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Isovue-250

Generic name: iopamidol [eye-oh-PAM-ih-dol]

Brand names: Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M-200, Isovue-M-300
Nonionic iodinated contrast media

What is the Isovue 250?

Isovue 250 is a radiopaque contrast agent (RAY DEE OOH PAK). This medicine contains iodine, which is a substance capable of absorbing x-rays. The radiopaque contrast agent is used to make it easier to see blood vessels, organs, and non-bony tissue on a CT scan.

Isovue 250 is used to diagnose certain disorders of the heart, brain, and blood vessels, as well as the nervous system. This medication guide does not list all possible uses of Isovue 250.

Side effects of Isovue-250

If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat with burning, pain in the eyes, or skin rash, which is red or purple and blisters or peels), seek emergency medical attention.

If you experience a severe drug reaction, seek medical attention. This can include a skin rash, fever, or flu-like symptoms. Other symptoms may include muscle aches or weakness, unusual bruises, or a yellowing of the skin or eyes.

Isovue 250 may cause serious side effects. If you experience:

  • Are You Feeling Dizzy and Lightheaded? If that describes you, this could be a warning of lightheadedness and could potentially lead to fainting.
  • Weight and fluid gain is occurring rapidly, while there is minimal to no urination.
  • Difficulty breathing
  • Seizure (convulsions);
  • You may experience swelling of the neck or throat.
  • Symptoms of thyroid disease include extreme tiredness, dry skin, stiffness or joint pain, muscle weakness or pain, hoarseness in voice, sensitivity to cold temperatures, and weight gain.
  • Heart attack symptoms: chest pain or pressure, spreading pain to your jaw and shoulders, nausea, or sweating.
  • Signs of a blood clot in the lungs: chest pain, sudden cough, shortness of breath, or coughing up blood
  • Signs of a stroke include sudden numbness and weakness, especially on one side; a severe headache or slurred or shaky speech; or problems with vision or equilibrium.

Isovue 250 may cause side effects such as:

  • Chest pain;
  • Slow heartbeat
  • Hot flashes; burning sensation
  • Flushing (warmth, tingling, or redness);
  • Nausea;
  • Hives

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

Diazepam, valium, simethicone, hyoscyamine, levsin, and iopamidol

Warnings

If you are infected with Isovue 250, it should not be given to you.

Before you take this drug

Inform your physician of any of the following issues:

  • Any type of reaction to a contrast agent.
  • Liver or kidney disease
  • Heart diseases, including congestive cardiac failure.
  • Stroke, blood clots, or coronary arterial disease.
  • Asthma; hay fever; food allergies
  • Epilepsy
  • Sickle-cell anemia
  • Diabetes;
  • An active infection
  • Pheochromocytoma
  • Multiple myeloma; bone cancer
  • A thyroid disorder.

Isovue 250 is not known to harm unborn babies. Inform your doctor if you are pregnant. Inform your doctor if breastfeeding is taking place.

How to take Isovue 250?

Isovue 250 is infused into a vein. This injection will be given by a healthcare provider. While you receive Isovue 250, you may be prescribed medication to help prevent certain side effects. If you experience any pain or swelling when Isovue 250 is injected, tell your carers.

Drink more fluids both before and after the radiologic test. Dehydration can be caused by isovue 250, and this can have dangerous effects on the kidneys. You should follow your doctor's advice on the type and amount of fluids to drink before and following your test. You may need to take extra care with older adults in order to prevent dehydration. You may need to have your kidney function checked after receiving Isovue 250.

Some reactions to Isovue 250 have started 30–60 minutes after the first injection. You may be watched by your carers during this time. You want to be sure that you don't have any side effects or delayed reactions. You may experience interference with medical tests up to 16 weeks after taking this medication. Inform any doctor that treats you about the recent use of this medication.

What happens if I miss the dose?

You will not have a schedule of doses since Isovue 250 is only used during radiologic tests.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

You should not become dehydrated in the first few days following Isovue 250. If you experience any diarrhea or nausea, call your doctor. You should follow your doctor's advice on the type and amount of fluids to drink.

Interaction with other drug

Tell your doctor all of your current medications, including:

  • Diabetes medicine that contains metformin. (Glucophage Glucovance Actoplus Met prandimet Avandamet Janumet Kazano Invokamet Jentadueto Xigduo Synjardy Metaglip and others

This list is incomplete. Isovue 250 may be affected by other drugs, such as prescription and over-the-counter medicines and vitamin and herb products. This list does not include all possible drug interactions.