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Generical name: Acetaminophen, butalbital, and caffeine; caffeine bue-TAL-bi tal, a-SEET a-MIN- and-KAF-een [a-SEET-a-MIN-ohfen, bue TAL
Drug class: Analgesic combinations

What is Fioricet?

Fioricet capsules include a mixture of acetaminophen, butalbital, and caffeine. Acetaminophen is a pain reliever and a fever-reducing agent. Butalbital is part of a class of drugs known as barbiturates. It eases muscle contractions that are involved in tension headaches. Caffeine is an important central nervous system stimulant. It reduces muscle tension in blood vessels, which improves the flow of blood. Fioricet can be used to treat tension headaches that result from muscle spasms. The use of repeated and extended usage for the treatment Fioricet is not recommended due to the risk of physical dependence.


Fioricet should not be used when you suffer from porphyria or if you've recently taken sedatives, alcohol, tranquilisers, or any other opioids. Avoid using Fioricet if you have taken an MAO inhibitor within the last 14 days. A risky drug interaction may occur. MAO inhibitors are isocarboxazid, linezolid, Methylene Blue injection, phenelzine, and tranylcypromine.

Do not use more Fioricet than is suggested. Acetaminophen overdose may damage your liver or lead to the death of a person. Call your doctor immediately if you experience nausea or pain in your stomach area, itching, or a loss of appetite. black stools, dark urine, and jaundice (yellowing of the eyes or skin). In some cases, acetaminophen could cause a serious skin reaction. Take a break from Fioricet and consult your physician immediately if you notice the appearance of a rash or skin redness that spreads and leads to peeling and blisters.

Before taking this medicine

Avoid using Fioricet if you've taken an MAO inhibitor in the last 14 days. A drug interaction that is dangerous may occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. It is not recommended to use Fioricet. If you are allergic to it, have porphyria, or have recently taken alcohol, sedatives, tranquilisers, or any other opiates,

To be sure Fioricet is suitable for you, inform your doctor if you have ever experienced:

  • Liver disease the cirrhosis, the past history of alcoholism or addiction to drugs, or if you consume more than three alcohol-based drinks every day;

  • Kidney disease;

  • Stomach ulcer or bleeding

  • A history of skin rashes that are caused by medication or

  • An underlying depression or suicidal thought.

It isn't known if Fioricet can harm an unborn baby. If you take butalbital when you are pregnant, the baby could become dependent on the drug. This can cause severe withdrawal symptoms in the newborn after it's born. Children who are dependent on the habit-forming drug might require medical attention for a few weeks. Consult your physician if you are pregnant or planning to become pregnant. Acetaminophen, butalbital, and caffeine can be found in the milk of a nursing baby and could harm the baby who is nursing. Inform your doctor if you are breastfeeding a child. Fioricet is not recommended to be used by anyone younger than 12 years old.

How to take Fioricet?

Use Fioricet exactly as directed. Follow the instructions on the prescription label. Don't take more of this medication than what is suggested. An overdose can damage your liver or cause death. Consult your physician when the medication seems to cease working to relieve discomfort.

Butalbital can be addictive. Don't share this medicine with anyone else, particularly someone who has an addiction history or dependency. Keep the medication in a location where others can't access it. The act of selling or giving away this medication is against the law. Keep at room temperature, free of heat and moisture.

Make a note of the dosage of medicine you take in each new bottle. Butalbital is one of the drugs that can cause abuse, and you should be aware of any person who is using the medicine in a way that is not legal or without having a prescription.

Details on dosage

Usual Adult Dose for Headache:

Butalbital 50 mg, acetaminophen 300 mg, and caffeine 40 mg One or two capsules, orally every 4 hours if needed, not exceeding 6 capsules a day.

Uses: To ease the pain of the symptoms that are caused by a tension (or muscle contraction) headache.

Usual Paediatric Dose for Headache:

12 years and older Age 12 or over: Butalbital 50 mg, acetaminophen 300 mg, and caffeine 40 mg One or two capsules taken orally every 4 hours as required, not exceeding 6 capsules daily


Due to the high level of physical dependence, prolonged use of this drug is not advised.

The safety and effectiveness of treating headaches that are recurring with this product are not yet known. To relieve the tension caused by the complex symptom.

What happens if I miss the dose?

Because this medication is only used in the event of need, you might not be following a dose schedule. If you're following a regimen, take the missed dose as quickly as you can remember. Avoid any missed doses if you are close to the time of the next scheduled dose. Do not take extra medication to replace the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222. A high dose of acetaminophen, butalbital, or caffeine could cause death.

The first symptoms of an acetaminophen overdose include a decrease in appetite, nausea, abdominal pains, sweating, and weakness or confusion. The symptoms that follow may include discomfort in your abdomen, nauseating dark urine, and a yellowing of your skin or the whites of your eyes. Other symptoms of overdose consist of insomnia as well as anxiety, tremors, diarrhoea, irregular heartbeats, seizures (convulsions), or fainting.

What should be avoided?

This medication may result in side effects that can hinder your thinking or reactions. Be cautious if you drive or engage in any activity that requires you to be alert and awake. Do not drink alcohol. It can increase the risk of a liver injury while taking acetaminophen.

Talk to your doctor or pharmacist prior to using any other cold or allergy medication, as well as pain or sleeping medication. Acetaminophen (sometimes abbreviated as APAP) is found in a wide variety of combination medicines. A combination of certain medications could result in excessive amounts of acetaminophen, which could result in an overdose that is fatal. Check the label to determine if the medicine has acetaminophen in it or APAP. When you're using this medicine, try not to use diet pills, coffee pills, or any other stimulants (such as ADHD medication) without consulting your physician.

Side effects of Fioricet

Take immediate medical attention if you exhibit symptoms that indicate an allergy reaction. Fioricet: hives, breathing problems, and swelling of your lips, face, and tongue. In some rare instances, acetaminophen can cause an extreme skin reaction that can turn deadly. This could occur regardless of whether you've previously taken acetaminophen without experiencing any reactions. Do not take this medication and contact your physician right away in the event of an itch or redness on your skin that spreads and leads to blisters or flaking. If you have this kind of reaction, you shouldn't ever again use any medication that contains acetaminophen. Stop taking this medicine and consult your physician immediately. If you are suffering from:

  • Confusion,

  • A seizure;

  • Breathlessness;

  • A euphoric feeling, similar to passing out or

  • Nausea, abdominal pains, itching nausea, loss of appetite, stool, black or clay-coloured urine, jaundice (yellowing of the eyes or skin),

Common side effects of Fioricet include:

  • Drowsiness,

  • Dizziness;

  • Feeling lightheaded

  • Nausea

  • Vomiting

  • Stomach pain

  • Drunk feeling

  • Breathlessness

This isn't a complete list of all the side effects. Other side effects could be experienced. Contact your doctor for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs


Combining this medication with other medications that cause you to sleep or cause breathing problems could result in life-threatening or dangerous adverse consequences. Ask your doctor prior to taking Fioricet together with a sleeping medication, opioid pain medicine, muscle relaxer, or medication to treat anxiety, depression, or seizures.

Other medications can be incompatible with acetaminophen, butalbital, and caffeine, which include prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your doctor all the other medications you are taking.