What is Desmopressin nasal?
Desmopressin, a manmade version of a naturally occurring hormone in the pituitary, is produced by humans. This hormone regulates water use, blood pressure, and kidney function. The nasal form of desmopressin is used for the treatment of central cranial diabetes insipidus and increased thirst or urination due to head trauma or surgery. Stimate medication is used to treat bleeding in patients with hemophilia A and von Willebrand disease type I. Noctiva can be used to treat excessive nighttime urination among adults aged 50 and older. Noctiva is not recommended for treating nighttime bedwetting. This medication guide does not list all possible uses of desmopressin nasal.
Side effects of Desmopressin nasal
If you experience any of the following signs and symptoms of an allergic reaction: difficulty breathing, hives or swelling to face lips throat and face
Desmopressin may cause serious side effects. If you experience:
- Signs of low sodium: headache, confusion, hallucinations, muscle pain, weakness, or drowsiness. Also, nausea, vomiting, and feeling restless
- Rapid weight gain and swelling of the ankles or feet;
- A seizure (convulsions);
- Nasal problems: runny nose or sinus congestion.
Children and older adults are more susceptible to low sodium.
Desmopressin can cause the following side effects:
- Stuffy nose, runny nose, sinus pain, sneezing, and discomfort in the nose
- Sore throat and cough
- Dizziness;
- Increased blood pressure
- Nausea, stomach cramps;
- Back pain and headaches
- Flushing (warmth, redness, or tingly sensation)
There may be other side effects.Call your physician immediately if experiencing side effects; for medical guidance on reporting them contact 1-800-FDA-1088 or reach out directly.
Similar/related drugs
hydrochlorothiazide, tranexamic acid, imipramine, desmopressin, microzide, vasopressin, and DDAVP
Warnings
Limit your water intake and other fluids. Too much water may cause you to lose sodium and electrolytes, which can be life-threatening. When certain medications are taken together, serious drug interactions may occur. You should tell your doctor if you are also taking steroid or diuretic medicine. If you experience any of the following symptoms of low sodium: headache, confusion or muscle pain, nausea, loss of appetite, or feeling drowsy, call your doctor immediately.
Before you take this drug
If you have an allergy to desmopressin, then desmopressin should be avoided.
You may not be able to use desmopressin if you:
- A history of hyponatremia (low sodium levels within your body);
- Uncontrolled high blood pressure
- Congestive heart failure;
- Kidney disease ranging from mild to severe;
- SIADH (syndrome resulting from inappropriate antidiuretic hormonal secretion);
- Fever, infection, nausea, diarrhea, or any other condition that can cause excessive thirst, dehydration, or electrolyte imbalance
Desmopressin nasal can interact with some medicines that may cause harmful or unwanted effects. If you use the following medications, your doctor may have to alter your treatment plan:
- A "loop" (water pill) diuretic: bumetanide, ethacrynic acid, furosemide, and torsemide
- Purchase or use oral, inhaled or injectable steroid medications like Budesonide, Dexamethasone, Fluticasone, Mometasone or Prednisone; to treat depression.
If you have nasal or sinus issues (such as a deviated septum), desmopressin nasal may not be as effective.
Tell your doctor if:
- Nasal problems, such as a stuffy or runny nose
- A psychologic disorder that results in extreme or unusual thirst
- An infection or illness accompanied by fever, vomiting, or diarrhea
- Congestive heart disease.
- Kidney disease or inability to urinate
- A head injury or brain tumor;
- Cystic Fibrosis
It has not been shown to be harmful for unborn babies when taken during gestation. You should inform your physician if you're pregnant, planning to become pregnant, or using nasal desmopressin during this time to control excessive urination (common during gestation). Furthermore, desmopressin nasal spray should never be taken for excessive sweating that often accompanies gestation - please see here for further advice from experts regarding excessive perspiration (common during pregnancy). Your doctor can advise if this medication has any risks that prevent breastfeeding, such as birth control pills. Avoid giving this medication without first consulting with a pediatrician.
How to take Desmopressin nasal?
You may be asked to undergo a urine test by your doctor to ensure that desmopressin is the correct medicine for you. Read all the instructions or guides that come with your medication and follow the directions. Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed. Prime the nasal spray by spraying it four to five times into the air before your first use. Prime the nasal spray again if it hasn't been used for more than three days. If you experience diarrhea or vomiting that continues or are sweating excessively, call your doctor. This medicine can cause you to become dehydrated, leading to low pressure and a serious electrolyte imbalance. Your doctor may recommend frequent medical tests and adjust your dosage based on the results. You may need to undergo blood or urine testing before you can start taking desmopressin again if you have stopped using it. While using desmopressin, limit your water intake and other fluids. Too much water consumption could result in you shedding sodium from your system, which could ultimately result in its decline.This can lead to an electrolyte imbalance that is life-threatening.
Children and older adults who use desmopressin should limit their fluid intake. You should follow your doctor's advice about how much liquid you should consume. Store away from moisture or heat at room temperature.Keep the bottle upright when not being used. Noctiva that has not been opened should be stored in the fridge. Keep the medicine at room temperature after opening and use within 60 days. Keep the DDAVP nasal tube in your refrigerator. Don't freeze. You can store the bottles closed at room temperature for up to three weeks if refrigeration isn't available. Keep track of the number of sprays that you have used per bottle. Each bottle of desmopressin contains a certain number of sprays. Even if the medicine is still inside, throw away the spray after you have used the prescribed number of sprays. Pour it out into a fresh bottle. Use this medicine before the date of expiration printed on the label. If desmopressin is used to control bleeding, seek medical attention if it does not work.
What happens if I miss the dose?
If you are almost due for your next dose, skip the missed dose.Do not take two doses of any medicine at the same time. This could result in toxic overdosage.
What happens if I overdose?
Dial the Poison Control Hotline immediately on 1-800-222-1222 if a poisonous situation exists, or seek immediate medical care. Overdose symptoms include headaches, confusion, drowsiness, or rapid weight gain.
What should be avoided?
Avoid drinking large amounts of liquids before bedtime to help prevent nighttime urination.
Interaction with other drug
Tell your doctor if you are taking any other medications. Desmopressin may have interactions with other medicines, including:
- Any other nasal medication
- Antidepressants are a type of medication.
- Medications for bladder or urinary problems
- Cold or allergy medication;
- A diuretic, or "water pill".
- Heart or blood pressure medications;
- Medicine to treat mood disorders, bipolar disorder, or schizophrenia.
- A steroid medication;
- Seizure medicine: carbamazepine, lamotrigine;
- Nsaids are nonsteroidal anti-inflammatory medications (nonsteroidal anti-inflammatory drugs), such as aspirin (Advil), ibuprofen, naproxen, celecoxib (Aleve), diclofenac (indomethacin), meloxicam, and others.
This list is incomplete. Desmopressin can be affected by other drugs, such as prescription and non-prescription medicines, vitamins, and herbal products. This list does not include all drug interactions.
