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Halobetasol and Tazarotene Topical

Generic name: halobetasol and tazarotene topical [HAL-oh-BAY-ta-sol-and-ta-ZAR-oh-teen-TOP-i-cal]

Brand name: Duoberry
Topical lotion (0.1%–0.045%)
Drug class: topical antipsoriatics

What is Halobetasol and Tazarotene Topical?

Halobetasol is a powerful steroid. Tazarotene has a similar chemical structure to vitamin A.The combination medicine Halobetasol/Tazarotene Topical (for skin) is used to treat plaque psoriasis in adults. This condition causes raised, silvery flaking of the skin and redness.This medication guide does not list all possible uses for halobetasol or tazarotene.

Side effects of Halobetasol and Tazarotene Topical

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing, swelling of lips, face, tongue or throat and difficulty in swallowing (all are signs that an allergy might be developing). Seek medical help immediately.

Topical halobetasol or tazarotene may have serious side effects. If you experience:

  • Itching of the treated skin
  • A sunburn;
  • Vision issues such as blurriness, eye pain or the perception of halos around lights should not be ignored.
  • High sugar; increased thirst; increased urination; dry mouth; fruity breath smell;
  • Possible signs of absorption of halobetasol or tazarotene through the skin include weight gain (especially on your face, upper back, and torso), slow healing wounds, discolored or thinning skin, increased hair growth, muscle weakness, vomiting, or diarrhea. Other symptoms may include fatigue, mood swings, menstrual irregularities, and sexual changes.

Side effects of Halobetasol topical and Tazarotene include:

  • The skin may be irritated, itchy, or swollen.
  • Redness or crusting on your hair follicles.
  • Rash;
  • Peeling skin;
  • Skin thinning is a common problem.

There may be other side effects. For medical advice about side effects, call your physician. To report them anonymously to the FDA at 1-800-FDA-1088.


Topical halobetasol or tazarotene can cause birth defects. Do not use it if you are pregnant. Use birth control to avoid pregnancy.Do not use this medicine if pregnant or if your period is missed.

Before you take this drug

If you have an allergy to halobetasol, tazarotene, or both or are pregnant, you should avoid using this topical.

Tell your doctor about any of the following:

  • Eczema;
  • Any type of skin disease
  • Liver disease
  • An adrenal gland disorder is a condition that affects the adrenal glands.

Steroids can cause glucose levels to increase in the blood or urine. Inform your doctor if you have diabetes.

Halobetasol topical and tazarotene should not be used if you're pregnant. This could cause birth defects or harm to the unborn child. While using this medication, use effective birth control methods to avoid pregnancy.Before starting this treatment, you may need to take a pregnancy test and find out if it is negative. To be sure that you are not expecting, start using the halobetasol/tazarotene cream during your normal period.Do not use this medicine if pregnant or if your period is missed.You may not be able to breastfeed if you are using halobetasol or tazarotene. You should consult your doctor if you are concerned about any risks. Avoid areas where the mouth of a baby may be in contact with this medicine if you apply it to your chest.The use of this medicine by those under 18 is not recommended.

How to take Halobetasol and Tazarotene Topical?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label.Take it only by mouth. Topical medicines are only to be used on the skin.After taking a bath or shower, make sure your skin is completely dry before you apply the lotion.You should wash your hands both before and after you use this medication, unless it is to treat the skin of your hands.Rub a thin layer on the affected area of skin. Do not apply the medicine to a large surface area unless you have been told by your doctor.Use no more than 50 grams of halobetasol or tazarotene in a single week.Cover the treated area only if your doctor says so. Covering the treated area can increase the amount of medicine absorbed by your skin and cause adverse effects.If your symptoms don't improve or worsen, call your doctor.Once your skin symptoms have been controlled, you should stop taking the medication.Store away from moisture or heat at room temperature. Store at room temperature, away from moisture and heat.

Details on dosage

Usual Adult Dose for Plaque Psoriasis:

Once daily, apply a thin layer to the affected areas; stop therapy once control is achieved.
Use: To treat plaque and psoriasis.

What happens if I miss the dose?

If you are close to your next dose, skip the missed dose. Never apply two doses at once.

What happens if I overdose?

If anyone accidentally swallows the medication, seek emergency medical care or call Poison Help at 1-800-222-1222.The use of steroids in high doses can cause thinning of the skin, easy bleeding, changes in body weight (especially on your neck, face, back, and waist), acne, facial hair growth, menstrual issues, impotence, or loss of sexual interest.

What should be avoided?

Use only on areas that are not sunburned, have open wounds, or have eczema. Halobetasol or tazarotene should not be used until the condition has fully healed.Avoid applying topical tazarotene and halobetasol to the face, underarms, or groin. Avoid getting the medication in your mouth, eyes, or vagina.Sunburn may be more likely if you use halobetasol or tazarotene. Avoid tanning beds or sunlight. When you're outdoors, wear protective clothing and use sunblock (SPF 30 or higher).

Interaction with other drug

Tell your doctor about your other medications, including:

  • An antibiotic or any other medication that makes your skin more sensitive.
  • Any other steroid medication used topically, orally, or intravenously

This list is incomplete. Halobetasol topical and tazarotene may be affected by other drugs, including prescription, over-the-counter, and herbal products. This list does not include all drug interactions.