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Name of the generic: Elapegademase [El-a-peg-AD e-mase] [ EL-a-peg-AD-emase

Name of the brand: Revcovi
Dosage form: Intramuscular solution (LVLR 1.6 mg/mL)
Classification of drugs: Other immunostimulants

What is Elapegademase?

Ela Pegademase is a synthetic form of an enzyme known as adenosine deaminase (ADA). ADA is essential in the body to stop the accumulation of harmful proteins in your white blood cells, which aid in fighting infections.Ela Pegademase is a drug used to replace ADA for children and adults with severe adenosine deaminase combined immunodeficiency (ADA-SCID).ADA-SCID refers to an inability to fight infections that aren't likely to cause illness in people who have a healthy immune system. Certain diseases (such as the common cold, chronic diarrhea, or severe skin eruptions) could be severe or even fatal to those who suffer from ADA-SCID.The ADA-SCID may also affect the development or growth of an infant or a young child with this condition.Ela Pegademase can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Elapegadema

Contact a medical professional immediately. If you are experiencing warning signs of an allergic response, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, and tongue,

Elapegademase may cause serious side effects. Contact your physician immediately. If you suffer from:

  • Bleeding at the site where the injection was made;
  • Other unusual bleeding (nosebleeds or bleeding gums);
  • A seizure;
  • Yellowed, pale skin, dark-colored urine,
  • Insecurity or confusion.

The symptoms listed below could be indicators of an infection that could indicate that elapegadema may not be the best treatment for you. Inform your physician if you are suffering from:

  • Fever, chills, unusual tiredness;
  • A sore throat, sinus discomfort, and swollen glands
  • Inflammation or skin warmth;
  • Digestive cramps; diarrhea, vomiting, or diarrhea;
  • The presence of blood in your urine or stools
  • Urination that is painful or difficult
  • Breathing issues, cough with mucus;
  • White patches or sores that appear either on the skin or in your mouth
  • Issues with balance or walking problems with balance or walking.
    Dental issues or gums.

Common adverse effects of el pegademase could include:

  • Vomiting;

This isn't a complete list of possible side effects, and other side effects could occur. Contact your physician to seek medical advice on the effects.Report any adverse reactions directly to the FDA at 1-800-FDA-1088.

Similar/related drugs



Follow the directions on the label of your medication and on the label of your package. Be sure to inform your health care providers about your medical issues, allergies, and the medicines you are taking.

Before you take this drug

Discuss with your physician if you have ever taken the medication known as Adagen (pegademase bovine).Inform your doctor if you have experienced serious thrombocytopenia (a low level of platelets in your blood).Your physician should examine your health frequently when you are taking elapegademase during pregnancy.It is not always appropriate to breastfeed while taking ela pegademase. Consult your physician about any risks.

How to take  Elapegademase?

Follow the directions on the label of your prescription and study all medication guides or instructions sheets. The doctor might alter the dosage. Make sure you take the medication exactly as prescribed.Ela Pegademase can be injected into the muscle. Healthcare professionals can instruct you on how to correctly apply the drug yourself.Ela Pegademase is typically prescribed every seven days. Follow your doctor's dosage instructions with care.Take note of and follow the instructions for use that come along with your medication. Consult your physician or pharmacist for clarification if you aren't sure about the instructions.Make an injection only once you are ready to administer it. Avoid using it when the medication appears cloudy, changes color, or has particles. Consult your pharmacist about new medications.The doses of ela pegademase are based on weight. Your dose needs may change as you gain or lose weight.There is a chance that you will require frequent medical tests. Even if there are no symptoms, tests can aid your doctor in determining the effectiveness of this treatment.It can take anywhere from 2 to 6 months before you experience the full benefits of the drug elapegademase. Make sure to take the medication as often as you can for the best results.Don't shake the medication bottle, or you could ruin the medication.Keep it in the refrigerator; don't freeze it. Recycle the medication if it's been frozen.The contents of each throughl (bottle) are intended for only one usage. It is discarded after just one usage, even if there's still medicine within.Make use of a needle or syringe once only and place them into a puncture-proof "sharps" container. Make sure you follow local or state laws on how to dispose of the container.Keep it out of reach of pets and children.

What happens if I miss the dose?

Contact your doctor for advice in case you missed a dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222. 

What should be avoided?

Beware of those who are sick or suffer from infections. Inform your doctor immediately when you begin to show symptoms of an infection.Avoid activities that could increase the chances of sustaining injuries or bleeding. Make sure you take extra precautions to prevent bleeding when shaving or brushing your teeth.

Interaction with other drugs

Other medications can influence ela pegademase, like prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about the medicines you are currently taking and any medication you begin or stop taking.