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Elestrin

Generic name: estradiol topical (for use on skin) [ess-tra-DYE-ol-TOP-ik-al]

Brand name: Elestrin Pump
Drug class: estrogens

What is Elestrin?

Elestrin contains estradiol 0.06 percent in a non-staining, colorless gel, which is supplied in a non-aerosol metered-dose pump bottle. Estradiol is a kind of estrogen, which is a female sex hormone that is produced by the ovaries. It is responsible for controlling a number of processes within the body.Elestrin is prescribed after menopausal changes to decrease extreme to moderate hot flashes.

Elestrin contains estradiol 0.06 percent in a non-staining, colorless gel, which is supplied in a non-aerosol metered-dose pump bottle. Estradiol is a kind of estrogen, which is a female sex hormone that is produced by the ovaries. It is responsible for controlling a number of processes within the body.Elestrin is prescribed after menopausal changes to decrease extreme to moderate hot flashes.The ovaries stop producing estrogens whenWomen aging between 45 to 55 are generally classified as middle aged.The drop in estrogen levels in the body can trigger an occurrence known as the "change of life" or menopausal changes (the ending of menstrual cycles). As estrogen levels start to decrease, some women experience uncomfortable symptoms, including a feeling of warmth around the neck, face, and chest, or intense feelings of heat, as well as sweating ("hot flashes"). For some women those who experience mild symptoms and they do not require estrogens. In some women, symptoms may be more severe, and treatment with products like elestrin could assist.

Side effects of Elestrin

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction to Elestrin: hives; difficulty breathing; and swelling of your lips, face, and tongue,

Stop taking Elestrin and consult your physician immediately if you suffer from:

  • Symptoms of a heart attack symptoms: chest pain, pressure, discomfort spreading to your shoulder or jaw, nausea, sweating, or vomiting;

  • Symptoms of an enlargement of blood that cause sudden numbness, weakening of the vision, sudden loss of speech, slurred speech, or chest pain. Sweating, blood, warmth, or pain either in the legs or one;

    tenderness or swelling in your stomach; stomach pain that extends into your back; nausea and vomiting

  • Jaundice (yellowing of the eyes or skin);

  • Memory problems and confusion, as well as unusual behavior;

  • Abnormal vaginal bleeding that has not been checked by a physician;

  • A mass in your chest or

  • High levels of calcium cause fatigue, confusion, nausea, vomiting, constipation, a lack of appetite, and increased thirst and weight loss.

Topical estradiol can be absorbed through the skin of children who are exposed to the medicine. Call your doctor if a child who is in frequent contact with you develops swelling in the nipples of their nose or breasts that are larger.

Common elestrin side effects can include:

  • Discomfort in the breast;

  • Headache;

  • Vaginal discharge or itching vaginal discharge or itching, menstrual cycle changes vaginal bleeding that is light or bleeding;

    thin hair on the scalp;

  • Nausea, vomiting, bloating, and stomach cramps.

This list does not encompass all possible side effects; others could arise. Please seek medical advice from your physician regarding their effects, and report adverse reactions directly to FDA at 1-800-FDA-1088.

Warnings

It is not recommended to use this medication if you suffer from undiagnosed vaginal bleeding or bleeding disorders, liver disease and a higher risk of blood clots in the event of major surgery, or have had an attack of the heart, stroke, blood clot, as well as cancers of the breast, uterus/cervix, or vagina.

Do not apply elestrin gel if expecting.

Estradiol can increase your risk of developing a disease that could cause uterine cancer. If you notice any bleeding from your vagina, that is unusual.

Utilizing estrogen could increase the risk of stroke, blood clots, heart attack, and cancer of the uterus, breast, or ovaries. Estradiol should not be used to stop stroke, heart disease, or dementia.

Estradiol topical can be absorbed through the skin. It can cause adverse effects for the child who comes into contact with the skin after you've applied the gel.

Elestrin should not be used. If you suffer from:

  • Abnormal vaginal bleeding that has not been checked by a physician;

  • Any kind of cancer of the uterus, breast, or hormone-dependent cancers

  • An antecedent previous history of heart attack, stroke, or blood clots (especially in your lungs or lower part of your body);

  • Liver disease;

  • A bleeding or blood-clotting disorder;

  • If you believe you may be pregnant or could potentially become pregnant, here is some essential advice:

  • If you've ever experienced any allergic reactions to estradiol in the form of a topical,

Estradiol does not stop heart disease, heart attacks, breast cancer, stroke, or dementia.Increased exposure may increase the risk of disease development. Estradiol can also increase the chance of getting ovarian or uterine cancer. Consult your doctor regarding your specific risk.

To ensure that elestrin is not harmful to you, inform your doctor. If you are suffering from:

  • Unusual vaginal bleeding

  • Heart disease;

  • Asthma;

  • Epilepsy or another seizure disorder;

  • Kidney or liver disease;

  • Hereditary angioedema

    endometriosis;

    an thyroid disorder;

  • Lupus;

  • The calcium levels are high in the blood (hypercalcemia);

  • Migraines;

  • Gallbladder diseases;

  • Risk factors that can lead to coronary artery diseases (such as smoking, diabetes, being overweight, excessive blood pressure, cholesterol, or an ancestral connection to coronary artery diseases, being over 40 years old, or having been through an hysterectomy)

Do not take Elestrin in the event that you are expecting. Use effective birth control when taking this medication in order to avoid pregnancy.Estradiol may be absorbed into the breastmilk of a baby and could harm nursing babies.Breast-feeding can also reduce production of milk.

Similar or related drugs

Estradiol, Premarin, Estrace, Prempro, and Estrogel

How to take Elestrin?

Make sure you use Elestrin exactly as directed by your physician. Follow the directions on the prescription label. Do not take this medication in greater or lesser quantities or for longer than prescribed.Estradiol could increase your chance of developing a condition that could cause uterine cancer. Your doctor could prescribe progesterone in conjunction with estradiol to lower the risk. If you notice any vaginal bleeding that seems unusual immediately,Elestrin includes patient instructions to ensure the safest and most effective use of the drug, as well as instructions on starting your gel pump. Follow these steps carefully. Talk to your pharmacist or doctor for any additional questions.

  • Apply elestrin only to dry, clean, and unbroken skin. Avoid applying it to skin that is sensitive or red.Do not apply this medication directly to the breasts.

  • Elestrin is applied daily over the arms' upper portion via a metered-dose pump that releases 0.87 grams of Elestrin gel per activation. Dosage should start by using the lowest dose of elestrin, which is one pump daily. A subsequent dose adjustment can be made based on the response. The dosage should be regularly reviewed by your healthcare professional. Make sure to take the gel at the same time every day.

  • Don't rub gel with elestrin in, but let the gel sit on your skin for at least five minutes prior to putting on your clothes.

  • Cleanse your hands using detergent and soap after using the gel. Beware of allowing others to rub this medicine on their faces. If this happens to you, wash the area thoroughly using soap and water.

Children should not come into contact with areas of the skin to which you've applied elastrin. The topical estradiol is absorbed through the skin and may cause premature puberty for a child who comes into contact with the medicine or the skin areas where the medication was applied. Cover treated areas with clothing to prevent others from getting in close contact with your skin after the medicine is applied.Your physician should examine your improvement regularly (every 3 to six months) to determine if you are able to continue with this treatment. Check for any lumps or bumps in your breasts at least once a month, and get regular mammograms when you are taking estradiol.If you are in need of medical or surgical procedures or are bedridden, then you might need to stop taking this medication for a brief period of time. Any surgeon or doctor who cares for you must know that you're taking estradiol.Keep elestrin in a cool, dry place, away from heat and moisture.

What happens if I miss the dose?

Make sure to take any forgotten dose as soon as you become aware. If it has been more than 12 hours since your last scheduled dose, take a break before making up any missed ones with extra medication. Doing this could result in potentially harmful side effects.

What happens if I overdose?

For medical emergencies, seek immediate attention. Or contact emergency medical attention or call the Poison Help Line at 1-800-222-1222. Overdose symptoms can include vomiting, nausea, breast tenderness, and stomach pain, as well as drowsiness and vaginal bleeding.

What should be avoided?

Avoid getting elestrin gel in your eyes. If this happens, wash your eyes with water.At least 25 minutes following the application of elestrin before applying sunblock to that area.Grapefruit juice and grapefruit can interact with estradiol, leading to potentially hazardous consequences. Talk about the use of grapefruit juice with your doctor.

Interaction with other drug

Other drugs can be incompatible with estradiol topical, which includes prescription and non-prescription medications, vitamins, and products made from herbs. Inform all of your health care professionals about any medications you are taking currently and all medicines that you decide to stop or begin taking.

The drop in estrogen levels in the body can trigger an occurrence known as the "change of life" or menopausal changes (the ending of menstrual cycles). As estrogen levels start to decrease, some women experience uncomfortable symptoms, including a feeling of warmth around the neck, face, and chest, or intense feelings of heat, as well as sweating ("hot flashes"). For some women those who experience mild symptoms and they do not require estrogens. In some women, symptoms may be more severe, and treatment with products like elestrin could assist.