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Generical name: ecallantide [e-KAL-an-tide]
Name of the brand: Kalbitor
Dosage form: subcutaneous solution (10 mg/mL)
Classification of drugs: hereditary angioedema agents

What is Ecallantide?

Ecallantide helps treat symptoms that are caused by hereditary angioedema (an immune system disorder). Ecallantide can be used in adults and children who are at least 12 years old.Ecallantide cannot be used as a treatment to treat hereditary angioedema.Ecallantide may also be taken for purposes not specified herein. Please consult a healthcare provider if additional use of this medication is desired.

Side effects of Ecallantide

Ecallantide may cause serious allergic reactions within 1 hour after the injection. Tell your caregivers immediately if you suffer from:

  • Chest tension or pain; rapid or weak heartbeats;
  • Wheezing, cough, throat irritation trouble breathing
  • Hoarse voice, a tightness within your throat, difficulties swallowing
    swelling of your tongue, lips, or throat;
  • The appearance of redness or swelling on your face;
  • The itching, rash, or hives;
  • Flushing (warmth of redness or tingly sensation);
  • Snorting, stuffy, or runny nose;
  • Dizziness, feeling like you might pass out.

A reaction to an allergic substance may exhibit identical symptoms as angioedema caused by hereditary factors. Your healthcare providers will be watching you closely and quickly dealing with any allergic reactions.

Common negative side effects of ecallantide can include:

  • Headache;
  • Nausea, diarrhea;
  • Fever;
  • Stuffy nose or sore throat and
  • Skin reactions that occur when the medicine is injected (redness, itching, rash, and swelling).

This isn't a complete list of possible side effects, and other side effects could be present. Consult your physician to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Ecallantide may cause an extremely allergic reaction within one hour of injection. Symptoms include wheezing and coughing, difficulty swallowing or breathing, itching, hives, fainting, or swelling of your throat or face.

Prior to use this drug

If it is possible to do so in an emergency, inform your family members that you have any kind of allergic reaction. Be sure that any doctor who follows up is aware that you have received ecallantide.If you are able to do so during an emergency, inform your medical professionals if you're nursing or pregnant.

How to take Ecallantide?

Ecallantide can be injected under the skin by a health practitioner, typically in three distinct injections.You will be closely monitored to ensure that you don't suffer from an allergic reaction to the medication.If you are still experiencing symptoms of angioedema after three injections, a further one could be administered within the next 24 hours.

Details on dosage

Usual Adult Dose for Hereditary Angioedema:

Subcutaneously, 30 mg, in three 10 mg injections. could repeat 30 mg over the course of 24 hours if the problem persists.

Usual Pediatric Dose for Hereditary Angioedema:

12 years or older Subcutaneously: 30 mg with three injections of 10 mg, and you may repeat the injections with 30 mg in the next 24 hours if the attack continues.

What happens if I miss the dose?

In a medical environment, you will not be prone to skip the dose.

What happens if I overdose?

In a medical facility, the overdose is immediately treated.

What should be avoided?

Follow your doctor's advice regarding any restrictions on your food, drink, or any activity.

Interaction with other drugs

Other medications may interact with Ecallantide's effects, such as prescription or other over-the-counter medications, vitamins, and herbal products.Inform your physician about any other medications you take.



Prescription only

Pregnancy & Lactation

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