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Palynziq

Name of the Generic: Pegvaliase peg-VAL-i-ase peg-VAL-i-ase peg-VAL-i-ase peg-VAL-i-ase
Drug Class: Miscellaneous metabolic agents

What is Palynziq?

Palynziq can be used to reduce the blood levels of phenylalanine in adult patients with phenylketonuria (PKU) not managed with other treatments.

Palynziq is only available from an approved pharmacy as part of its program.Palynziq is also employed for other purposes that are not covered in this medication guide.

Side effects of Palynziq

Stop taking the Palynziq injection immediately and seek urgent medical attention if you show symptoms that indicate an allergy.

  • Hives, rash, itching;
  • Confusion, dizziness, feeling like you might pass out;
  • Nausea, vomiting, diarrhea;
  • The loss of bladder control;
  • Fast heartbeats;
  • Wheezing and chest tightness; difficulty breathing;
  • Flushing (warmth, redness, warmth, or tingly sensation)
  • Swelling of your lips, face, and tongue.

Common adverse effects of Palynziq could include:

  • Cough and stuffy nose;
  • Pain in the throat and mouth;
  • Dizziness;
  • Anxiety;
  • Low levels of phenylalanine in the blood;
  • A skin reaction that spreads (itching and redness) and can last at least 14 days;
  • Pain, joint pain;
  • Nausea, vomiting, stomach pain, diarrhea;
  • Tiredness;
  • Bruises, tenderness, the area of redness, itching, or swelling in the area where the injection was administered.

This isn't an exhaustive list of possible side effects, and other effects may also be present. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Warnings

Palynziq may cause an allergic reaction. The first dose is administered in a medical setting.

See a doctor immediately in the event that you exhibit symptoms that indicate an allergy, like hives, wheezing, itching, dizziness, breathing difficulties, or swelling on your throat or face. Your doctor might recommend carrying an epinephrine injection kit with you at all times.

Before you take this drug

Palynziq could trigger a severe allergic reaction. Your physician may recommend an epinephrine injection kit in case of an extreme allergic reaction. Keep this kit of injections in your bag at all times.

Consult your physician if you suspect that you are unable to administer an injection of epinephrine in the event of an emergency.

Follow the instructions of your doctor regarding the use of Palynziq if you are pregnant. Controlling your phenylalanine levels is vital during pregnancy. Your name could be included in a pregnancy registry to monitor the effect of the drug on your baby.

Consult your doctor for advice on whether it is safe to breastfeed while taking this medication.Not recommended for use by anyone less than 18 years of age.

How to take Palynziq?

Follow the directions on the prescription label and review all medication guides and instruction sheets. Your doctor may alter the dosage. Make sure you take the medication precisely as directed.

Palynziq is injected beneath the skin. It is possible to receive other medications to help you avoid adverse side effects or even the possibility of an allergic reaction.The first dose in a medical setting is to ensure you don't have any allergic reactions.Take note of all the instructions for use. Speak to your pharmacist, or physician for assistance.

Make an injection just when you are able to give it. Contact your pharmacist if the medicine is cloudy, has changed color, or has particles.Don't shake the prefilled syringe, as you could destroy the medication.Your doctor will tell you the best place to inject Palynziq. Do not inject the same spot twice in the same row.

You might need someone around for at least one hour after injecting the medicine at home to look out for any signs of an allergic reaction. They will administer the injection of epinephrine as you require.

Check out the warning card about reactions to allergens and find out what signs to look out for. Make sure to keep the card in your wallet always.You'll need to take regular medical examinations.You'll need to adhere to an individualized diet. Follow the advice of your physician or dietitian. Know about the food items you should avoid eating.Place your medicine in the fridge. Do not freeze.

It is possible to store the medicine for up to 30 days at room temperature inside its original container, which is protected from sunlight. Do not store the medicine in the fridge. Get rid of any medicine you haven't used within 30 days or when it has expired. The deadline for expiration on the prescription label has been reached.Toss out a prefilled syringe after one use, even if there's still medicine inside.

Don't reuse needles or syringes. Put them in an impervious to puncture "sharps" container and dispose of it according to the laws of your state or municipality. Keep them out of the reach of pets and children.

What happens if I miss a dose?

Do not miss the missed dose, and take the next dose at the normal time. Don't take two doses at once.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Do not inject into the skin areas that are damaged, red, or tender. Avoid injecting into skin that is red, bruised, damaged, or irritated. Avoid injecting Palynziq into areas of the skin with birthmarks, moles, scars, or tattoos.

Interaction with other drugs

Other medications can affect Palynziq. Other medications can affect Palynziq, including medications that are prescribed and available over the counter, vitamins, and herbal products. Tell your physician about the other medications you use.