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Doribax

Drug class: carbapenems

What is Doribax?

Doribax is an antibiotic that combats bacteria. Doribax can be used to treat severe stomach, bladder, or kidney infections. Doribax can be used in other ways not mentioned in this guide.

Warnings

Doribax should not be given to anyone who is allergic to doripenem or any of the other drugs: ertapenem, imipenem (Primaxin), meropenem, and ertapenem. Tell your doctor about any kidney problems, seizures, or allergies to penicillin antibiotics. Tell your doctor if probenecid and valproic acids are also used. If you experience a severe rash or have diarrhea that is bloody or watery, call your doctor immediately.

Before you take this drug

Doribax should not be used if you have an allergy to doripenem, imipenem (Primaxin), ertapenem, or meropenem.

Tell your doctor about any of the following to ensure that Doribax will be safe for you:

  • Kidney disease
  • A history of strokes or seizures;
  • A history of penicillin allergy, such as Amoxil (Augmentin), Bactocill (Bicillin L-A), Dycill (Dynapen), Moxatag (Omnipen), Principen PC Pen, VK Pfizerpen Ticar Timentin Unasyn and others

Doribax should not harm an unborn child. Inform your doctor if you are pregnant or planning to become pregnant while on treatment. It is unknown if doripenem can pass into breast milk or if a nursing infant could be harmed by it. You should tell your doctor if a child is breastfed.

Similar/related drugs

Amoxicillin, Doxycycline, Ciprofloxacin, Cephalexin, Metronidazole, Clindamycin, and Augmentin

How to take Doribax?

Doribax should be taken exactly as prescribed by your physician. Please follow all the instructions on the prescription label. Use this medication only as directed.Do not exceed the suggested dose and use over an extended period. Doribax can be injected through an IV into a vein. You may be taught how to use an intravenous catheter at home. You should not inject this medicine yourself if you don't know how to properly give the injection or dispose of used needles and IV tubing. Doribax can be given for 5 days up to 2 weeks, depending on the condition. After the first few weeks of receiving doripenem as an injection, you may be switched to a pill form (oral antibiotic). Doribax comes as a powder and must be mixed (diluent) with liquid. Before using the mixture, you will need to put it in an IV bag with an infusion solution. You should know how to mix and store your injections if you use them at homeShould you have any inquiries, don't hesitate to ask your pharmacist.

Do not discontinue taking your medication before it has completely cleared, since symptoms could surface before your infection has completely subsided. You may increase your chances of a second infection resistant to antibiotics if you skip doses. Doribax does not treat viral infections such as the flu or the common cold. You can store the mixture at room temperature or in the refrigerator after mixing it with the IV infusion solution. Do not freeze. If your infusion is 5% dextrose or normal saline, you can store the mixture at room temperature for up to four hours. In the refrigerator, you can store your mixture for up to 72 or 24 hours, depending on whether your infusion is 5% dextrose. Doribax is not preservative-free. Doribax should be thrown away if it is not used in the specified number of hours, based on the storage solution and your infusion method.

What happens if I miss the dose?

If you forget to take a Doribax dose, call your doctor.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Antibiotics can cause diarrhea. This could be an indication of a new illness. Doribax should be stopped if you experience diarrhea that is bloody or watery. Call your doctor. You should only use anti-diarrhea medication if your doctor has prescribed it.

Side effects of Doribax

If you experience any of the following symptoms of an allergic reaction: hives, difficulty breathing, swelling of your lips, face, or throat, please seek emergency medical attention.

If you experience:

  • Severe stomach pain;
  • Diarrhoea that is bloody or watery
  • Itching and skin rashes can be severe.

Doribax may cause side effects such as:

  • Headache;
  • Diarrhea, nausea;
  • Vaginal itching and discharge
  • Mild rash
  • Pain, swelling, or redness at the injection site.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Tell your doctor if you are taking any other medications or if you will stop taking them during treatment with Doribax.

  • Probenecid;
  • Valproic acid

This list is incomplete. Doribax may interact with other drugs, including prescription, over-the-counter, herbal, vitamins, and other products. This medication guide does not list all possible interactions.