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Fexofenadine and pseudoephedrine

Generic name: Fexofenadine and pseudoephedrine [FEX-ah-FEN-a-deen and SOO-dooee FED-rin] should only be combined if both substances have been prescribed together as prescribed medications for medical conditions that require fever medication such as flu or cold symptoms.
Brand names: Allegra-D 12 Hour, Allegra-D 12 Hour Allergy and Congestion, Allegra-D 24 Hour Allergy and Congestion, Antihistamine and Nasal Decongestant, Fexofenadine HCl-Pseudoephedrine 12 Hour, Allegra-D 24 Hour, Allegra-D OTC 24HR
Form of dosage: oral tablet, extended release (180-240 mg or 60-120 mg).

What is Fexofenadine and pseudoephedrine?

Fexofenadine reduces the effects that the natural chemical histamine has on the body. Histamine can cause symptoms such as sneezing and itching. Watery eyes and runny or watery nasal discharge may also result. Pseudoephedrine acts as a nasal decongestant by constricting blood vessels that become dilated due to congestion in the nasal passages. Dilated vessels cause congestion. Combination medicine containing fexofenadine (as well as pseudoephedrine) is used to treat symptoms such as sneezing or runny nose, watery or itchy eyes, hives or skin rash, and itching. This medication guide does not list all possible uses of fexofenadine or pseudoephedrine.

Side effects of Fexofenadine and pseudoephedrine

If you experience any of the following signs of an allergic reaction: difficulty breathing, hives or swelling on lips, face, tongue and throat. Please seek medical help immediately!

Fexofenadine or pseudoephedrine can cause serious side effects. If you experience:

  • If you feel your heart fluttering or pounding, then this is what it means.
  • Severe dizziness or anxiety. Restlessness, tremors, and nervousness

Side effects of pseudoephedrine and fexofenadine include:

  • Mild dizziness;
  • Dry mouth, nose, or throat
  • Nausea;
  • Sleep problems (insomnia).

There may be other side effects.Call your doctor if experiencing side effects. For medical advice regarding adverse reactions.The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Warnings

If you've taken an MAO inhibitor in the last 14 days (such as isocarboxazid or linezolid), phenelzine rasagiline, selegiline, or tranylcypromine, do not take fexofenadine.

Before you take this drug

If you've taken an MAO inhibitor within the last 14 days, don't take fexofenadine or pseudoephedrine. A dangerous drug-drug interaction may occur. MAO inhibitors are isocarboxazid (linezolid), methylene blue injection, rasagiline, and selegiline.

If you suffer from:

  • Kidney disease
  • Glaucoma;
  • High blood pressure or heart disease?
  • Diabetes;
  • Thyroid disorder;
  • Other urination issues or bladder obstruction.

The safety of fexofenadine or pseudoephedrine for an unborn child is unknown. Consult your doctor if you're pregnant before taking this medication. Pseudoephedrine may pass into breastmilk and cause side effects for the nursing infant. Consult your doctor before taking this medication if you're breastfeeding.Do not give this medication without first consulting with a pediatrician.

How to take Fexofenadine and pseudoephedrine?

Do not exceed the recommended dosage or duration. Use the recommended dose or duration. Do not exceed it. Cold and allergy medication is typically taken for only a few days until symptoms disappear. This medication should not be given to children younger than two years of age. Ask a doctor first before giving cough or cold medication to your child. Children as young as 2 years old can die from the misuse of cough medicines. No longer chew or crush the extended-release tablets. Take it as a whole. Take the fexofenadine/pseudoephedrine at least an hour before a meal or two hours after. Avoid fruit juices, especially orange, apple, or a data-type="auto" Avoid juices such as orange, apple, or grapefruit juice. Fruit juices can interfere with the absorption of fexofenadine by your body. If your symptoms don't improve within 7 days or you experience a fever, headache, cough, or rash, call your doctor. Tell your doctor or surgeon if you've taken allergy or cold medicine in the last few days.Store at room temperature away from heat and moisture to extend their shelf life.

Details on dosage

Adult dose for Allergic Rhinitis:
Orally, take 1 tablet (60–120 mg) every 12 hours.
Maximum dose: 2 tablets per 24 hours.
The usual pediatric dose for allergic rhinitis is:
12 years of age and older: Take 1 tablet (60–120 mg) every 12 hours.
Maximum dose: 2 tablets per 24 hours.

What happens if I miss the dose?

You may not have a regular schedule of dosages since cold and allergy medication is usually taken only when needed. Take the missed dose immediately if you take the medication regularly. If your next scheduled dosage is approaching, skip the missed dose. You should not take more medicine to compensate for a missed dose.

What happens if I overdose?

Contact 1-800-222-1222 immediately in case of poisoning and receive professional assistance immediately, or seek immediate medical treatment from professionals.

What should be avoided?

Avoid taking antacids 15 minutes before or right after you take fexofenadine or pseudoephedrine. Antacids may make it difficult for your body absorb this medication. Before using any other cold or allergy medication, consult your doctor or pharmacist. Many combination medications contain pseudoephedrine. You can get too much fexofenadine or pseudoephedrine by taking certain products together. Certain side effects can be exacerbated by alcohol consumption.

Interaction with other drug

This medicine can have a worse effect if taken with drugs that cause you to sleep or slow down your breathing. Before taking fexofenadine or pseudoephedrine along with sleeping pills, narcotic pain medicines, muscle relaxers, or medicines for anxiety, depression, or seizures, ask your doctor. Other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal supplements, may also interact with fexofenadine or pseudoephedrine. Inform your healthcare providers of all the medicines you are currently taking and those you plan to start using.

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