include shortness of breath (even in a reclining position), swelling of your feet or legs, and a rapid weight increase.

Common Kazano side effects may include:

• Diarrhea, upset stomach.
• Increased blood pressure (severe headache, blurred vision, pounding on your neck or ear).
• Lower back pain, headache, back pain.
• Symptoms of a cold, like sinus pain, a stuffy nose, and a sore throat.

This isn't a complete list of all the side effects. Other side effects could occur. Contact your doctor for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Numerous drugs can be incompatible with metformin and alogliptin, which can make this medication less effective or increase your chance of developing lactic acidosis. This includes over-the-counter and prescription supplements, vitamins, and products made from herbs. Not all interactions are included on this page. Discuss with your doctor all of your prescriptions, as well as any new or discontinued medications.