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What is Inlyta?
Inlyta, a prescription drug, interferes with some cancerous cells' growth.Inlyta can be used to treat advanced renal cancer.
Inlyta can be given when at least one cancer treatment has failed or stopped working.Inlyta may be safe and effective for children, but this is unknown.
Warnings
Inlyta should not be used if you're pregnant. It may harm an unborn child. You should use birth control to avoid pregnancy while taking this medication, whether you're a man or woman. Use of Inlyta by either parent can cause birth defects or miscarriage.
Axitinib increases your risk of bleeding. Call your doctor immediately if you experience severe stomach pain, have bloody or tarry stool, are coughing blood, or are experiencing any unusual or heavy bleeding.
Some people who take this medication have developed fistulas (an abnormal passageway or hole) in the stomach or intestines. If you experience severe stomach pain or feel as if your throat is closing up, call your doctor.Inlyta should be taken every 12 hours. Take it at regular intervals. You should follow your doctor's advice.
Tests on your thyroid, liver, and kidney function are required to ensure that this medication does not have any harmful side effects. You will need to check your blood pressure regularly. Visit your doctor regularly.
Before you take this drug
Inlyta should not be used if you have an allergy to axitinib.
Tell your doctor about any of the following to ensure that Inlyta will be safe for you:
- A perforation is a hole (or tear) in the stomach or intestines.
- A wound that is not healing or has bleeding problems;
- A heart attack or heart failure;
- High blood pressure
- Liver disease
- A thyroid disorder.
Before starting the treatment, you may need a negative pregnancy result.The use of Axitinib by either the mother or father can harm an unborn child.Continue to use birth control at least one week after you have taken your last dose. If you or your partner become pregnant while using Inlyta, tell your doctor immediately.
Both men and women may be affected by this medicine. It is still important to use birth control to avoid pregnancy, as axitinib may harm the unborn child.Do not breastfeed your baby for at least two weeks after you have taken this medication.
How to take Inlyta?
Follow the directions on your prescription label and read all medication guides or instructions sheets. Read all the instructions and directions that come with your prescription. Sometimes your doctor will change the dose.Inlyta can be taken evenly spaced at intervals of 12 hours.
Take this medicine with water. You can take this medicine with or without food.The tablet should not be chewed, crushed or broken.Do not take another Inlyta dose if you vomit soon after taking it. Do not take another dose of Inlyta until you have taken your next scheduled dosage.
You will also need frequent medical tests. It is possible that you will also require frequent medical tests.
Tell your surgeon that you are currently using Inlyta if you need to have surgery. Stop using Inlyta at least 24 hours prior to a scheduled surgery.Keep away from moisture and heat at room temperature.
Details on dosage
Adult dose for renal cell carcinoma:
Initial dose: oral, 5 mg twice daily
Maintaining dose: Increase or decrease the dose according to individual tolerance and safety.
Dose range: between 2 and 10 mg twice daily.
Comment: The doses should be approximately 12 hours apart.
Use: To treat advanced renal cell carcinoma following the failure of one prior systemic treatment.
What happens if I miss the dose?
Do not take the missed dose. Use your next dose as usual. Take only one dose at a time.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Grapefruit can interact with axitinib, causing unwanted side effects. Avoid grapefruit products.
Side effects of Inlyta
If you experience any of the following symptoms of an allergy to Inlyta, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat.
Inlyta can cause a perforation or fistula in the intestines or stomachs of some people. If you experience severe stomach pain or feel as if your intestines are being ripped apart, call your doctor.
Call your doctor immediately if you:
- Chest pain or pressure spreading to the jaw or shoulder;
- Sudden numbness, weakness, or problems with speech or vision;
- Headache; confusion; thinking difficulties; seizures (convulsions);
- A feeling of lightheadedness, as if you could pass out.
- Easy bruising, unusual bleeding, or purple or red patches under the skin
- Heavy bleeding during menstruation
- Any bleeding that won't stop
- Liver problems: nausea, vomiting, upper right stomach pain, loss of appetite, dark urine, and clay-coloured stools; jaundice.
- Heart problem: rapid weight gain and a feeling of shortness of breath.
- Signs of stomach bleeding: bloody or tarry stool, coughing blood, or vomit that looks like coffee grounds
- Signs and symptoms of thyroid problems: sudden weight gain, loss or change; feeling weak, tired, or hot; muscle pains; feeling cold or hot; loss of hair; or a hoarse voice.
Inlyta may cause side effects such as:
- Liver problems
- Stomach pain;
- Muscle and bone pain
- Blood tests that are abnormal
- Mouth sores or swelling in the lining of your mouth, nose, eyes, throat, or intestines;
- Shortness of breath, cough
- Headache;
- Nausea, vomiting, diarrhea, constipation;
- Itching, rash, and skin peeling on the hands or feet
- Feeling tired or weak
- Increased blood pressure
- Weight loss or decreased appetite
- Hoarse voice.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Interaction with other drug
It is sometimes not a good idea to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, causing side effects or making them less effective.
Other drugs, such as vitamins and herbal remedies, may interact with axitinib. Inform your doctor of all the medicines you are taking and those that you stop or start using.