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Name of the Generic: Name of the generic: “Tirofiban” [tye-roe-FYE-ban] tye-roe, FYE-ban“tye-roe”
Drug Class: Glycoprotein platelet inhibitors

What is Aggrastat?

Aggrastat can be used to prevent blood clots from forming or heart attacks for those suffering from extreme chest pain or other ailments, as well as for those who undergo a procedure known as angioplasty (to clear blocked vessels). Aggrastat is also employed for other purposes that are not covered in this guideline.

Side Effects of Aggrastat 

Seek medical attention immediately in the event that you exhibit symptoms that are warning signs of an allergic reaction, such as asthma, hives, or swelling of your lips, face, or tongue.

Aggrastat can increase the risk of bleeding, which could be severe or even life-threatening.

Call your doctor or seek medical emergency assistance in the event of:

  • Bleeding or easy bruising (nosebleeds or bleeding gums);

  • Bleeding from the catheter or IV; or

  • Any bleeding that doesn't stop.

There may be bleeding in the interior of your body, for instance, in your intestines or stomach. Contact your doctor immediately. If you experience bloody or tarry stools, or If there is a


of the blood of your vomit, or even make it appear like it appears as coffee ground, This could indicate bleeding in your digestive tract.

Adverse Effects :

  • Dizziness.

  • Low heartbeat;

  • Leg pain, pelvic pain, 

  • Swelling, and increased sweating.

This isn't a complete list of all the side effects. Others could happen. Contact your doctor for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


It is not recommended to take Aggrastat when you are suffering from bleeding that is active in the internal system (stomach or intestines) or have a history of bleeding or blood-clotting disorders, when you've had low blood platelets following receiving treatment by Aggrastat, or were the victim of any procedure, injury, or medical emergency in the last 30 days.

Before you you take this drug

It is not recommended to treat with Aggrastat if you have an allergy to the drug or suffer from any of the following:

  • Any bleeding that is active within the body (stomach or intestines);

  • An antecedent background of bleeding or a blood-clotting disorder

  • If you've had low blood platelets during treatment with Aggrastat or

  • If you've undergone any kind of surgery, injury, or medical emergency in the last 30 days.

Aggrastat is administered as an infusion into the vein. Your healthcare provider will offer the injection. If you take Aggrastat, You may require regular blood tests. Speak to your doctor if you are ever diagnosed with Kidney disease. Speak to your physician if you are expecting or are planning to become pregnant while you are receiving treatment, particularly if you are using aspirin. Do not breastfeed during the course of this medication.

What happens if I miss a dose?

Because you'll receive Aggrastat in a clinical setting, it is unlikely that you'll miss a dose.

What happens if I overdose?

Because this medication is administered by a health specialist in a medical setting, the risk of overdose is less likely to occur.

What should be avoided?

Consult your physician prior to using a nonsteroidal anti-inflammatory medication (NSAID) like ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, and meloxicam, among others. Utilizing an NSAID in the course of or immediately following treatment with Aggrastat could cause bruises or even bleed easily.

Avoid activities that increase the chance of injury or bleeding. Make sure you take extra precautions to avoid bleeding while shaving or brushing your teeth. Avoid drinking alcohol when you are taking Aggrastat. Alcohol can increase your chances of bleeding in the stomach or intestines.

Interaction with other drugs

Inform your doctor about all other medicines you take, particularly:

  • Clopidogrel, ticlopidine.

  • Dalteparin, enoxaparin, and tinzaparin.

  • Desirudin, dabigatran, and fondaparinux.

  • Dipyridamole. 

  • War


    , Coumadin, and Jantoven.

This list isn't exhaustive. Other medications may interact with Aggrastat, which includes prescription and over-the-counter medicines, vitamins, and herbal supplements. The interactions of all drugs are included here.