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Dutasteride

The Generic Name: Dutasteride [doo-TAS-ter-ide Doo-TAS-ter ide].
Brand Name: Avodart.
Dosage Form: Oral capsule (0.5 mg).
The Class of Drugs: 5-alpha-reductase inhibitors.

What is Dutasteride?

Dutasteride is a treatment for benign prostate hyperplasia (BPH) in males with an increased prostate. Dutasteride can improve the flow of urine and could also lessen the necessity for surgery in the future. Dutasteride is intended for men only. Dutasteride can also be used for other purposes that are not covered in this guideline.

Side effects of Dutasteride

Seek medical attention immediately. If you notice symptoms warning signs of a reaction (hives or breathing difficulties and swelling in your throat or face) or a severe reaction to your skin (fever and throat soreness, eye burning, irritation, as well as red or purple itching, blisters, and peeling),

Common adverse effects of dutasteride could be:

  • Lower sexual desire (sex driving).
  • Reduced amount of semen released during sex.
  • Impermanence (trouble in obtaining or maintaining an erection).
  • Breast tenderness or an increase in size.

Sexual side effects associated with dutasteride could persist even after stopping this medication. Discuss this with your doctor if you are concerned about these adverse effects. This isn't an exhaustive list of possible side effects, and other side effects could occur. Contact your doctor if you are experiencing any side effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Warnings

Dutasteride is not recommended for use by women or children. Dutasteride could cause birth defects in women who are pregnant and exposed. Dutasteride capsules should never be used by women who are pregnant or could be pregnant.

Before you take this drug

Dutasteride is not recommended when you are allergic to the dutasteride ingredient or finasteride. Dutasteride should not be consumed by a woman or child. Dutasteride is absorbed through the skin. Women or children should not be allowed to handle capsules of dutasteride.

Speak to your doctor if you have ever suffered from:

  • Liver disease.

The use of dutasteride could increase the chances of developing prostate cancer. Your doctor will check your prostate-specific antigen (PSA) to determine if you have cancer when you take this drug. Dutasteride is not recommended for use by women. The medication can cause birth defects in women who are pregnant and exposed. Dutasteride capsules shouldn't be used by women who are pregnant or might be pregnant. If a woman happens to come into contact with the medication through a leaky capsule, clean the area thoroughly with water and soap immediately.

How to take Dutasteride?

Your doctor will run tests to confirm that there are no other medical conditions that could hinder you from using dutasteride. Follow the directions on the prescription label and read the medication guide or instructions sheets. Make sure you use the medication exactly as prescribed. The medicine should be taken every day, either with or without eating. Suck the capsule whole, and don't crush or chew on it, break it, or break it open. It could take six months or more before you are able to reap the full benefits that dutasteride provides. Your doctor will decide how long they will treat you with this medication. Use the medication exactly according to the directions. You'll need to undergo frequent medical examinations. Place the bottle in a cool, dry place far from heat, moisture, and light. Make sure the bottle is tightly sealed when not in use.

Details on dosage

Usual Adult Dose for Benign Prostatic Hyperplasia:

0.5 mg taken orally, once a day
Treatment of benign prostatic hyperplasia symptomatic (BPH) in males with an increased prostate size to lower the chance of developing chronic urinary retention (AUR) and BPH-related surgeries.

What happens if I miss a dose?

You should take the medication as quickly as you are able, but do not take any missed doses if it's close to the time of the next dose. Don't take two doses at once.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Do not give blood to anyone when you are taking dutasteride. You should wait at least six months after your treatment is over. Dutasteride may be absorbed into the bloodstream and may cause birth defects in pregnant women who receive a blood transfusion that contains dutasteride.

Interaction with other drugs

It is sometimes not safe to take certain medicines simultaneously. Certain medications can alter the blood levels and the other drugs you are taking, which could create side effects or render the medication less effective. Other medications can affect dutasteride's effects, including prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician your current medications as well as any medications you are about to start or stop taking.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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