What is Florbetapir F 18?
Florbetapir F 18 is a radioactive substance that allows images of certain organs within the human body to be identified using the PET (positron emission tomography) scan. Florbetapir F18 is administered alongside the PET scan to identify the presence of plaque in the brain. Plaque is the accumulation of certain proteins as well as nerve cells with disease that are typically located within the cerebral cortex of people with signs of Alzheimer's disease and other causes of dementia. Florbetapir F 18 can also be used for other purposes that are not mentioned in this guide.
Side effects of Florbetapir F 18
See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, like hives, trouble breathing, and swelling of your lips, face, or tongue,
Common adverse effects of Florbetapir 18 can be:
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Swelling, pain, bruises or irritation at the injection site;
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Headache;
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Joints or muscle discomfort;
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Elevated blood pressure
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Nausea;
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Feeling exhausted.
This list does not comprise all possible side effects and others could occur. Please consult your physician regarding medical adverse reactions and report them directly to the FDA at 1-800-FDA-1088.
Warnings
Receiving a radioactive drug like florbetapir F18 can increase your chance of developing cancer. Discuss with your physician the risk you face.
Before you take this drug
Receiving a radioactive substance could increase the risk of developing cancer.Discuss with your physician any risks you face. Inform your doctor about any medical issues you have. Inform your doctor if you are expecting. You should not feed your baby for the first 24 hours after receiving F-18 florbetapir. If you use an infant pump during this period, discard the milk and don't give it to your child.
How to take Florbetapir F 18?
The drug Florbetapir F 18 is administered into a vein through a healthcare professional. F18 is typically administered 30 to 50 minutes before the PET scan.
Details on dosage
The Usual Adult Dose of Positron Emission Tomography Imaging
370 Mbq (10 mCi) Maximum 50 micrograms mass dose, intravenously, as a single dose with a total volume of 10 mL or less.
Comments This injection should be followed by one intravenous flush of 0.9 percent unsterile sodium chloride.
Utilize PET imaging of the brain for estimating the density of plaques containing beta-amyloid in adult patients suffering from cognitive impairment being examined to determine Alzheimer's disease (AD) and other causes of cognitive decline.
What happens if I miss the dose?
Florbetapir F 18 is prescribed in a single dose and does not come with a daily dose schedule.
What happens if I overdose?
At a medical facility, an overdose is treated immediately.
What should be avoided?
Follow your doctor's advice regarding any restrictions on your food, drink, or activities.
Interaction with other drug
Other medications may interact with the florbetapir F-18 drug, including medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your physician of all medications taken.
