What is Hyoscyamine, methenamine, methylene blue, and sodium biphosphate?
Hyoscyamine has many effects on the body, including the relief of muscle spasms.Methylene blue and methenamine are mild antiseptics that fight bacteria in urine and the bladder.Sodium biphosphate, a naturally occurring substance, is a form of phosphorus.A combination medicine containing methenamine and sodium biphosphate is used to treat bladder inflammation (pain, swelling, or burning) due to a urinary infection. Hyoscyamine, methenamine, methylene, and sodium biphosphate are also used to reduce bladder discomfort when undergoing a medical procedure.This medication guide does not list all possible uses for hyoscyamine, methenamine, methylene blue, and sodium biphosphate.
Side effects of Hyoscyamine, methenamine, methylene blue, and sodium biphosphate
Your urine or stools will likely appear green or blue if you use methylene blue. This is not a harmful side effect and is normal.If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat.
This medicine can cause serious side effects. If you experience:
- Severe dizziness, blurred vision, and a fast heart rate;
- Confusion, agitation, or feeling restless;
- Urination that is painful or difficult
- Shortness of breath
This medication may have more side effects for older adults.
Side effects that may occur from hyoscyamine (methenamine), methylene blue (methylene), and sodium biphosphate include:
- Mild dizziness;
- Dry mouth;
- Nausea, vomiting.
There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA in regards to adverse events is easy - call them on their toll free number 1-800-FDA-1088 today.
Similar/related drugs
Amoxicillin, Doxycycline, Ciprofloxacin, Augmentin, Amoxicillin/clavulanate, and Ceftriaxone
Warnings
Tell your eye doctor if you plan to use hyoscyamine (methenamine), methylene blue, or sodium biphosphate before you go for an eye examination.
Before you take this drug
This medicine should not be used if you have an allergy to methenamine or sodium biphosphate.
Tell your doctor about any of the following to ensure that this medication is safe for you:
- Heart disease
- A heart rhythm disorder.
- Congestive heart failure;
- Coronary heart disease
- A heart valve disorder;
- Glaucoma;
- An enlarged bladder;
- Myasthenia gravis;
- An ulcer or obstruction of the stomach.
- If you have an allergy to belladonna, donnatal, or other products,
This medication is not known to harm a baby in utero. If you plan to get pregnant or are already pregnant, tell your doctor.This medicine may pass into breast milk and harm a nursing infant. You should tell your doctor if a child is breastfed.This medicine is not recommended for children younger than seven years of age.
How to take Hyoscyamine, methenamine, methylene blue, and sodium biphosphate?
Do not take more or less than prescribed, or for longer than necessary.. Take this medication only as prescribed. Do not exceed the recommended dosage or take it for a longer time.Do not crush, chew, or break enteric-coated pills. Swallow them whole. The coating on the pill is designed to protect your stomach. This coating will be damaged if you break the pill.Take this medication with plenty of fluids.Tell your eye doctor if you plan to use hyoscyamine (methenamine), methylene blue, or sodium biphosphate before you go for an eye examination.Store away from heat and moisture at room temperature. When not in use, keep the bottle tightly shut.
Details on dosage
Adult dose for urinary tract infection:
Hyoscyamine/methenamine/m-blue/sodium biphosphate 0.12 mg-81.6 mg-10.8 mg-40.8 mg oral tablet:
Take one tablet four times a day.
What happens if I miss the dose?
As soon as possible, take the missed dose. If your next scheduled dosage is approaching quickly, skip it instead; additional medicine should never be taken to make up for missed ones.
What happens if I overdose?
Dial 1-800-222-1222 immediately in case of poisoning and seek immediate medical assistance.
What should be avoided?
Avoid taking an anti-diarrhea or antacid within one hour of hyoscyamine or methenamine. Anti-diarrhea or antacids can interfere with the absorption of hyoscyamine.Wait at least two hours after you have taken ketoconazole before taking hyoscyamine (methenamine), methylene blue, and sodium biphosphate.
Interaction with other drug
Among the drugs that can interact with sodium biphosphate, methylene blue, hyoscyamine, and methenamine are: This list does not include all possible interactions. Hyoscyamine may also make it more difficult for you to absorb other medications that you take orally. Tell your doctor if you change or stop taking any medications.
- Neostigmine or pyridostigmine;
- You can also use bladder or urinary medications such as darifenacin (fesoterodine), oxybutynin (tolterodine), solifenacin, and fesoterodine.
- Bronchodilators, such as ipratropium and tiotropium.
- A cold or allergy medication that contains antihistamine
- A diuretic, or "water pill".
- Mao inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline and tranylcypromine;
- Treatment for excess stomach acid, stomach ulcers, or motion sickness
- If you have gout, kidney stones, or a low potassium level, then medication may be prescribed to correct the imbalance.
- Medications to treat the symptoms of alzheimer’s disease and parkinson’s disease
- Codeine, hydrocodone hydromorphone, methadone, morphine, oxycodone, propoxyphene, and other narcotic cough or pain medications;
- Sulfa drugs.
The list does not include all drugs that can cause interactions with hyoscyamine. Included are prescription and over-the-counter medicines, vitamins, and herbal products. List all of your medications with your healthcare providers.
