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Hydrocodone and homatropine

Generic name: homatropine and hydrocodone [HOM-a-TROE-peen-and-HYE-dro-KOE-done]
The brand names are: Hycodan, Hydromet, Tussigon, Hydrotropine, Hydromide, and Hydropane.
Forms of dosage: oral syrup (1.5 mg–5 mg/mL) or oral tablet (1.5 mg–5 mg)
Classification of drugs: upper respiratory combinations

What are Homatropine and Hydrocodone?

Homatropine, as well as hydrocodone, is a combination medication for treating nasal stuffiness, runny noses, sneezing coughs, and sinus congestion due to allergic conditions or the common cold. Homatropine and hydrocodone contain an opioid-based cough medication that can be habit-forming. Hydrocodone and homatropine can also be used to treat conditions not covered in this medication guide.

Side effects of Hydrocodone and homatropine

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, or tongue,

Opioid medication can impede or stop breathing, and even death could occur. Anyone who cares for you should administer Naloxone or seek medical attention if there is prolonged breathing, pauses in your breathing, blue lips, or if it is difficult to get up.

Stop taking hydrocodone and homatropine and contact your doctor immediately if you suffer from:

  • Loud breathing, sighing, and shallow breathing.
  • Extreme tiredness and confusion. Feeling as if you're weak or limp
  • A seizure;
  • A feeling of lightheadedness, as if you've passed out;
  • Extreme constipation; abdominal pain; severe constipation;
  • Very little or no urine;
  • Adrenal gland problems: symptoms include nausea, vomiting, and loss of appetite. Dizziness, fatigue that is worsening, or weakness;
  • Serotonin levels that are high in the body cause hallucinations, agitation, and sweating. High heart rate, shivering muscles, stiffness, twitching, loss of coordination, nausea, diarrhea, and vomiting.

Breathing problems that are serious can be more prevalent in older people and those who are weak or suffer from the syndrome of wasting and chronic breathing conditions.

Common negative side effects of homatropine or hydrocodone can include:

  • Drowsiness, dizziness;
  • Lack of motivation; lack of coordination issues;
  • headache, confusion;
  • dry mouth, nausea, vomiting, constipation;
  • Tremors, irregular or fast heart rate, or
  • Experiencing anxiety, agitation, being anxious, irritable, or nervous.

This is not a comprehensive list of all side effects. Other side effects could be present. Contact your doctor to seek medical advice on the effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


The misuse of this medication could lead to a rise in addiction, overdosing, or even death. Keep the medication in a location where other people are unable to access it.

Side effects that are fatal can occur when you mix this medication in combination with alcohol or with other medications that cause drowsiness or a slowing of breathing.

Before taking this medication

It is not recommended to use homatropine or hydrocodone if you're hypersensitive to homatropine or hydrocodone or if you suffer from:

  • Extremely severe asthma or breathing issues;
  • An upset stomach or obstruction of the bowel (including paralytic ileus);
  • Extreme or uncontrolled; excessive or uncontrolled;
  • Severe coronary arterial pathology (clogged blood vessels);
  • Narrow-angle glaucoma; or
  • If you're unable to urinate,

Never give this medication to anyone under the age of 6 years.

Don't take this medicine in the event that you've used an MAO inhibitor within the last 14 days, including isocarboxazid linezolid blue injections, phenelzine rasagiline, and selegiline. tranylcypromine.

Speak to your doctor if you were ever diagnosed with:

  • Lung disease or breathing issues;
  • A head injury, brain tumor, or seizure;
  • Constipation, an obstruction of the bowel, or stomach-related issues;
  • Problems with your bile drain, pancreas, bile duct, or adrenal glands;
  • An increased prostate;
  • Urination issues;
  • Kidney or liver disease;
  • Lower blood pressure;
  • The heart condition is a blood vessel disorder.
  • A dependence on drugs or
  • If you are suffering from the symptoms of a fever and coughing with mucus,

If you take opioids while pregnant, your baby may develop a dependence on the medication. This can cause life-threatening withdrawal symptoms for the infant after it is born. Babies born dependent on opioids may need medical treatment for several weeks.

Talk to a doctor prior to taking opioids in the case of nursing. Tell your doctor when you experience severe fatigue or a slow breathing rate during the breastfeeding baby's birth.

How to take hydrocodone and homatropine?

Follow the instructions on the prescription label and go through all the medication guidebooks. Don't use this medication in greater quantities or for a longer time than is prescribed. The cold or cough medicines are only meant for use at short-term intervals until symptoms are gone.

Don't share this medicine with anyone else, particularly one who has a history of substance abuse or addiction. A misusing of the medicine can lead to addiction, overdosing, or death. Make sure to keep the medication in a location where other people cannot access it. The sale or distribution of this medicine is against the law.

Make sure to measure the liquid medicine with care. Make use of the dosing syringe supplied or a dose-measuring device (not an ordinary spoon). Cleanse the area after each use.

Consult your doctor if symptoms don't improve after 5 days or if you experience headaches, fever, or a rash, as well as headaches.

If you are in need of an operation or other medical examination, inform the doctor or surgeon prior to the time of your appointment if you have had a cold or cough medicine in the last couple of days.

Storage at room temperature is free of heat and moisture. Don't freeze.

Do not store any medicine leftover. One dose could cause death if someone is using the medicine in error or incorrectly. Read and carefully adhere to the directions included with this medication on how to get rid of any leftover portions.

Details on dosage

Usual Adult Dose for Cough:

One tablet or 5 mL taken orally every 4 to 6 hours, as is
The maximum dosage is 6 tablets, or 30 mL, over the course of 24 hours.

Each tablet has hydrocodone (5 mg) and homotropine (1.5 mg).
Each 5 mL of hydrocodone contains 5 mg of homotropine and 1.5 mg

Use: To relieve symptoms of cough.

Do I be concerned if I miss a dose?

Since hydrocodone and homatropine are taken when required, it is possible that you are not on a prescribed dosage schedule. Do not miss any doses when it's time to take the next dose. Don't take two doses at once.

What will happen if I take excessively?

For medical emergencies, seek immediate attention. You can also dial the Poison Help Line at 1-800-222-1222. A fatal overdose of opioids can cause death, particularly in the case of a child or another person who is taking the medication without a prescription. Overdose symptoms may include severe drowsiness and numbness of the pupils, weak breathing, or a lack of breathing.

The doctor might suggest that you take Naloxone (a medication to treat an overdose of opioids) and carry it around throughout the day. Someone who cares for you may give you Naloxone if you cease breathing or don't wake. Your caregiver needs to get medical assistance in an emergency and might need to administer CPR (cardiopulmonary resuscitation) to you as they wait for assistance to arrive.

Naloxone can be purchased from pharmacies or your local health department. It is important that everyone who cares for you is aware of where you store naloxone and how to utilize it.

What should be avoided?

Don't drink the alcohol. Dangerous side effects or even death could happen.

Beware of operating machinery and driving until you understand the way homatropine and hydrocodone affect your body. Drowsiness or extreme drowsiness could cause accidents or falls.

Interaction with other drugs

You might experience breathing issues or withdrawal symptoms when you begin or stop taking certain medications. Inform your doctor if you are also using medication such as an antibiotic medication, antifungal medicine, blood pressure or heart medicine, medication for seizures, or medication that treats HIV as well as hepatitis C.

Opioid medicine may interact with other medications and can cause deadly side effects or even death. Be sure your doctor is aware if you take:

  • Cold or allergy medications asthma/bronchodilator COPD medication or diuretic ("water pill");
  • Medicines to treat motion sickness and irritable bowel syndrome medications for motion sickness, irritable bowel syndrome, or an overactive bladder;
  • Other opioids, such as pain medication and prescription medicine for cough
  • A sedative such as Valium, diazepam, alprazolam, and lorazepam; Xanax; Klonopin; Versed; and more
  • Substances that cause you to be sleepy or reduce your breathing rate—a sleep pill and a muscle relaxer. Also, medicines to treat mental illness
  • Serotonin-related drugs can alter the levels in your body. They can be stimulants or medications to treat depression, Parkinson's disease, migraine headaches, severe infections, sickness, and nausea.

This list isn't complete. Other drugs can interact with hydrocodone and homatropine, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Not all interactions are included in this list.