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Generic name: gadodiamide [GAD-oh-DYE’-a-mide] GAD-oh-DYE-a-mide

The brand names are: Omniscan, Omniscan Prefill Plus, Omniscan Safepak
Dosage form: injectable solution (287 mg/mL)
Classification of drugs: magnetic resonance imaging contrast media

What is Gadodiamide?

Gadodiamide is an agent of contrast with magnetic properties. It is employed in conjunction with magnetic resonance imaging (MRI) to permit organs, blood vessels, and other non-bony tissue to be observed more clearly in the MRI.Gadodiamide helps detect certain diseases of the spine and brain (central nervous system), as well as the chest and stomach regions.Gadodiamide can also be used for reasons not mentioned in this medication guide.

Side effects of Gadodiamide

Contact a medical professional immediately. If you are experiencing symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, or swelling of your lips, face, and tongue,Certain side effects of gadodiamide could occur up to a few days following the injection.Gadodiamide could cause a fatal disease in those suffering from chronic kidney problems. Contact your physician right away if you notice symptoms of this disorder, for example:

  • Irritation, itching, swelling, scaliness, tightening, or the skin's hardening;
    tiredness, muscle weakness;
  • Joint stiffness that affects your hands, feet, legs, or arms;
  • Deep bone pain in your ribs or hips;
  • Problems getting it moving.
  • Skin the skin. Dark patches or redness.

Make sure to contact your doctor at the earliest opportunity if you are suffering from:

  • Kidney problems: no or little urine output, swelling of your ankles and feet, being exhausted or sluggish, and
  • Chest pressure or pain that is spreading to your shoulder or jaw.

Common adverse effects of gadodiamide could include:

  • Headache;
  • Dizziness;
  • Nausea.

This isn't a complete list of all the side effectsContact your doctor to seek medical advice on the effects.Contact your doctor to seek medical advice on the effects.Report any adverse reactions directly to the FDA by calling them at 1-800-FDA-1088.


Gadodiamide could cause a fatal problem in people suffering from severe kidney diseases. It is not recommended to take this medication if you suffer from kidney disease or are taking dialysis.

Prior to using this drug

Gadodiamide could cause a fatal illness in patients suffering from severe kidney diseases. You should not take this drug if you suffer from kidney disease or are on dialysis.Gadodiamide may remain in your body for a number of months or even years after receiving it. It's not clear if this can trigger health issues in those who have functioning kidneys. Inform your physician if you have had multiple scans using an agent that contrasts, and also provide the date of the last scan.Gadodiamide should not be taken by those who are allergic to it.

Inform your doctor immediately if you have experienced:

  • Kidney problems;
  • Any kind of reaction to any contrast agent
  • Diabetes;
  • High blood pressure;
  • Liver disease;
  • Asthma, hay fever, and food or drug allergies
  • An injury, surgery, or severe infection;
  • If you are older than sixty years of age,

Inform your doctor if you are nursing or pregnant.

How do I take Gadodiamide?

Gadodiamide is administered as an infusion into the vein. Your healthcare provider will offer you the injection.Your doctor or health care provider might want to observe your condition for a short period after the test has been completed. This is to ensure that you don't suffer from any adverse or negative side effects or delayed reactions.Gadodiamide may cause unexpected results when used in conjunction with certain medical treatments for up to 24 hours following the MRI. Be sure to inform any physician treating patients that you've had gadodiamide.

Info on dosage

Usual Adult Dose of CNS Magnetic Resonance Imaging:

To detect lesions with abnormal vascularity within the spine, brain, and surrounding tissues:
0.2 mg/kg (0.1 mg/kg) is administered in a bolus intravenous injection.

Usual Adult Dose of Vascular Magnetic Resonance Imaging:

In order to facilitate the visualization of lesions with abnormal vascularization within the abdominal, thoracic, pelvic, and retroperitoneal spaces
Kidney: 0.1 mL/kg (0.05 mmol/kg) given by intravenous injection bolus.
The intra-abdominal, thoracic, and pelvic cavities: 0.2 mL/kg (0.1 mmol/kg) in an intravenous injection in bolus form.

Usual Pediatric Dose for CNS Magnetic Resonance Imaging:

To detect lesions that exhibit abnormal vascularity within the spine, brain, and surrounding tissues:
2 years or older:
0.2 milliliters per kilogram (0.1 mg/kg) given in bolus intravenous injections.

Usual Pediatric Dose for Vascular Magnetic Resonance Imaging:

To aid in the identification of lesions that have abnormal blood flow within the thoracic pelvis, abdominal cavities, and retroperitoneal space
2 years or older:
Kidney: 0.1 mL/kg (0.05 mmol/kg) given by intravenous injection bolus.
Intraabdominal, intra-abdominal, and pelvic spaces: 0.2 mL/kg (0.1 mmol/kg) in an intravenous injection in a bolus.

What happens if I miss the dose?

Because gadodiamide is only used for your MRI and not during your MRI, you won't be following a dose schedule.

What happens if I overdose?

Since the medication is prescribed by a medical specialist in a medical setting, it is highly unlikely for an overdose to occur.

Avoid this 

Follow the instructions of your physician regarding restrictions on food, drinks, foods, or activities.

Interaction with other drug

Other medications may interact with gadodiamide. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your physician about all the medicines you are currently taking as well as any medications you are about to start or stop taking.