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Flolan

Generic name: epoprostenol E-poe-PROST-en-ol
Brand name: Flolan, Veletri
The class of drug: agents for the treatment of pulmonary hypertension. 

What is Flolan?

Flolan is an example of a prostaglandin (a hormone-like substance that occurs naturally in the human body). Prostaglandins assist in controlling certain processes in the body, like tension in the muscles and blood pressure. Flolan is used to manage the condition of pulmonary arterial hypertension (PAH) and to improve the ability to exercise. Flolan could also be used to treat conditions not mentioned in this medication guide.

Side effects of Flolan

Contact a medical provider immediately if you experience symptoms that suggest allergies, such as hives, breathing difficulty and swelling of lips, face or tongue.

Flolan can cause serious side effects. If any adverse reactions develop, contact your physician immediately - such as:

  • Breathlessness with weakness or dizziness;
  • Feeling dizzy, similar to what happens when passing out;
  • Easily bleeding, unusual bruises;
  • Signs of symptoms of pulmonary edema: anxiety, sweating, pale skin, severe air snoring, wheezing, breathing difficulty, coughing with foamy mucus, chest pain, rapid or irregular heart rate.

Common negative effects of flolan include:

  • Flushing (warmth of redness or tingling sensation);
  • Dizziness;
  • Nausea, vomiting, diarrhea, and stomach pain;
  • Trouble breathing
  • Headache, jaw pain, headache
  • Rapid or slow heartbeats;
  • Muscle or joint muscle joint or muscle;
  • Flu-like symptoms;
  • Feeling nervous or anxious.

This isn't a complete list of possible side effects, and other effects may also be present. Consult a physician if experiencing adverse side effects. Report any side effects directly to the FDA at 1-800-FDA-1088.

Warnings

You shouldn't make use of Flolan when you have lung fluid or heart insufficiency due to a decline in the ability of your heart to return blood to the body.

Before you take this drug

It is not recommended to take Flolan in case you are allergic to the substance or are suffering from:

  • The lungs are filled with fluid (pulmonary edema);
  • Congestive heart failure is caused by a decline in the heart's capacity to return blood to the body.

Ask your doctor about it if you experienced breathing problems when using Flolan.Uncertainty remains as to whether this medication may harm an unborn baby. Please inform your healthcare provider if you plan or expect to become pregnant during treatment with this medication. Breastfeeding while taking this medication could pose risks that should be discussed with your healthcare provider.

How to take Flolan?

Follow the directions on the prescription label and review all medication guides and instructions. Make sure you use the medication according to the directions. It is possible to take Flolan for a long time. The dosage in the clinic or a hospital setting will swiftly take care of any severe reactions. Your heart rate and blood pressure might also need to be checked every time your dose is altered. Flolan is administered using an infusion pump. Usually, it is injected via a permanent central (IV) catheter that is placed in an extensive vein, like inside your chest. Your healthcare professional will administer your first dose and guide you on how to utilize the medication yourself. Take note of and follow the instructions for use that come with your medication, which could differ for different kinds of epoprostenol. Don't take Flolan when you aren't sure of the proper usage instructions. Talk to your pharmacist or doctor for any concerns.

You should prepare your injection only when you are prepared to give it. Avoid using it when the medication is changing color or has particles. Consult your pharmacist about new medications. It is not advisable to stop taking Flolan at a sudden time, even though you feel well. The sudden stoppage of Flolan could increase the severity of your illness. Contact your physician if your symptoms don't improve or if they worsen. To ensure there's no interruption to treatments, it is recommended that you might require a backup infusion pump, battery replacement, and additional IV infusion sets. Make sure you refill your prescription before your supply of medication runs out. Keep flolan powder within its original container, at room temperature, and away from heat, moisture, and light. After mixing the medication, you'll need to take it in some timeframe or days. It will be contingent on the strength of the mix as well as the diluent that you used and whether you keep the mix at room temperature or inside a fridge. Follow the instructions for mixing and storage that are included with your prescription. Should you have any inquiries, don't hesitate to consult your pharmacist.

Make sure that the medicine is protected from direct light throughout the day when it is stored or being used. Make use of a needle and syringe just once, and then put them into a punctureproof "sharps" container. Be sure to follow the laws of your state or city on how to dispose of the container. Maintain a safe distance from pets and children.

What happens if I miss the dose?

Since Flolan is available round-the-clock, you must never miss a dose as long as you take the medication as directed. Contact your doctor immediately in the event that you experience any problems with your Flolan treatment being stopped for reasons beyond your control.

What happens if I overdose?

When medical emergencies arise, immediately seek emergency care or contact the Poison Help Line's toll-free number at 1-800-222-1222 for support.

What should be avoided?

Beware of using an infusion device that hasn't been cleared for use by your physician.

Interaction with other drug

Inform your physician of any other medications you take, including:

  • Diuretic, also known as a "water pill";
  • Blood pressure medication;
  • A blood thinner—warfarin, Coumadin, Jantoven

This list isn't complete. Other drugs can interact with Flolan, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions with drugs included in this list.