What is Gadoteridol?
Gadoteridol, a contrast agent with magnetic properties, is used to enhance the visibility of blood vessels and organs. The contrast agent is used with magnetic resonance images (MRIs) to make blood vessels, organs, and non-bony tissue more visible. Gadoteridol can be used to diagnose disorders of the brain, spine, and head and neck. This medication guide does not list all possible uses for Gadoteridol.
Side effects of Gadoteridol
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat. Gadoteridol can cause side effects up to a few days after the injection.
Gadoteridol may cause serious kidney damage in patients with advanced disease. If you experience any of the symptoms of this condition, such as:
- Burning, itching, and swelling of the skin are all symptoms.
- Muscle weakness
- Joint stiffness of the arms, legs, or feet
- Deep bone pain in the ribs and hips
- Trouble moving
- Skin redness or discoloration.
Call your doctor immediately if you:
- Kidney problems: little or no urinating; painful or difficult urination; swelling of your ankles or feet; feeling tired or breathless;
- A seizure (convulsions);
- A feeling of lightheadedness, as if you could pass out.
Gadoteridol can cause a number of side effects.
- Nausea;
- Unusual or unpleasant taste in the mouth
There may be other side effects. For medical advice on side effects, call your doctor. Reaching out to the FDA can be done at 1-800-FDA-1088 if any side effects arise from medications.
Warnings
Gadoteridol may cause serious kidney problems in patients with advanced disease. Tell your doctor before receiving gadoteridol if kidney disease is present or if dialysis is needed. Gadoteridol may not be available to you. Tell your doctor if any contrast agents that are similar to gadoteridol have been administered recently.
Before you take this drug
Gadoteridol may cause life-threatening conditions in patients with advanced kidney diseases. This medication should not be taken by people with kidney disease or those on dialysis. Gadoteridol may remain in your system for several months or even years after taking this medication. This medicine is not known to cause health problems in people with healthy kidneys. Tell your doctor that you've had scans using a contrast agent multiple times and give the date of your most recent scan.
Gadoteridol should not be given to someone who is allergic.
Inform your physician of any of the following issues:
- Reaction to contrast agents; * Any kidney conditions
- Diabetes;
- High blood pressure
- Liver disease
- Anemia and Other Red Blood Cell Disorders
- A seizure;
- Asthma; hay; food or drug allergy
- An injury, surgery, or severe infection;
- If you are older than 60,
Notify your doctor immediately if you are pregnant or nursing.
How to take Gadoteridol?
Gadoteridol can be infused into a vein. This injection will be given by a healthcare provider. You may be asked to stay under observation by your doctor or another healthcare provider for a few minutes after the test. Make sure that there are no side effects or delayed reactions with any medication you use.
Details on dosage
Adult dose for CNS magnetic resonance imaging:
Central Nervous System
0.1 mmol/kg (0.22 mL/kg), administered as an intravenous rapid infusion (10 mL/min–60 mL/min) or bolus (greater than 60 mL/min). If scans are negative or ambiguous and the patient is suspected to have lesions that do not enhance well, a second dose of 0.2 mmol/kg (0.40 mL/kg) can be administered up to 30 minutes after the initial dose.
Extracranial and extraspinal tissues:
0.1 mmol/kg (0.22 mL/kg), administered as an intravenous rapid infusion (10 mL/min–60 mL/min) bolus (greater than 60 mL/min).
The usual pediatric dose for CNS magnetic resonance imaging is:
Central Nervous System (CNS): To visualize lesions with abnormal blood vessel vascularity within the brain, spine, and related tissues.
over 2 years old:
0.1 mmol/kg (0.22 mL/kg), administered as an intravenous rapid infusion (10 mL/min–60 mL/min) or bolus (greater than 60 mL/min).
What happens if I miss the dose?
Gadoteridol will only be used during your MRI. You won't have a schedule of doses.
What happens if I overdose?
Overdoses are unlikely because this medication is administered by a health professional in a medical environment.
What should be avoided?
If your doctor prescribes any restrictions regarding food, beverages or activities for you, follow their orders carefully.
Interaction with other drug
Gadoteridol can be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. Informing your physician of all medications you are currently taking and any you discontinue or begin taking is very important.
